Product image of Ibuprofeno Stadapharm (Ibuprofen) supplied by GNH India

Ibuprofeno Stadapharm

Active Ingredient:
Ibuprofen
Origin:
EU

Ibuprofeno Stadapharm (Ibuprofen)

Ibuprofen, the active ingredient in Ibuprofeno Stadapharm, is a Nonsteroidal anti-inflammatory drug (NSAID) presented as a tablet for oral use. It treats mild to moderate pain, fever, and inflammatory conditions in adults and children.

GNH India supplies Ibuprofeno Stadapharm as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Laboratorio Stada, S.L.

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Indications & Clinical Uses

Ibuprofen is a non‑selective NSAID that reduces inflammation and pain by inhibiting prostaglandin synthesis.

  • Mild to moderate pain: provides analgesic relief for headaches, dental pain, musculoskeletal aches, and postoperative discomfort.
  • Fever: lowers elevated body temperature in febrile states.
  • Inflammatory arthritis: eases joint pain and swelling in osteoarthritis and rheumatoid arthritis.

How It Works

  • Ibuprofen exerts its effect by non‑selectively inhibiting cyclooxygenase‑1 (COX‑1) and cyclooxygenase‑2 (COX‑2) enzymes, which blocks the conversion of arachidonic acid to prostaglandins. The reduction in prostaglandin synthesis diminishes inflammation, lowers fever, and alleviates pain signals at peripheral nerve endings.

Side Effects

Common Side Effects

  • Gastrointestinal upset: nausea, dyspepsia, or abdominal discomfort.
  • Headache: mild to moderate intensity.
  • Dizziness or vertigo.
  • Mild skin rash or itching.
  • Elevated liver enzymes (asymptomatic).

Serious or Rare Side Effects

  • Gastrointestinal bleeding or ulcer perforation.
  • Severe allergic reactions such as anaphylaxis.
  • Renal impairment or acute kidney injury.
  • Hepatotoxicity with jaundice.
  • Cardiovascular events including myocardial infarction or stroke.
  • Blood dyscrasias such as thrombocytopenia.

Precautions & Warnings

Before initiating therapy, consider the following precautions:

  • Assess gastrointestinal risk: evaluate history of ulcers or bleeding.
  • Monitor renal function: avoid use in severe kidney disease without supervision.
  • Avoid in known hypersensitivity to ibuprofen or other NSAIDs.
  • Use the lowest effective dose: limit duration of therapy to the shortest necessary period.
  • Consider cardiovascular risk: exercise caution in patients with established heart disease.
  • Store at room temperature: keep in the original container, protect from moisture and heat.

Avoid Interactions

Ibuprofen may interact with several medicines; review the following categories:

Major Interactions (Avoid)

  • Anticoagulants (e.g., warfarin): increased risk of serious bleeding.
  • Other NSAIDs or COX‑2 inhibitors: additive gastrointestinal toxicity.
  • Selective serotonin reuptake inhibitors (SSRIs): heightened bleeding tendency.
  • Lithium: ibuprofen can raise serum lithium concentrations.
  • Methotrexate: reduced clearance leading to toxicity.

Moderate Interactions (Monitor Closely)

  • ACE inhibitors or ARBs: possible decline in renal function.
  • Diuretics: risk of renal impairment when combined.
  • Corticosteroids: increased ulcer risk.
  • Cyclosporine: enhanced nephrotoxicity.
  • Bismuth subsalicylate: additive antiplatelet effect.

Frequently Asked Questions

Ibuprofeno Stadapharm is a formulation of ibuprofen, an NSAID indicated for the relief of mild to moderate pain, reduction of fever, and mitigation of inflammation associated with conditions such as arthritis, musculoskeletal injuries, and postoperative discomfort.

Ibuprofen works by non‑selectively inhibiting the cyclooxygenase enzymes COX‑1 and COX‑2, which blocks the synthesis of prostaglandins. Lower prostaglandin levels reduce inflammation, lower body temperature, and diminish the perception of pain at peripheral nerve endings.

The appropriate dose of Ibuprofeno Stadapharm is determined by a qualified prescriber based on the patient’s age, weight, clinical condition, and response to therapy. Dosage instructions are provided on the prescription label and should be followed exactly.

Safety data for ibuprofen in pregnancy are limited; it is generally avoided in the third trimester due to potential fetal cardiovascular effects. Use during the first two trimesters should only occur if the benefit outweighs the risk and under medical supervision. Ibuprofen passes into breast milk in small amounts, so nursing mothers should consult a healthcare professional before use.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies, and procurement teams worldwide, confirming trade or institutional credentials before providing pricing, availability, shipping details (including any cold‑chain requirements if applicable), and necessary import documentation.

Ibuprofeno Stadapharm contains ibuprofen, which has a relatively rapid onset of analgesia and a moderate duration of action (4‑6 hours). Compared with naproxen, ibuprofen requires more frequent dosing but may have a slightly lower risk of gastrointestinal ulceration at equivalent analgesic doses. Unlike acetaminophen, ibuprofen also provides anti‑inflammatory effects.

Store Ibuprofeno Stadapharm at room temperature, ideally below 25 °C. Keep the tablets in the original packaging to protect them from moisture and direct sunlight. Do not refrigerate or freeze the product, and keep it out of reach of children.

Ibuprofeno Stadapharm is taken orally with a full glass of water. It may be taken with food or milk to lessen gastrointestinal irritation, although it can also be taken on an empty stomach if rapid onset is desired. Swallow tablets whole; do not crush or chew unless instructed by a healthcare professional.

The most serious risks include gastrointestinal bleeding or ulcer perforation, severe allergic reactions such as anaphylaxis, renal impairment especially in patients with pre‑existing kidney disease, and increased risk of cardiovascular events like myocardial infarction or stroke, particularly with high‑dose or prolonged use.

Ibuprofeno Stadapharm should be avoided in individuals with a known hypersensitivity to ibuprofen or other NSAIDs, those with active gastrointestinal bleeding or ulcer disease, patients with severe renal or hepatic impairment, and in the third trimester of pregnancy. It is also contraindicated in patients with established coronary artery disease who are at high cardiovascular risk.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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