Product image of Idoka (Sildenafil Citrate) supplied by GNH India

Idoka

Active Ingredient:
Sildenafil Citrate
Origin:
EU

Idoka (Sildenafil Citrate)

Sildenafil citrate, the active ingredient in Idoka, is a Phosphodiesterase type 5 inhibitor presented as a tablet for oral use. It is prescribed for the treatment of erectile dysfunction and pulmonary arterial hypertension in adult patients.
GNH India supplies Idoka as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Stada Genéricos, S.L.

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Indications & Clinical Uses

  • Idoka belongs to the phosphodiesterase type 5 inhibitor class and is used in conditions where vasodilation improves clinical outcomes.
  • Erectile dysfunction: enhances erectile response by increasing blood flow to the corpus cavernosum.
  • Pulmonary arterial hypertension: improves exercise capacity and delays disease progression by relaxing pulmonary vascular smooth muscle.

How It Works

  • Sildenafil citrate selectively inhibits the enzyme phosphodiesterase type 5 (PDE5), preventing the breakdown of cyclic guanosine monophosphate (cGMP). Elevated cGMP levels lead to smooth‑muscle relaxation in the corpus cavernosum and pulmonary vasculature, facilitating increased blood flow and improved erectile function or reduced pulmonary arterial pressure.

Side Effects

Adverse reactions may vary in frequency and severity.

Common Side Effects

  • Headache: mild to moderate pain often transient.
  • Flushing: warmth and redness of the face or upper body.
  • Dyspepsia: indigestion or upset stomach.
  • Nasal congestion: blocked or runny nose.
  • Visual disturbance: blurred vision or color tinge.
  • Back pain: muscular discomfort, usually self‑limiting.

Serious or Rare Side Effects

  • Priapism: prolonged erection lasting more than four hours, requiring emergency care.
  • Sudden hearing loss: abrupt decrease or loss of hearing.
  • Severe hypotension: marked drop in blood pressure, especially with nitrates.
  • Non‑arteritic anterior ischemic optic neuropathy (NAION): sudden vision loss.
  • Myocardial infarction: heart attack in susceptible individuals.

Precautions & Warnings

Before prescribing Idoka, clinicians should evaluate specific risk factors and comorbidities.

  • Cardiovascular assessment: ensure patient can tolerate sexual activity.
  • Nitrate use: avoid concurrent use due to risk of severe hypotension.
  • Severe hepatic impairment: dose adjustment may be required.
  • Ocular conditions: caution in patients with retinal disorders.
  • Concomitant alpha‑blockers: monitor for additive blood‑pressure effects.
  • Store at ambient temperature: keep below 25 °C in the original container, protect from moisture and direct sunlight.

Avoid Interactions

Idoka can interact with several medication classes; awareness helps prevent adverse events.

Major Interactions (Avoid)

  • Nitrates (e.g., nitroglycerin): may cause life‑threatening hypotension.
  • Guanylate cyclase stimulators (e.g., riociguat): additive vasodilatory effect.
  • Potent CYP3A4 inhibitors (e.g., ketoconazole, itraconazole): increase sildenafil exposure.
  • Certain protease inhibitors (e.g., ritonavir): elevate plasma levels.
  • Alpha‑blockers (high dose): risk of marked blood‑pressure drop.

Moderate Interactions (Monitor Closely)

  • CYP3A4 inducers (e.g., rifampin, carbamazepine): may reduce efficacy.
  • Antihypertensive agents: possible additive blood‑pressure lowering.
  • Other PDE5 inhibitors: avoid concurrent use.
  • Alcohol: may enhance hypotensive effect.
  • Diuretics: monitor electrolytes and blood pressure.

Frequently Asked Questions

Idoka contains sildenafil citrate and is indicated for adult patients with erectile dysfunction and for those diagnosed with pulmonary arterial hypertension. In both conditions the drug works by promoting vasodilation, which improves blood flow to the penis or reduces pressure in the pulmonary arteries.

Sildenafil citrate selectively blocks the phosphodiesterase type 5 enzyme, which normally degrades cyclic guanosine monophosphate (cGMP). By preserving cGMP, the drug relaxes smooth muscle in the corpus cavernosum and pulmonary vasculature, allowing increased blood flow that supports erection or lowers pulmonary arterial pressure.

The appropriate dose of Idoka is determined by a qualified prescriber based on the individual’s medical condition, response to therapy, and any concomitant medications. Patients should follow the dosing instructions provided by their healthcare professional and not adjust the dose on their own.

Sildenafil citrate is classified as pregnancy category unknown, and its safety has not been established for pregnant or nursing women. It should only be used during pregnancy or lactation if clearly needed and prescribed by a physician after weighing potential risks and benefits.

To request Idoka, submit an enquiry on the product page at gnhindia.com specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including any cold‑chain requirements) and necessary import documentation.

Idoka (sildenafil citrate) shares the same mechanism as other PDE5 inhibitors such as tadalafil and vardenafil. While all promote erection by increasing cGMP, they differ in onset, duration of action, and dosing frequency. Sildenafil typically has a rapid onset (30–60 minutes) with a shorter half‑life, making it suitable for on‑demand use.

Idoka should be stored at ambient temperature, preferably below 25 °C. Keep the tablets in the original blister pack or container, protect them from moisture, heat and direct sunlight, and keep them out of reach of children.

Idoka is taken orally, usually with water, about 30 to 60 minutes before sexual activity or as directed for pulmonary arterial hypertension. The tablet should be swallowed whole and not crushed, chewed, or broken. Food may delay absorption but does not affect overall efficacy.

The most serious risks include priapism (a prolonged erection lasting more than four hours), sudden hearing loss, severe hypotension especially when combined with nitrates, and rare vision loss due to non‑arteritic anterior ischemic optic neuropathy. Any of these events require immediate medical attention.

Idoka is contraindicated in patients who are taking nitrates or nitric‑oxide donors, have a known hypersensitivity to sildenafil or any tablet excipients, or have had a recent stroke or myocardial infarction without medical clearance. Caution is also advised for individuals with severe cardiovascular disease, uncontrolled hypertension, or significant liver impairment.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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