Product image of Ibuvit D3 (Colecalciferol) supplied by GNH India

Ibuvit D3

Active Ingredient:
Colecalciferol
Origin:
EU

Ibuvit D3 (Colecalciferol)

Colecalciferol, the active ingredient in Ibuvit D3, is a vitamin D presented as an oral supplement for oral use. It is used to address vitamin D deficiency and support bone health in individuals with insufficient dietary intake or limited sun exposure.

GNH India supplies Ibuvit D3 as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Zaklady Farmaceutyczne Polpharma S.A.

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Indications & Clinical Uses

Ibuvit D3 (colecalciferol) is used to correct deficiencies in the vitamin D pathway and support calcium metabolism.

  • Vitamin D deficiency: restores adequate serum 25‑hydroxyvitamin D levels.
  • Osteoporosis or low bone mass: supports bone mineralization and reduces fracture risk.
  • Hypocalcemia: helps maintain normal calcium and phosphate concentrations in the blood.

How It Works

  • Colecalciferol is absorbed in the intestine and converted in the liver to 25‑hydroxyvitamin D, then in the kidney to the active hormone calcitriol. Calcitriol binds the nuclear vitamin D receptor, enhancing transcription of proteins that increase intestinal absorption of calcium and phosphate, thereby promoting bone mineralization and maintaining mineral homeostasis.

Side Effects

Common Side Effects

  • Nausea: mild stomach upset may occur.
  • Constipation: occasional difficulty passing stool.
  • Dry mouth: reduced salivation reported.
  • Headache: transient mild headache.

Serious or Rare Side Effects

  • Hypercalcemia: elevated blood calcium with symptoms such as weakness or arrhythmia.
  • Kidney stones: calcium deposition in the urinary tract.
  • Severe allergic reaction: rash, swelling, or anaphylaxis.
  • Cardiac arrhythmia: irregular heartbeat in cases of extreme toxicity.

Precautions & Warnings

Before initiating therapy, consider the following precautions:

  • Baseline assessment: evaluate serum calcium and 25‑hydroxyvitamin D levels.
  • Monitoring: watch for signs of hypercalcemia during treatment.
  • Renal impairment: adjust dose or frequency in patients with reduced kidney function.
  • Concomitant calcium: avoid high‑dose calcium supplements unless medically indicated.
  • Store at ambient temperature: keep in the original container, protect from moisture and light.

Avoid Interactions

Colecalciferol may interact with several medicines. Review the following:

Major Interactions (Avoid)

  • Thiazide diuretics: increase risk of hypercalcemia.
  • Excess vitamin A: synergistic hypercalcemia potential.
  • Aluminum‑containing antacids: reduce vitamin D absorption.
  • High‑dose calcium supplements: may precipitate hypercalcemia.

Moderate Interactions (Monitor Closely)

  • Corticosteroids: may diminish vitamin D effectiveness.
  • Orlistat: can decrease absorption of fat‑soluble vitamins.
  • Phenobarbital and phenytoin: accelerate vitamin D metabolism, possibly lowering efficacy.

Frequently Asked Questions

Ibuvit D3 contains colecalciferol, a form of vitamin D, and is used to correct vitamin D deficiency, support normal bone mineralization, and maintain appropriate calcium and phosphate levels in the blood.

After oral absorption, colecalciferol is converted in the liver to 25‑hydroxyvitamin D and then in the kidney to the active hormone calcitriol. Calcitriol binds the vitamin D receptor, stimulating intestinal absorption of calcium and phosphate and promoting bone health.

The appropriate dose of Ibuvit D3 is determined by a qualified healthcare professional based on the patient’s serum vitamin D level, age, weight, and clinical condition. Prescribers set the regimen to achieve target serum concentrations safely.

Safety data for colecalciferol in pregnancy and lactation are limited. Healthcare providers should evaluate the risk‑benefit ratio for each individual, considering that vitamin D is essential for fetal bone development but excessive doses may pose risks.

To place an order, submit an enquiry on the Ibuvit D3 product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and import documentation.

Ibuvit D3 provides colecalciferol, the natural dietary form of vitamin D, which is widely used and well‑studied. Compared with synthetic analogues, colecalciferol relies on the body’s own conversion steps, offering flexibility in dosing and a familiar safety profile.

Store Ibuvit D3 at ambient temperature, preferably below 25 °C. Keep the product in its original packaging, protect it from moisture, heat and direct sunlight, and ensure the container is tightly closed to maintain stability.

Ibuvit D3 is taken orally, usually with or without food, as directed by a healthcare professional. The tablet or capsule is swallowed whole with a glass of water; it should not be crushed or chewed unless specifically advised.

The most serious risks involve excessive vitamin D intake leading to hypercalcemia, which can cause kidney stones, cardiac arrhythmias, and severe neurological symptoms. Prompt medical attention is required if signs of high calcium levels appear.

Individuals with known hypersensitivity to colecalciferol or any excipients, patients with hypercalcemia, severe renal impairment, or those taking medications that markedly increase calcium levels should avoid using Ibuvit D3 unless supervised by a physician.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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