Product image of Icalziss (Calcium Chloride Dihydrate) supplied by GNH India

Icalziss

Active Ingredient:
Calcium Chloride Dihydrate
Origin:
EU

Icalziss (Calcium Chloride Dihydrate)

Calcium chloride dihydrate, the active ingredient in Icalziss, is an electrolyte solution presented as a sterile solution for extracorporeal use. It provides calcium ions to correct calcium deficiency and support electrolyte balance in patients requiring intravenous supplementation. It is commonly employed in critical care settings, such as surgery and intensive care units, where rapid calcium repletion is essential.

GNH India supplies Icalziss as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, transplant centres, oncology centres and pharmacies worldwide. The company adheres to stringent quality standards and provides regulatory documentation to facilitate import and distribution across multiple regions.

Manufacturer / TM Owner

Vantive Belgium

1
Pack/s
This product is added to your enquiry list

Request a Quote

Please fill out the form below and our team will get back to you shortly with pricing and further information.

A minimum order value applies. Our team will confirm the exact amount or quantity after reviewing your requirements.

Indications & Clinical Uses

Icalziss is used to manage conditions associated with calcium deficiency and electrolyte imbalance.

  • Calcium deficiency: restores serum calcium levels to support neuromuscular function and bone metabolism.
  • Hypocalcemia: provides rapid intravenous calcium to raise low blood calcium concentrations in acute settings.
  • Electrolyte replacement: supplies calcium ions as part of comprehensive electrolyte therapy during surgery or critical care.

How It Works

  • After intravenous administration, calcium chloride dihydrate dissociates into calcium (Ca²⁺) and chloride ions. The free calcium ions increase extracellular calcium concentration, contributing to normal cardiac contractility, muscle contraction, neurotransmission, and blood coagulation. By augmenting serum calcium, the solution helps re‑establish electrolyte homeostasis and supports physiological processes that depend on calcium as a second messenger. Additionally, the chloride component contributes to overall ionic balance without significant metabolic effect.

Side Effects

Calcium chloride dihydrate may be associated with several adverse reactions following intravenous administration.

Common Side Effects

  • Injection site pain: mild discomfort or burning sensation at the infusion site, usually transient.
  • Phlebitis: inflammation of the vein used for administration, presenting as redness, swelling, and tenderness.
  • Hypercalcemia (mild): transient elevation of serum calcium that typically does not produce symptoms.
  • Nausea: occasional feeling of queasiness or upset stomach during or shortly after infusion.

Serious or Rare Side Effects

  • Severe hypercalcemia: marked increase in calcium levels that can cause muscle weakness, confusion, and cardiac arrhythmias.
  • Cardiac arrhythmias: abnormal heart rhythms, including ventricular tachycardia, that may be life‑threatening.
  • Tissue necrosis: damage to surrounding tissue if the solution leaks out of the vein (extravasation), leading to ulceration.
  • Anaphylactic reaction: rare severe allergic response with hives, airway swelling, and hypotension requiring emergency care.

Precautions & Warnings

When using Icalziss, clinicians should observe specific precautions to minimize risks and ensure safe administration.

  • Renal impairment: monitor serum calcium and renal function closely during therapy.
  • Cardiac disease: avoid rapid infusion in patients with known arrhythmias or heart failure.
  • Hyperparathyroidism: use with caution as calcium load may exacerbate the condition.
  • Concurrent calcium products: assess total calcium intake to prevent excess.
  • Store at ambient temperature: keep in original container, protect from moisture and light.

Avoid Interactions

Calcium chloride dihydrate can interact with certain medications, affecting calcium balance or drug efficacy.

Major Interactions (Avoid)

  • Vitamin D analogues: increase risk of severe hypercalcemia when combined.
  • Loop diuretics: may cause rapid shifts in calcium levels, requiring careful monitoring.
  • Bisphosphonates: calcium supplementation can reduce the drug’s effectiveness on bone resorption.

Moderate Interactions (Monitor Closely)

  • Magnesium supplements: may interfere with calcium homeostasis and require dose adjustment.
  • Aluminum‑containing antacids: can bind calcium and reduce its absorption.
  • ACE inhibitors: monitor blood pressure as calcium infusion may influence vascular tone.

Frequently Asked Questions

Icalziss is an intravenous electrolyte solution containing calcium chloride dihydrate. It is employed to correct calcium deficiency, treat hypocalcemia, and provide calcium as part of electrolyte replacement therapy in surgical, intensive‑care and other clinical settings where rapid calcium repletion is required.

