Product image of Ibuprofeno Tricalma Ef (Ibuprofen) supplied by GNH India

Ibuprofeno Tricalma Ef

Active Ingredient:
Ibuprofen
Origin:
EU

Ibuprofeno Tricalma Ef (Ibuprofen)

Ibuprofen, the active ingredient in Ibuprofeno Tricalma Ef, is a nonsteroidal anti-inflammatory drug (NSAID) presented as an oral tablet for oral use. It provides relief from mild to moderate pain, reduces fever, and diminishes inflammation associated with conditions such as arthritis, and is indicated for use in adults and, when appropriate, in pediatric patients under professional guidance.

GNH India supplies Ibuprofeno Tricalma Ef as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Generis Farmacêutica, S.A.

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Indications & Clinical Uses

  • Ibuprofeno Tricalma Ef, an NSAID, acts on prostaglandin pathways to alleviate several common conditions.
  • Pain: reduces mild to moderate pain such as headache, dental or musculoskeletal discomfort.
  • Fever: lowers elevated body temperature associated with infections or inflammatory states.
  • Inflammation: diminishes swelling and redness in acute injuries.
  • Arthritis: helps manage symptoms of osteoarthritis and rheumatoid arthritis.

How It Works

  • Ibuprofen reversibly inhibits cyclooxygenase‑1 (COX‑1) and cyclooxygenase‑2 (COX‑2) enzymes, decreasing the conversion of arachidonic acid to prostaglandins. This reduction in prostaglandin synthesis leads to diminished pain signaling, lowered fever, and attenuation of inflammatory responses in affected tissues.

Side Effects

Common Side Effects

  • Stomach upset or heartburn
  • Nausea or vomiting
  • Dizziness or light‑headedness
  • Headache
  • Mild rash or itching
  • Diarrhea

Serious or Rare Side Effects

  • Gastrointestinal bleeding or ulcer perforation
  • Severe allergic reaction (anaphylaxis)
  • Liver injury (hepatitis)
  • Kidney impairment or failure
  • Cardiovascular events such as heart attack or stroke
  • Blood disorders (e.g., thrombocytopenia)

Precautions & Warnings

Before using Ibuprofeno Tricalma Ef, consider the following precautions:

  • Assess gastrointestinal risk: avoid in patients with active ulcers or a history of GI bleeding.
  • Evaluate cardiovascular status: use the lowest effective dose in patients with heart disease.
  • Review renal function: monitor kidney parameters in those with renal impairment.
  • Consider pregnancy: category B, but avoid use in the third trimester.
  • Avoid concomitant use with other NSAIDs or anticoagulants unless directed.
  • Store at ambient temperature: keep in the original pack, protect from moisture.

Avoid Interactions

Ibuprofeno Tricalma Ef may interact with several medicines.

Major Interactions (Avoid)

  • Warfarin – increased risk of bleeding.
  • Selective serotonin reuptake inhibitors (SSRIs) – heightened gastrointestinal bleeding.
  • ACE inhibitors – possible decline in renal function.

Moderate Interactions (Monitor Closely)

  • Other NSAIDs – additive gastrointestinal toxicity.
  • Methotrexate – reduced clearance, risk of toxicity.
  • Lithium – increased serum lithium levels.

Frequently Asked Questions

Ibuprofeno Tricalma Ef is an oral ibuprofen product indicated for relief of mild to moderate pain, reduction of fever, and treatment of inflammatory conditions such as arthritis. It is used in adults and, when appropriate, in pediatric patients under medical guidance.

Ibuprofen exerts its effect by reversibly inhibiting cyclooxygenase enzymes COX‑1 and COX‑2, which reduces the synthesis of prostaglandins that mediate pain, fever and inflammation. This inhibition decreases the inflammatory response and lowers body temperature.

The dosage is individualized by the prescribing healthcare professional based on the patient’s age, weight, condition being treated and response. Typical adult dosing ranges from 200 mg to 400 mg every 4‑6 hours, not exceeding the maximum daily limit, but the exact regimen must be set by the prescriber.

Ibuprofen is classified as pregnancy category B, indicating no proven risk in the first two trimesters, but it is generally avoided in the third trimester due to potential fetal complications. It passes into breast milk in small amounts; nursing mothers should consult a healthcare provider before use.

To place an order, submit an enquiry on the product page at gnhindia.com specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Ibuprofen shares the same COX inhibition mechanism as other non‑steroidal anti‑inflammatory drugs such as naproxen or diclofenac, but it has a relatively short half‑life and is often preferred for short‑term pain and fever relief. Compared with aspirin, ibuprofen has a lower risk of gastrointestinal bleeding at standard doses, though all NSAIDs carry similar cautions.

The product should be stored at ambient temperature, below 25 °C, in its original packaging to protect it from moisture and light. Keep the container tightly closed and out of reach of children. Do not store in a refrigerator or freezer unless specifically instructed on the label.

Ibuprofeno Tricalma Ef is taken orally, usually with a full glass of water. It may be taken with food or milk to lessen stomach irritation. The tablets should be swallowed whole and not crushed or chewed unless the product formulation specifically permits it.

Serious adverse events include gastrointestinal bleeding or ulcer perforation, severe allergic reactions such as anaphylaxis, kidney injury, and increased risk of cardiovascular events like heart attack or stroke, especially with high doses or prolonged use. Patients should seek immediate medical attention if they experience signs of these conditions.

Individuals with a known hypersensitivity to ibuprofen or other NSAIDs, those with active peptic ulcer disease, severe heart failure, uncontrolled hypertension, significant renal or hepatic impairment, and pregnant women in the third trimester should not use this product. Consultation with a healthcare professional is essential before initiating therapy.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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