Product image of Ibustar (Ibuprofen) supplied by GNH India

Ibustar

Active Ingredient:
Ibuprofen
Origin:
EU

Ibustar (Ibuprofen)

Ibuprofen, the active ingredient in Ibustar, is a nonsteroidal anti-inflammatory drug presented as an oral tablet for oral use. It treats pain, fever and inflammation in adults and children when appropriate.

GNH India supplies Ibustar as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Berlin-Chemie Ag

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Indications & Clinical Uses

Ibustar (ibuprofen) works by reducing inflammation and pain through cyclooxygenase inhibition, making it useful for several common conditions.

  • Pain: Provides relief from mild to moderate nociceptive pain such as headaches, dental pain, or musculoskeletal aches.
  • Fever: Lowers elevated body temperature associated with infections or inflammatory states.
  • Inflammation: Decreases swelling and discomfort in conditions like arthritis or soft‑tissue injuries.

How It Works

  • Ibuprofen exerts its therapeutic effect by non‑selectively inhibiting the cyclooxygenase enzymes COX‑1 and COX‑2. This inhibition blocks the conversion of arachidonic acid to prostaglandins, thereby reducing the mediators responsible for pain sensation, fever generation, and inflammatory swelling.

Side Effects

Ibustar may cause a range of adverse reactions, from mild to serious.

Common Side Effects

  • Stomach upset: nausea, dyspepsia or abdominal discomfort.
  • Headache: mild to moderate headache.
  • Dizziness: transient feeling of light‑headedness.
  • Rash: mild skin erythema or itching.

Serious or Rare Side Effects

  • Gastrointestinal bleeding: ulceration or bleeding in the stomach or intestines.
  • Renal impairment: reduced kidney function or acute kidney injury.
  • Severe allergic reaction: anaphylaxis, angioedema or bronchospasm.

Precautions & Warnings

Before using Ibustar, consider the following precautions to minimize risks.

  • Assess medical history: review any history of gastrointestinal ulcers, bleeding disorders, or cardiovascular disease.
  • Use lowest effective dose: employ the smallest dose needed for symptom control and limit duration.
  • Avoid concurrent NSAIDs: do not combine with other nonsteroidal anti‑inflammatory drugs or aspirin unless directed.
  • Monitor renal function: patients with kidney disease should have renal function checked regularly.
  • Pregnancy and lactation: discuss with a healthcare professional before use during pregnancy or breastfeeding.
  • Store at ambient temperature: keep below 25 °C in the original container, protected from moisture and direct sunlight.

Avoid Interactions

Ibustar can interact with several medicines; awareness of these interactions helps ensure safe therapy.

Major Interactions (Avoid)

  • Anticoagulants (e.g., warfarin): increased risk of serious bleeding.
  • High‑dose corticosteroids: heightened gastrointestinal ulcer risk.
  • Selective serotonin reuptake inhibitors (SSRIs): additive bleeding tendency.

Moderate Interactions (Monitor Closely)

  • ACE inhibitors or ARBs: may reduce renal function, especially in dehydrated patients.
  • Diuretics: potential for reduced kidney perfusion and electrolyte imbalance.
  • Lithium: ibuprofen can raise lithium serum levels, requiring monitoring.

Frequently Asked Questions

Ibustar contains ibuprofen, an NSAID indicated for relief of mild to moderate pain, reduction of fever, and mitigation of inflammation associated with conditions such as headache, dental pain, musculoskeletal aches, arthritis, and postoperative discomfort. It is prescribed for adults and, when appropriate, for children under medical supervision.

Ibuprofen exerts its effect by non‑selectively inhibiting the cyclooxygenase enzymes COX‑1 and COX‑2, which are required for the conversion of arachidonic acid to prostaglandins. By decreasing prostaglandin synthesis, it reduces the sensitisation of nerve endings to pain, lowers the hypothalamic set‑point for temperature, and diminishes inflammatory swelling.

The specific dose of Ibustar is determined by the prescribing healthcare professional based on the patient’s age, weight, clinical condition, and response to therapy. The prescriber will select the appropriate strength, frequency, and duration in accordance with approved labeling and individual therapeutic needs.

The safety of ibuprofen during pregnancy and lactation depends on the trimester and clinical circumstances. Generally, ibuprofen is avoided in the third trimester because of potential fetal cardiovascular effects, and caution is advised during the first two trimesters. Breastfeeding mothers should consult a healthcare provider, as ibuprofen does pass into milk in small amounts.

To place an order, visit the product page on gnhindia.com, submit an enquiry with the required quantity, and provide institutional or trade credentials. GNH India’s commercial team will verify the information, then respond with pricing, availability, shipping terms (including any cold‑chain requirements if applicable), and necessary import documentation.

Ibustar’s active ingredient, ibuprofen, shares the same class mechanism as other non‑selective NSAIDs such as naproxen or diclofenac. Compared with some alternatives, ibuprofen has a relatively short half‑life, which may allow flexible dosing but may also require more frequent administration for sustained effect. Its safety profile is well‑characterised, though individual tolerability varies.

Ibustar tablets should be stored at ambient temperature, preferably below 25 °C, in the original blister or bottle to protect from moisture and light. Keep the product out of reach of children and do not use if the packaging is damaged or the tablets appear discoloured.

Ibustar is taken orally, with or without food, as directed by the prescriber. Swallow the tablet whole with a full glass of water; do not crush or chew unless the formulation specifically permits it. The dosing interval and total daily dose are individualized by the healthcare professional.

The most serious adverse events linked to ibuprofen include gastrointestinal bleeding or ulceration, severe renal impairment, and hypersensitivity reactions such as anaphylaxis. Patients with a history of ulcer disease, cardiovascular disorders, or kidney dysfunction should be monitored closely, and any signs of serious bleeding or allergic reaction require immediate medical attention.

Ibustar is contraindicated in individuals with known hypersensitivity to ibuprofen or other NSAIDs, those with active gastrointestinal ulceration or bleeding, and patients with severe heart failure or advanced renal disease. It should also be avoided in the third trimester of pregnancy and in patients receiving certain anticoagulants without careful risk assessment.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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