Iclusig15 (Ponatinib Tablet) 15mg

Iclusig 15mg tablets contain ponatinib, a kinase inhibitor prescribed for certain blood cancers. This oral treatment supports disease management when other options are unsuitable. Ideal for patients seeking targeted therapy under medical supervision. Suitable for ambient storage.

Strength

15mg

Pack Size

30s

Storage

Ambient

Manufacturer / TM Owner

Incyte Switzerland

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Pack/s

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Indications & Clinical Uses

Ponatinib is primarily used to treat chronic myeloid leukemia (CML) and Philadelphia chromosome-positive acute lymphoblastic leukemia (Ph+ ALL). It targets specific genetic mutations to help control cancer progression. Patients with resistance or intolerance to other therapies may benefit from this medication. Always prescribed after careful evaluation by a healthcare provider.

Side Effects

Common effects of ponatinib include fatigue, skin rash, and gastrointestinal discomfort like nausea or diarrhea. Some users report headaches or joint pain during treatment. These effects vary by individual and often lessen over time. Regular monitoring helps manage any persistent symptoms.

Precautions & Warnings

Store Iclusig 15mg tablets at room temperature away from moisture and heat. Keep out of reach of children and pets. Avoid crushing or splitting tablets unless advised by a pharmacist. Inform your doctor about any pre-existing conditions or allergies before starting treatment.

Avoid Interactions

Ponatinib may interact with strong CYP3A inhibitors or inducers, altering its effectiveness. Grapefruit products can increase ponatinib levels, while St. John’s wort may reduce them. Discuss all medications, including over-the-counter and supplements, with your healthcare provider. Alcohol use should be limited during treatment.

Frequently Asked Questions

Ponatinib 15mg is used to treat certain types of leukemia, including CML and Ph+ ALL, particularly when other therapies are not suitable.

Store Iclusig 15mg tablets at room temperature in a dry place, away from direct sunlight and out of reach of children.

Avoid grapefruit or grapefruit juice while taking ponatinib, as it may increase the risk of side effects.

Common side effects include fatigue, skin rash, nausea, diarrhea, headaches, and joint pain.

Ponatinib is a targeted therapy, not a traditional chemotherapy, as it blocks specific proteins involved in cancer growth.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated: 29 Jul 2026

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