Product image of Ibutact (Ibuprofen) supplied by GNH India

Ibutact

Active Ingredient:
Ibuprofen
Origin:
EU

Ibutact (Ibuprofen)

Ibuprofen, the active ingredient in Ibutact, is a nonsteroidal anti-inflammatory drug presented as an oral dosage form for oral use. It provides analgesic, antipyretic, and anti‑inflammatory effects for mild to moderate pain, fever, and inflammatory conditions such as arthritis.

GNH India supplies Ibutact as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide. The company adheres to EU quality standards and ensures consistent product availability across global markets.

Manufacturer / TM Owner

Tactica Pharmaceuticals Sp. Z O.O.

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Indications & Clinical Uses

Ibuprofen acts systemically to reduce pain, fever, and inflammation associated with various conditions.

  • Mild to moderate pain: provides analgesic relief for headaches, dental pain, musculoskeletal discomfort, and postoperative pain.
  • Fever: lowers elevated body temperature by acting on the hypothalamic heat‑regulating center.
  • Arthritis (inflammatory joint conditions): decreases joint inflammation and associated pain, improving mobility.

How It Works

  • Ibuprofen non‑selectively inhibits cyclooxygenase‑1 and cyclooxygenase‑2 enzymes, reducing the conversion of arachidonic acid to prostaglandins. Lower prostaglandin levels diminish peripheral sensitization of nociceptors, lower the hypothalamic set‑point for temperature, and decrease inflammatory exudate formation, resulting in analgesic, antipyretic, and anti‑inflammatory effects.

Side Effects

Ibuprofen may cause a range of adverse reactions, varying from common, mild events to rare, serious conditions.

Common Side Effects

  • Gastrointestinal upset: nausea, dyspepsia, or abdominal discomfort.
  • Headache: mild to moderate intensity.
  • Dizziness or vertigo.
  • Rash or mild skin irritation.

Serious or Rare Side Effects

  • Gastrointestinal bleeding or ulceration: potentially life‑threatening.
  • Renal impairment: reduced kidney function, especially with prolonged use.
  • Severe allergic reactions: anaphylaxis, angioedema, or Stevens‑Johnson syndrome.
  • Hepatic injury: elevated liver enzymes or hepatitis.

Precautions & Warnings

When using ibuprofen, consider the following precautions to minimize risk and ensure safe therapy.

  • Assess renal function: avoid or adjust dose in patients with existing kidney disease.
  • Monitor gastrointestinal health: contraindicated in active peptic ulcer disease.
  • Avoid concurrent anticoagulants: increased risk of bleeding.
  • Use cautiously in asthma: may precipitate bronchospasm.
  • Pregnancy and lactation: consult a healthcare professional before use.
  • Store at ambient temperature: keep in the original container, protect from moisture and heat.

Avoid Interactions

Ibuprofen can interact with several medicines, altering efficacy or safety.

Major Interactions (Avoid)

  • Anticoagulants (e.g., warfarin): heightened bleeding risk.
  • Selective COX‑2 inhibitors (e.g., celecoxib): additive renal toxicity.
  • High‑dose aspirin: increased gastrointestinal ulcer risk.

Moderate Interactions (Monitor Closely)

  • ACE inhibitors (e.g., enalapril): may reduce renal function, especially in dehydrated patients.
  • Diuretics (e.g., furosemide): risk of reduced kidney perfusion.
  • Lithium: ibuprofen can raise serum lithium levels, requiring monitoring.

Frequently Asked Questions

Ibutact contains ibuprofen, which is indicated for the relief of mild to moderate pain such as headaches, dental or musculoskeletal pain, for the reduction of fever, and for the management of inflammatory disorders like osteoarthritis and rheumatoid arthritis.

Ibuprofen blocks the activity of cyclooxygenase‑1 and cyclooxygenase‑2 enzymes, decreasing the synthesis of prostaglandins that mediate pain, fever, and inflammation. Lower prostaglandin levels reduce peripheral nerve sensitisation, lower the hypothalamic temperature set‑point, and limit inflammatory swelling.

The appropriate dose of ibuprofen is determined by a prescriber based on the patient’s age, weight, clinical condition, and treatment duration. Healthcare professionals select the strength, frequency, and length of therapy that best matches the individual’s therapeutic needs.

Safety of ibuprofen during pregnancy and lactation depends on the trimester and individual risk factors. Women who are pregnant, planning pregnancy, or breastfeeding should discuss use with their healthcare provider, who can weigh potential benefits against possible risks to the fetus or infant.

To request Ibutact, submit an enquiry on the product page at gnhindia.com indicating the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Ibuprofen and naproxen belong to the same NSAID class and share similar mechanisms, but ibuprofen generally has a shorter half‑life, leading to more frequent dosing, whereas naproxen provides longer‑lasting pain control with once‑ or twice‑daily dosing. Individual response, safety profile and drug‑interaction potential guide the choice between them.

Ibutact should be stored at ambient temperature, below 25 °C, in its original packaging. Keep the product away from moisture, direct sunlight and excessive heat to maintain stability and potency throughout its shelf life.

Ibutact is taken orally, with or without food, as directed by a healthcare professional. Swallow tablets or capsules whole with a full glass of water. If an oral liquid form is supplied, use a calibrated measuring device to ensure accurate dosing.

Serious risks include gastrointestinal bleeding or ulceration, severe allergic reactions such as anaphylaxis or Stevens‑Johnson syndrome, renal impairment especially with prolonged use, and cardiovascular events in susceptible individuals. Prompt medical attention is required if any of these events are suspected.

Individuals with a known hypersensitivity to ibuprofen or other NSAIDs, active peptic ulcer disease, severe heart failure, uncontrolled hypertension, significant renal or hepatic impairment, and those in the third trimester of pregnancy should avoid ibuprofen unless specifically advised by a physician.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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