Product image of Icatibant Universal Farma (Icatibant) supplied by GNH India

Icatibant Universal Farma

Active Ingredient:
Icatibant
Origin:
EU

Icatibant Universal Farma (Icatibant)

Icatibant, the active ingredient in Icatibant Universal Farma, is a bradykinin B2 receptor antagonist presented as a solution for subcutaneous injection use. It treats acute attacks of hereditary angioedema in patients with C1‑inhibitor deficiency.

GNH India supplies Icatibant Universal Farma as a licensed, GDP-compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Universal Farma, S.L.

1
Pack/s
This product is added to your enquiry list

Request a Quote

Please fill out the form below and our team will get back to you shortly with pricing and further information.

A minimum order value applies. Our team will confirm the exact amount or quantity after reviewing your requirements.

Indications & Clinical Uses

  • Icatibant acts on the bradykinin pathway to relieve swelling in hereditary angioedema.
  • Hereditary angioedema type I: rapid relief of swelling during acute attacks.
  • Hereditary angioedema type II: rapid relief of swelling during acute attacks.
  • Hereditary angioedema with normal C1‑inhibitor (HAE‑nC1-INH): symptomatic control of acute episodes.

How It Works

  • Icatibant selectively blocks the bradykinin B2 receptor, preventing bradykinin from binding and triggering the cascade that leads to increased vascular permeability and edema. By antagonizing this receptor, the drug halts the development of swelling associated with hereditary angioedema attacks, providing rapid symptom relief.

Side Effects

Common Side Effects

  • Injection site pain: mild to moderate discomfort at the injection site.
  • Redness or erythema: localized skin redness.
  • Swelling at injection site: transient increase in local tissue volume.
  • Nausea: occasional upset stomach.
  • Headache: mild to moderate.
  • Dizziness: transient light‑headedness.

Serious or Rare Side Effects

  • Anaphylactic reaction: severe allergic response requiring immediate medical attention.
  • Airway angioedema: swelling that may compromise breathing.
  • Severe hypotension: marked drop in blood pressure.
  • Thrombocytopenia: low platelet count.
  • Stevens‑Johnson syndrome: rare severe skin reaction.
  • Serum sickness–like reaction: systemic immune response.

Precautions & Warnings

Icatibant should be used under medical supervision with attention to patient history and comorbidities.

  • Pregnancy: consult prescriber; limited safety data available.
  • Breastfeeding: weigh potential risks and benefits before use.
  • Renal impairment: monitor renal function; dose adjustment not routinely required.
  • Concomitant ACE inhibitors: may reduce therapeutic effect; monitor closely.
  • Known hypersensitivity: avoid in patients with documented allergy to icatibant or its excipients.
  • Store at 2-8°C: keep refrigerated, protect from light, do not freeze or shake.

Avoid Interactions

Icatibant may interact with several drug classes; monitoring is advised.

Major Interactions (Avoid)

  • ACE inhibitors: may diminish icatibant efficacy.
  • Angiotensin receptor blockers (ARBs): potential reduction in therapeutic effect.
  • Other bradykinin B2 receptor antagonists: additive antagonism not recommended.

Moderate Interactions (Monitor Closely)

  • Warfarin: monitor INR as icatibant may affect anticoagulation.
  • NSAIDs: increased risk of local injection‑site reactions.
  • Diuretics: observe blood pressure for possible fluctuations.

Frequently Asked Questions

Icatibant Universal Farma is used to treat acute attacks of hereditary angioedema (HAE) in patients with C1‑inhibitor deficiency. By blocking the bradykinin B2 receptor, it rapidly reduces swelling and associated symptoms during an HAE episode.

Icatibant works by selectively antagonizing the bradykinin B2 receptor. This prevents bradykinin from increasing vascular permeability, thereby stopping the cascade that leads to the swelling characteristic of hereditary angioedema attacks.

The dose of icatibant is determined by the prescribing clinician based on the patient’s condition, severity of the attack, and regulatory guidelines. Healthcare professionals set the exact amount and frequency for each individual case.

Safety data for icatibant in pregnancy and lactation are limited. It should only be used if the potential benefit justifies the potential risk to the fetus or infant, and the decision must be made by a qualified healthcare provider.

To order, submit an enquiry on the product page at gnhindia.com with the required quantity. GNH India supplies hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including cold‑chain if needed) and import documentation.

Icatibant is a bradykinin B2 receptor antagonist, whereas other approved HAE therapies include C1‑inhibitor concentrates and kallikrein inhibitors. Icatibant provides rapid subcutaneous relief without requiring intravenous administration, making it convenient for emergency self‑treatment.

Icatibant should be stored refrigerated at 2‑8 °C, protected from light, and must not be frozen or shaken. Keep the product in its original packaging to maintain stability until use.

Icatibant is given as a subcutaneous injection, typically into the abdomen or thigh. The injection is performed by a trained healthcare professional or, for self‑administration, after proper instruction on technique and safety.

Serious risks include anaphylaxis, airway angioedema that can compromise breathing, severe hypotension, thrombocytopenia, and rare severe skin reactions such as Stevens‑Johnson syndrome. Immediate medical attention is required if any of these occur.

Icatibant should not be used by individuals with known hypersensitivity to the drug or any of its excipients. Caution is also advised for patients with uncontrolled cardiovascular disease or those receiving concurrent ACE inhibitors without medical supervision.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

Disclaimer

At GNH India, we aim to provide information that is expert-reviewed, accurate, and reliable. However, all content on this platform is intended for general informational purposes only and does not constitute professional medical advice, diagnosis, or treatment. While efforts are made to maintain accuracy and currency, the information may contain errors, omissions, or may not reflect the latest developments. Always consult a qualified healthcare professional regarding any medical concerns.

All product names, brand names, trademarks and registered trademarks displayed on this website are the property of their respective owners. This website and its operator are not affiliated with, endorsed by, or authorized by any such trade mark owners unless expressly stated. Any reference to product names or trademarks is made solely for descriptive and informational purposes. No commercial relationship, sponsorship, approval, or association with any trademark owner should be inferred. Information provided herein does not constitute promotion, advertising, or an offer for sale of any medicinal product and is intended solely for general informational purposes.

All trademarks and brand names displayed on this website are used strictly in accordance with the provisions of the Trade Marks Act, 1999, specifically Sections 30 and 30(1) governing fair use. Trademark ownership has been accurately attributed under the "Manufacturer/ TM Owner" section in compliance with statutory requirements.

Related Products

Other formulations containing Icatibant

A

A
A

A
A

A
A

A

Browse all products →

Ordering Process

Simple, Secure, and Seamless

Learn how our streamlined ordering process guarantees fast, compliant, and reliable access to essential medicines worldwide.

Quote request form

01

Submit Quote Request Form

Tell us what medications you need by filling out our simple form and uploading a valid document.

Price estimate review

02

We Review & Send Estimate

Our licensed pharmacists will verify your details and provide you with a detailed cost estimate.

Secure payment

03

Confirm & Make Payment

Discuss any queries, approve the estimate, and complete your payment.

Worldwide delivery

04

Get Delivered

Your medicines, safely packed and delivered to your door or nearest airport — hassle-free.

Regulatory recognitions

Quality You Can Trust

Our internationally recognized certifications underscore our commitment to safety, quality, and excellence.

SGS GSDP Certification

GSDP Compliant from SGS

URS ISO 9001

URS ISO 9001 Certification

FDA Maharashtra

Licensed by FDA Maharashtra

IEC License DGFT

IEC License issued by DGFT