Product image of Ibuprom Zatoki Tabs (Phenylephrine Hydrochloride, Ibuprofen) supplied by GNH India

Ibuprom Zatoki Tabs

Active Ingredient:
Phenylephrine Hydrochloride, Ibuprofen
Origin:
EU

Ibuprom Zatoki Tabs (Phenylephrine Hydrochloride, Ibuprofen)

Ibuprofen and phenylephrine hydrochloride, the active ingredients in Ibuprom Zatoki Tabs, are an NSAID and a sympathomimetic decongestant presented as tablets for oral use. They provide analgesic, antipyretic, anti‑inflammatory relief and nasal decongestion for adults experiencing mild to moderate pain, fever or congestion.

GNH India supplies Ibuprom Zatoki Tabs as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Us Pharmacia Sp. Z O.O.

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Indications & Clinical Uses

Ibuprom Zatoki combines an NSAID and a nasal decongestant to address pain, fever, inflammation and congestion.

  • Pain relief: reduces mild to moderate headache, toothache, muscular or joint pain.
  • Fever reduction: lowers elevated body temperature associated with common infections.
  • Nasal congestion: relieves blocked nasal passages caused by colds, sinusitis or allergic rhinitis.

How It Works

  • Ibuprofen inhibits cyclo‑oxygenase (COX‑1 and COX‑2) enzymes, decreasing prostaglandin synthesis and producing analgesic, antipyretic and anti‑inflammatory effects. Phenylephrine hydrochloride acts as an alpha‑1 adrenergic receptor agonist, causing vasoconstriction of the nasal mucosa, which reduces swelling and eases nasal airflow.

Side Effects

Common Side Effects

  • Gastrointestinal discomfort: mild stomach pain or indigestion.
  • Nausea: feeling of queasiness after ingestion.
  • Dizziness: transient light‑headedness.
  • Headache: mild to moderate head pain.

Serious or Rare Side Effects

  • Gastrointestinal bleeding: visible blood in stool or vomiting blood.
  • Severe allergic reaction: rash, swelling, difficulty breathing (anaphylaxis).
  • Hypertensive crisis: sudden, severe increase in blood pressure.
  • Liver enzyme elevation: abnormal liver function tests.
  • Renal impairment: reduced kidney function, especially with prolonged use.

Precautions & Warnings

Before using Ibuprom Zatoki, consider the following precautions.

  • Assess renal function: avoid in severe renal impairment.
  • Check for hypersensitivity: do not use if allergic to ibuprofen or phenylephrine.
  • Monitor blood pressure: use caution in patients with hypertension.
  • Avoid concurrent NSAIDs: do not combine with other non‑steroidal anti‑inflammatory drugs.
  • Pregnancy and breastfeeding: consult a healthcare professional before use.
  • Store at ambient temperature below 25°C: keep in the original pack, protect from moisture.

Avoid Interactions

Ibuprom Zatoki may interact with several medicines.

Major Interactions (Avoid)

  • Anticoagulants (e.g., warfarin): increased risk of bleeding.
  • Selective serotonin reuptake inhibitors (SSRIs): heightened gastrointestinal bleeding risk.
  • Monoamine oxidase inhibitors (MAOIs): potential hypertensive crisis with phenylephrine.

Moderate Interactions (Monitor Closely)

  • ACE inhibitors or diuretics: may blunt antihypertensive effect.
  • Lithium: phenylephrine can raise lithium serum concentrations.

Frequently Asked Questions

Ibuprom Zatoki is an over‑the‑counter tablet that combines ibuprofen and phenylephrine hydrochloride to provide relief from mild to moderate pain, reduce fever, lessen inflammation, and alleviate nasal congestion associated with colds or sinusitis.

Ibuprofen blocks cyclo‑oxygenase enzymes (COX‑1 and COX‑2), which reduces the production of prostaglandins—chemicals that cause pain, fever, and inflammation—thereby delivering analgesic, antipyretic, and anti‑inflammatory effects.

The appropriate dose of Ibuprom Zatoki is determined by a prescriber based on the individual’s age, weight, medical condition, and response to therapy. Patients should follow the healthcare professional’s instructions and the product label.

Safety in pregnancy and lactation has not been fully established for this combination. Women who are pregnant, planning pregnancy, or breastfeeding should discuss potential risks and benefits with their healthcare provider before using the product.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Compared with single‑ingredient ibuprofen tablets, Ibuprom Zatoki adds phenylephrine, offering simultaneous nasal decongestion. Unlike pure decongestant sprays, it also provides systemic analgesic and anti‑inflammatory benefits, making it useful when pain, fever and congestion coexist.

Store the tablets at ambient temperature below 25 °C, in their original packaging, and protect them from moisture and direct sunlight. Do not store in a refrigerator or freezer.

Ibuprom Zatoki is taken orally with a full glass of water. It can be taken with or without food, but taking it with food may reduce stomach irritation. Swallow the tablet whole; do not crush or chew.

Serious risks include gastrointestinal bleeding, severe allergic reactions (anaphylaxis), hypertensive crisis, liver enzyme elevation, and renal impairment, especially with prolonged use or in patients with pre‑existing conditions.

Individuals with known hypersensitivity to ibuprofen, phenylephrine, or any component of the tablet should avoid it. It is also contraindicated in patients with severe renal or hepatic impairment, uncontrolled hypertension, or those taking certain interacting medications such as anticoagulants, SSRIs, or MAO inhibitors.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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