Product image of Ibuprofeno Tolife (Ibuprofen) supplied by GNH India

Ibuprofeno Tolife

Active Ingredient:
Ibuprofen
Origin:
EU

Ibuprofeno Tolife (Ibuprofen)

Ibuprofen, the active ingredient in Ibuprofeno Tolife, is a nonsteroidal anti-inflammatory drug (NSAID) presented as an oral tablet for oral use. It relieves pain, reduces fever, and decreases inflammation in adults and children when appropriate.

GNH India supplies Ibuprofeno Tolife as a licensed, GDP-compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Towa Pharmaceutical S.A.

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Indications & Clinical Uses

Ibuprofen is an NSAID that reduces pain, fever, and inflammation by inhibiting prostaglandin synthesis.

  • Pain: provides analgesia for mild to moderate acute or chronic pain.
  • Fever: lowers elevated body temperature in febrile conditions.
  • Inflammation: diminishes swelling and discomfort associated with musculoskeletal inflammation.

How It Works

  • Ibuprofen exerts its effect by non‑selectively inhibiting cyclooxygenase‑1 (COX‑1) and cyclooxygenase‑2 (COX‑2) enzymes, which catalyze the conversion of arachidonic acid to prostaglandins. The reduction in prostaglandin production lessens peripheral nociceptor sensitisation, lowers the hypothalamic set‑point for temperature, and curtails the inflammatory cascade in affected tissues.

Side Effects

Common Side Effects

  • Gastrointestinal upset: nausea, dyspepsia, or abdominal discomfort.
  • Headache: mild to moderate intensity.
  • Dizziness: transient sensation of light‑headedness.
  • Rash: mild skin irritation or erythema.
  • Elevated liver enzymes: occasional asymptomatic increase.

Serious or Rare Side Effects

  • Gastrointestinal bleeding or ulcer perforation.
  • Acute renal impairment or failure.
  • Severe allergic reactions such as anaphylaxis.
  • Hepatotoxicity with marked liver enzyme elevation.
  • Stevens‑Johnson syndrome or toxic epidermal necrolysis.
  • Cardiovascular events including myocardial infarction or stroke.

Precautions & Warnings

Before using Ibuprofeno Tolife, consider the following precautions:

  • Assess gastrointestinal risk: avoid in patients with active ulcers or a history of GI bleeding.
  • Monitor renal function: use caution in individuals with impaired kidney function.
  • Use the lowest effective dose for the shortest duration needed.
  • Avoid in patients with known hypersensitivity to ibuprofen or other NSAIDs.
  • Exercise caution in patients with cardiovascular disease or hypertension.
  • Store at ambient temperature: keep in the original container, protect from moisture and direct sunlight.

Avoid Interactions

Ibuprofeno Tolife may interact with several medicines. Review the following groups:

Major Interactions (Avoid)

  • Anticoagulants (e.g., warfarin): increased risk of bleeding.
  • Other NSAIDs or aspirin: additive gastrointestinal toxicity.
  • Corticosteroids: heightened risk of ulceration and bleeding.

Moderate Interactions (Monitor Closely)

  • Lithium: ibuprofen may raise lithium serum levels.
  • Methotrexate: reduced clearance leading to toxicity.
  • ACE inhibitors or ARBs: possible reduction in renal function.
  • Diuretics: may potentiate renal effects.
  • SSRIs: increased bleeding tendency.

Frequently Asked Questions

Ibuprofeno Tolife contains ibuprofen, an NSAID indicated for the relief of mild to moderate pain, reduction of fever, and mitigation of inflammation associated with conditions such as musculoskeletal disorders, dental pain, and postoperative discomfort.

Ibuprofen works by non‑selectively inhibiting the cyclooxygenase enzymes COX‑1 and COX‑2, which reduces the synthesis of prostaglandins. Lower prostaglandin levels decrease peripheral pain signalling, lower the hypothalamic temperature set‑point, and limit the inflammatory response.

The appropriate dose of Ibuprofeno Tolife is determined by the prescribing healthcare professional based on the patient’s age, weight, clinical condition, and response. Typical adult regimens range from 200 mg to 400 mg every 4‑6 hours, not exceeding the maximum daily limit, but exact dosing must follow the prescriber’s order.

Safety data for ibuprofen in pregnancy are limited. It is generally avoided, especially in the third trimester, due to potential fetal cardiovascular effects. During breastfeeding, small amounts may pass into milk; caution is advised. Patients should consult their obstetrician or pediatrician before use.

To order Ibuprofeno Tolife, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including any temperature requirements), and necessary import documentation.

Ibuprofeno Tolife offers a well‑established balance of analgesic, antipyretic, and anti‑inflammatory activity similar to other non‑selective NSAIDs such as naproxen or diclofenac. Its safety profile, particularly gastrointestinal and renal considerations, is comparable, while individual patient tolerance and specific drug‑interaction profiles may guide selection among agents.

Store Ibuprofeno Tolife at ambient temperature, preferably below 25 °C. Keep the tablets in the original packaging, protect them from moisture, excessive heat, and direct sunlight to maintain potency throughout the shelf life.

Ibuprofeno Tolife is taken orally. Swallow the tablet whole with a full glass of water. It may be taken with or without food; taking it with food can reduce gastrointestinal discomfort in some patients.

Serious risks include gastrointestinal bleeding or ulcer perforation, acute renal failure, cardiovascular events such as myocardial infarction or stroke, and severe hypersensitivity reactions like anaphylaxis or Stevens‑Johnson syndrome. Patients should be monitored for these events, especially when used at high doses or for prolonged periods.

Ibuprofeno Tolife should be avoided in individuals with known hypersensitivity to ibuprofen or other NSAIDs, active peptic ulcer disease, severe renal or hepatic impairment, uncontrolled heart failure, and in the third trimester of pregnancy. Pediatric use should follow age‑specific guidelines provided by a healthcare professional.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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