When administered intravenously, calcium chloride dihydrate dissociates into calcium and chloride ions. The free calcium ions raise extracellular calcium concentration, supporting cardiac contractility, muscle contraction, nerve transmission, and blood clotting, thereby helping to restore normal electrolyte balance.

The dose of Icalziss is individualized by the prescribing clinician based on the patient’s serum calcium level, clinical condition, weight, renal function and the intended rate of correction. No fixed regimen is provided; the prescriber sets the appropriate infusion rate and total amount.

Safety data for calcium chloride dihydrate in pregnancy and lactation are limited. Because calcium plays a critical role in fetal development, the product should only be used if the potential benefit justifies any potential risk. Consultation with a maternal‑fetal specialist is recommended.

To order Icalziss, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including any cold‑chain requirements) and the necessary import documentation.

Icalziss delivers calcium as calcium chloride, which provides a rapid increase in serum calcium and a higher elemental calcium content per millilitre compared with calcium gluconate or calcium acetate. It is therefore preferred in acute settings where swift correction is needed, whereas other calcium salts are often used for slower, oral supplementation.

Icalziss should be stored at ambient temperature, below 25 °C, in its original sealed container. Protect the product from moisture, direct sunlight and extreme temperature fluctuations. Before use, inspect the solution for particulate matter or discoloration and follow aseptic techniques for intravenous preparation.

Icalziss is administered intravenously by a qualified healthcare professional. The solution is typically diluted in an appropriate carrier fluid and infused through a peripheral or central vein at a rate determined by the prescriber, taking care to monitor the patient’s vital signs and serum calcium levels throughout the infusion.

The most serious risks include severe hypercalcemia, which can lead to cardiac arrhythmias, muscle weakness, and neurological disturbances, as well as tissue necrosis if the solution extravasates. Rarely, anaphylactic reactions may occur, requiring immediate emergency treatment.

Icalziss should be avoided in patients with known hypersensitivity to calcium chloride, uncontrolled hypercalcemia, severe renal failure where calcium clearance is impaired, and in those with conditions such as hyperparathyroidism unless closely monitored. Clinicians should assess each patient’s medical history before initiating therapy.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

Disclaimer

At GNH India, we aim to provide information that is expert-reviewed, accurate, and reliable. However, all content on this platform is intended for general informational purposes only and does not constitute professional medical advice, diagnosis, or treatment. While efforts are made to maintain accuracy and currency, the information may contain errors, omissions, or may not reflect the latest developments. Always consult a qualified healthcare professional regarding any medical concerns.

All product names, brand names, trademarks and registered trademarks displayed on this website are the property of their respective owners. This website and its operator are not affiliated with, endorsed by, or authorized by any such trade mark owners unless expressly stated. Any reference to product names or trademarks is made solely for descriptive and informational purposes. No commercial relationship, sponsorship, approval, or association with any trademark owner should be inferred. Information provided herein does not constitute promotion, advertising, or an offer for sale of any medicinal product and is intended solely for general informational purposes.

All trademarks and brand names displayed on this website are used strictly in accordance with the provisions of the Trade Marks Act, 1999, specifically Sections 30 and 30(1) governing fair use. Trademark ownership has been accurately attributed under the "Manufacturer/ TM Owner" section in compliance with statutory requirements.

Related Products

Other formulations containing Calcium Chloride Dihydrate

A

A
A

A
A

A
A

A

Browse all products →

Ordering Process

Simple, Secure, and Seamless

Learn how our streamlined ordering process guarantees fast, compliant, and reliable access to essential medicines worldwide.

Quote request form

01

Submit Quote Request Form

Tell us what medications you need by filling out our simple form and uploading a valid document.

Price estimate review

02

We Review & Send Estimate

Our licensed pharmacists will verify your details and provide you with a detailed cost estimate.

Secure payment

03

Confirm & Make Payment

Discuss any queries, approve the estimate, and complete your payment.

Worldwide delivery

04

Get Delivered

Your medicines, safely packed and delivered to your door or nearest airport — hassle-free.

Regulatory recognitions

Quality You Can Trust

Our internationally recognized certifications underscore our commitment to safety, quality, and excellence.

SGS GSDP Certification

GSDP Compliant from SGS

URS ISO 9001

URS ISO 9001 Certification

FDA Maharashtra

Licensed by FDA Maharashtra

IEC License DGFT

IEC License issued by DGFT