Product image of Ibusal (Ibuprofen) supplied by GNH India

Ibusal

Active Ingredient:
Ibuprofen
Origin:
EU

Ibusal (Ibuprofen)

Ibuprofen, the active ingredient in Ibusal, is a non‑steroidal anti‑inflammatory drug (NSAID) presented as an oral dosage form for oral use. It is used to relieve mild to moderate pain, reduce fever, and diminish inflammation in adults, children and adolescents.

GNH India supplies Ibusal as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide. The company adheres to stringent quality standards and provides reliable logistics for global distribution. Our network ensures timely delivery and regulatory compliance across diverse markets.

Manufacturer / TM Owner

Orion Corporation

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Indications & Clinical Uses

Ibuprofen acts systemically to reduce inflammation and pain by inhibiting cyclo‑oxygenase enzymes, making it useful for several common conditions.

  • Headache: relief of mild to moderate tension‑type or migraine‑associated pain.
  • Dental pain: reduction of postoperative or acute dental discomfort.
  • Musculoskeletal pain: alleviation of strains, sprains and low‑back aches.
  • Fever: lowering of elevated body temperature in infections or inflammatory states.
  • Arthritis: mitigation of joint inflammation and stiffness in osteoarthritis and rheumatoid arthritis.

How It Works

  • Ibuprofen non‑selectively inhibits the cyclo‑oxygenase enzymes COX‑1 and COX‑2, blocking the conversion of arachidonic acid to prostaglandins. This reduction in prostaglandin synthesis decreases peripheral sensitisation of nociceptors, lowers the hypothalamic set‑point for temperature, and limits inflammatory cell recruitment at sites of tissue injury.

Side Effects

Like all NSAIDs, ibuprofen may cause unwanted reactions ranging from mild to severe.

Common Side Effects

  • Stomach upset: dyspepsia or mild abdominal discomfort.
  • Nausea: feeling of queasiness, sometimes with vomiting.
  • Dizziness: transient light‑headedness or vertigo.

Serious or Rare Side Effects

  • Gastrointestinal bleeding: occult or overt bleeding, potentially leading to anemia.
  • Kidney injury: acute renal impairment, especially in dehydrated patients.
  • Severe allergic reaction: anaphylaxis or angioedema requiring immediate medical attention.

Precautions & Warnings

Before using Ibusal, consider the following safety measures.

  • Assess gastrointestinal risk: evaluate history of ulcers or bleeding before initiating therapy.
  • Use lowest effective dose: limit duration and dose to the minimum needed for symptom control.
  • Avoid in known hypersensitivity: discontinue if rash, wheeze or swelling occurs.
  • Monitor renal function: check kidney parameters in patients with pre‑existing renal disease or dehydration.
  • Store at ambient temperature: keep below 25 °C in the original container, protect from moisture and light.

Avoid Interactions

Ibuprofen can interact with several medicines; some require avoidance while others need close monitoring.

Major Interactions (Avoid)

  • Anticoagulants (e.g., warfarin): increased risk of serious bleeding.
  • ACE inhibitors (e.g., enalapril): potential reduction of antihypertensive effect and renal impairment.

Moderate Interactions (Monitor Closely)

  • Diuretics (e.g., furosemide): possible decrease in diuretic efficacy.
  • Lithium: ibuprofen may raise lithium serum concentrations.
  • Methotrexate: increased risk of methotrexate toxicity, especially at high doses.

Frequently Asked Questions

Ibusal contains ibuprofen, an over‑the‑counter NSAID used to relieve mild‑to‑moderate pain such as headache, dental pain and musculoskeletal aches, to lower fever, and to reduce inflammation in conditions like arthritis. It is intended for short‑term use in adults and children as directed by a healthcare professional.

Ibuprofen non‑selectively inhibits the cyclo‑oxygenase enzymes COX‑1 and COX‑2, which are required for the conversion of arachidonic acid to prostaglandins. By lowering prostaglandin production, it reduces the sensitisation of nerve endings to pain, diminishes fever‑inducing signals in the hypothalamus, and limits inflammation in affected tissues.

The appropriate dose of Ibusal is determined by the prescribing clinician based on the patient’s age, weight, the severity of symptoms, and any relevant medical conditions. Dosage recommendations follow national guidelines for ibuprofen, and patients should follow the prescriber’s instructions and the product label.

Safety of ibuprofen in pregnancy and lactation depends on the trimester and individual risk factors. Generally, ibuprofen is avoided in the third trimester because of possible fetal complications, and caution is advised during the first two trimesters. Breastfeeding mothers should consult a healthcare professional before use.

To request Ibusal, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Ibusal (ibuprofen) shares the core anti‑inflammatory and analgesic mechanisms of other non‑steroidal anti‑inflammatory drugs such as naproxen or diclofenac, but it has a relatively short half‑life and a well‑established safety profile at recommended doses. Choice of NSAID often depends on individual tolerability, dosing frequency and specific clinical considerations.

Ibusal should be stored at ambient temperature, preferably below 25 °C, in its original packaging to protect it from moisture and light. Keep the product out of reach of children and do not use it after the expiry date printed on the label.

Ibusal is taken orally, usually with a full glass of water. It may be taken with or without food; however, taking it with food or milk can help minimise gastrointestinal discomfort. The tablet should be swallowed whole and not chewed or crushed unless directed by a healthcare professional.

The most serious adverse events linked to ibuprofen include gastrointestinal bleeding or ulceration, acute kidney injury, and severe hypersensitivity reactions such as anaphylaxis. Patients with a history of ulcer disease, renal impairment, or known NSAID allergy should be monitored closely or avoid use.

Ibusal should be avoided by individuals with a documented hypersensitivity to ibuprofen or other NSAIDs, those with active gastrointestinal bleeding or ulcer disease, patients with severe renal or hepatic impairment, and anyone who has experienced a serious cardiovascular event while using NSAIDs. Consultation with a healthcare provider is essential before starting therapy.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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