Idroclorotiazide Aurobindo (Hydrochlorothiazide)

Hydrochlorothiazide inhibits the Na⁺/Cl⁻ symporter in the distal convoluted tubule of the kidney, decreasing reabsorption of sodium and chloride. This promotes increased urinary excretion of these ions together with water, lowering plasma volume and peripheral vascular resistance, which helps control blood pressure and fluid accumulation.

The appropriate dose is determined by the prescribing healthcare professional based on the individual’s medical condition, response to therapy, and renal function. Dosage adjustments are made according to clinical judgment and patient monitoring.

Safety data for hydrochlorothiazide in pregnancy and lactation are limited. It should only be used when the potential benefit justifies any possible risk to the fetus or infant, and the decision should be made by the treating physician.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any required import documentation.

Hydrochlorothiazide is a thiazide‑type diuretic, primarily acting on the distal convoluted tubule, whereas loop diuretics such as furosemide act on the ascending limb of the loop of Henle and are generally more potent. Thiazides are often preferred for long‑term hypertension management due to their favorable duration of action and lower risk of ototoxicity.

Store the product at ambient temperature, preferably below 25 °C, in the original packaging to protect it from moisture and light. Keep the container tightly closed and out of reach of children.

The medication is taken orally, usually with a full glass of water. It can be taken with or without food, but patients should follow the specific instructions provided by their prescriber.

Serious adverse effects include severe electrolyte disturbances (especially low potassium), acute gout attacks, hypersensitivity reactions such as anaphylaxis, significant hypotension, and rare blood disorders like agranulocytosis. Prompt medical attention is required if any of these occur.

Hydrochlorothiazide is contraindicated in patients with known hypersensitivity to the drug, anuria, or severe renal impairment. Caution is also advised for individuals with uncontrolled diabetes, gout, or those taking medications that may interact significantly, such as lithium or certain NSAIDs.