Product image of Ifenec (Econazole Nitrate) supplied by GNH India

Ifenec

Active Ingredient:
Econazole Nitrate
Origin:
EU

Ifenec (Econazole Nitrate)

Econazole nitrate, the active ingredient in Ifenec, is an imidazole antifungal presented as a topical formulation for skin use. It treats fungal infections such as athlete's foot, ringworm and candidiasis in adult and pediatric patients.
GNH India supplies Ifenec as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Italfarmaco S.P.A

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Indications & Clinical Uses

Ifenec is an imidazole antifungal used to manage superficial fungal infections of the skin and mucous membranes.

  • Tinea corporis: reduces erythema, scaling and itching caused by ringworm of the body.
  • Tinea cruris: alleviates inflammation and lesions in the groin area caused by fungal infection.
  • Tinea pedis: clears foot skin infection, decreasing scaling, redness and discomfort.
  • Candidiasis: treats cutaneous candidal infections, relieving erythema and maceration.

How It Works

  • Econazole nitrate inhibits ergosterol synthesis by blocking the fungal cytochrome P450 enzyme lanosterol 14α‑demethylase. This disruption of the cell membrane sterol composition compromises fungal cell integrity, leading to inhibition of growth and eventual cell death of susceptible dermatophytes and yeasts.

Side Effects

Topical application of Ifenec may be associated with local skin reactions.

Common Side Effects

  • Burning sensation: transient warmth at the application site.
  • Itching: mild pruritus following use.
  • Redness: localized erythema.
  • Dryness: skin may feel less moist.
  • Peeling: mild desquamation of treated skin.

Serious or Rare Side Effects

  • Severe allergic reaction: swelling, hives or difficulty breathing.
  • Contact dermatitis: intense rash or blistering.
  • Skin ulceration: breakdown of epidermis.
  • Secondary bacterial infection: pus or increased pain at the site.

Precautions & Warnings

Before using Ifenec, consider the following safety measures.

  • Allergic history: avoid if known hypersensitivity to econazole or other imidazoles.
  • Open wounds: do not apply on extensive broken skin or severe abrasions.
  • Pediatric use: consult a healthcare professional before treating children.
  • Concomitant skin products: avoid using other topical agents on the same area unless directed.
  • Store at ambient temperature: keep below 25 °C, in the original container, protected from moisture and direct sunlight.

Avoid Interactions

Econazole nitrate may interact with other topical agents or systemic drugs that affect skin integrity.

Major Interactions (Avoid)

  • Corticosteroid creams: may reduce antifungal efficacy.
  • Occlusive dressings: increase systemic absorption, raising risk of toxicity.
  • Systemic azole antifungals: potential additive inhibition of cytochrome P450 enzymes.

Moderate Interactions (Monitor Closely)

  • Antiseptic solutions: may cause irritation when combined.
  • Herbal skin preparations: monitor for unexpected skin reactions.

Frequently Asked Questions

Ifenec is a topical antifungal medication indicated for the treatment of superficial fungal infections such as tinea corporis (ringworm of the body), tinea cruris (jock itch), tinea pedis (athlete’s foot) and cutaneous candidiasis. It helps relieve symptoms like redness, scaling, itching and discomfort associated with these infections.

Econazole nitrate, the active ingredient in Ifenec, blocks the fungal enzyme lanosterol 14α‑demethylase, which is essential for ergosterol synthesis. By disrupting ergosterol production, the drug compromises the integrity of the fungal cell membrane, inhibiting growth and leading to the death of susceptible dermatophytes and yeasts.

The dosage of Ifenec is determined by the prescribing healthcare professional based on the type and severity of the infection, the patient’s age, and the area of skin involved. Patients should follow the specific instructions provided by their prescriber and the product label.

Safety data for econazole nitrate in pregnancy and lactation are limited. The product should only be used if the potential benefit justifies any potential risk to the fetus or infant. Pregnant or nursing individuals should discuss use with their healthcare provider before starting treatment.

To order Ifenec, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India supplies hospitals, pharmacies and procurement teams worldwide. After submission, the sales team will verify trade or institutional credentials and respond with pricing, availability, shipping details (including any cold‑chain requirements) and necessary import documentation.

Ifenec (econazole nitrate) belongs to the imidazole class, offering broad‑spectrum activity against dermatophytes and yeasts. Compared with allylamine agents such as terbinafine, econazole may have a slightly slower onset but is effective for a wide range of superficial infections. Choice of therapy depends on infection type, patient tolerance and local resistance patterns.

Ifenec should be stored at ambient temperature, preferably below 25 °C. Keep the product in its original packaging, protect it from moisture, direct sunlight and extreme heat. Do not freeze the preparation, and ensure the container is tightly closed when not in use.

Ifenec is applied topically to the affected skin area. The prescribed amount is spread thinly over the lesion and a small margin of surrounding healthy skin, usually twice daily or as directed by a healthcare professional. Hands should be washed before and after application, and the treated area should be allowed to dry.

Serious adverse reactions are rare but may include severe allergic responses such as swelling, hives, difficulty breathing, or contact dermatitis with intense rash or blistering. If any of these symptoms occur, discontinue use immediately and seek medical attention.

Individuals with a known hypersensitivity to econazole nitrate, other imidazole antifungals, or any component of the formulation should avoid using Ifenec. It should also be avoided on extensive broken skin, deep wounds, or in patients where a systemic antifungal is required without medical supervision.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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