Product image of Igamad (Human Anti-D Immunoglobulin) supplied by GNH India

Igamad

Active Ingredient:
Human Anti-D Immunoglobulin
Origin:
EU

Igamad (Human Anti-D Immunoglobulin)

Human Anti-D Immunoglobulin, the active ingredient in Igamad, is an immunoglobulin presented as a solution for injection for intramuscular use. It prevents Rh alloimmunization in Rh‑negative pregnant women and reduces the risk of hemolytic disease of the newborn.

GNH India supplies Igamad as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals worldwide.

Manufacturer / TM Owner

Instituto Grifols, S.A.

1
Pack/s
This product is added to your enquiry list

Request a Quote

Please fill out the form below and our team will get back to you shortly with pricing and further information.

A minimum order value applies. Our team will confirm the exact amount or quantity after reviewing your requirements.

Indications & Clinical Uses

  • Igamad, an anti‑D immunoglobulin, is used in the Rh‑D antigen pathway to prevent maternal sensitization.
  • Rh‑negative pregnancy: prevents maternal immune sensitization to the D antigen, reducing risk of hemolytic disease of the newborn.
  • Fetal‑maternal hemorrhage: provides passive immunity to avoid alloimmunization after bleeding events.
  • Newborn care: lowers incidence of hemolytic disease in Rh‑positive infants born to Rh‑negative mothers.

How It Works

  • Human Anti-D Immunoglobulin binds specifically to RhD‑positive erythrocytes circulating in the maternal bloodstream. By coating these cells, the immunoglobulin masks the D antigen, preventing the maternal immune system from recognizing and producing anti‑D antibodies. This passive immunization blocks the sensitization process, thereby averting subsequent hemolytic disease in future pregnancies.

Side Effects

Common Side Effects

  • Injection site pain or tenderness.
  • Mild fever or chills.
  • Headache.
  • Nausea or mild gastrointestinal upset.

Serious or Rare Side Effects

  • Anaphylactic or severe allergic reaction.
  • Acute hemolysis.
  • Renal impairment or failure.
  • Thromboembolic events such as deep vein thrombosis.

Precautions & Warnings

  • Igamad should be administered only after confirming Rh‑negative status and assessing patient history.
  • Screening: verify Rh‑negative blood type before use.
  • Allergy assessment: check for IgA deficiency or prior reactions to immunoglobulins.
  • Pregnancy risk: use only when clinical benefit outweighs potential risk.
  • Concurrent blood products: avoid mixing with RhD‑positive blood components without compatibility testing.
  • Store at 2-8°C: keep refrigerated, protect from light, do not freeze or shake.

Avoid Interactions

Igamad may interact with other therapies that affect immune function or blood viscosity.

Major Interactions (Avoid)

  • Concurrent IVIG therapy: increased risk of hyperviscosity.
  • Live vaccines: possible interference with vaccine efficacy.
  • RhD‑positive blood products: may trigger hemolysis.

Moderate Interactions (Monitor Closely)

  • Corticosteroids: may mask early signs of allergic reaction.
  • Anticoagulants: monitor for bleeding if hemolysis occurs.

Frequently Asked Questions

Igamad is used to prevent Rh alloimmunization in Rh‑negative pregnant women and to reduce the risk of hemolytic disease of the newborn. It provides passive immunity by targeting the D antigen on fetal red blood cells that may enter the maternal circulation.

Human Anti-D Immunoglobulin binds to RhD‑positive red blood cells, masking the D antigen. This prevents the maternal immune system from recognizing the antigen and forming anti‑D antibodies, thereby averting sensitization and subsequent hemolytic disease in future pregnancies.

The dosage of Igamad is determined by the prescribing clinician based on the patient’s Rh status, gestational age, and clinical scenario. Healthcare providers calculate the appropriate volume to achieve effective prophylaxis.

Igamad is specifically indicated for use in pregnant women who are Rh‑negative. It is considered safe when administered according to clinical guidelines. Limited data are available for breastfeeding, and the decision should be made by the prescriber after evaluating the benefit‑risk profile.

To order Igamad, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including cold‑chain where needed), and import documentation.

Igamad is a human anti‑D immunoglobulin similar in composition to other licensed anti‑D preparations. Differences may lie in manufacturing processes, concentration, and regulatory approvals. Clinical efficacy and safety are comparable when used according to guidelines.

Igamad should be stored at 2‑8 °C in a refrigerator. Keep the vial in its original packaging, protect it from light, and avoid freezing or shaking the solution to maintain product stability.

Igamad is supplied as a sterile solution for injection and is administered intramuscularly. The injection is typically given in the deltoid or gluteal muscle by a qualified healthcare professional following aseptic technique.

Serious risks include severe allergic reactions such as anaphylaxis, acute hemolysis, renal impairment, and rare thromboembolic events. Patients should be monitored closely during and after administration for any signs of these adverse reactions.

Igamad should not be given to individuals with known hypersensitivity to human immunoglobulin preparations, IgA deficiency with anti‑IgA antibodies, or those who have previously experienced severe reactions to anti‑D immunoglobulin. Clinical judgment is required for all contraindications.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

Disclaimer

At GNH India, we aim to provide information that is expert-reviewed, accurate, and reliable. However, all content on this platform is intended for general informational purposes only and does not constitute professional medical advice, diagnosis, or treatment. While efforts are made to maintain accuracy and currency, the information may contain errors, omissions, or may not reflect the latest developments. Always consult a qualified healthcare professional regarding any medical concerns.

All product names, brand names, trademarks and registered trademarks displayed on this website are the property of their respective owners. This website and its operator are not affiliated with, endorsed by, or authorized by any such trade mark owners unless expressly stated. Any reference to product names or trademarks is made solely for descriptive and informational purposes. No commercial relationship, sponsorship, approval, or association with any trademark owner should be inferred. Information provided herein does not constitute promotion, advertising, or an offer for sale of any medicinal product and is intended solely for general informational purposes.

All trademarks and brand names displayed on this website are used strictly in accordance with the provisions of the Trade Marks Act, 1999, specifically Sections 30 and 30(1) governing fair use. Trademark ownership has been accurately attributed under the "Manufacturer/ TM Owner" section in compliance with statutory requirements.

Ordering Process

Simple, Secure, and Seamless

Learn how our streamlined ordering process guarantees fast, compliant, and reliable access to essential medicines worldwide.

Quote request form

01

Submit Quote Request Form

Tell us what medications you need by filling out our simple form and uploading a valid document.

Price estimate review

02

We Review & Send Estimate

Our licensed pharmacists will verify your details and provide you with a detailed cost estimate.

Secure payment

03

Confirm & Make Payment

Discuss any queries, approve the estimate, and complete your payment.

Worldwide delivery

04

Get Delivered

Your medicines, safely packed and delivered to your door or nearest airport — hassle-free.

Quality You Can Trust

Our internationally recognized certifications underscore our commitment to safety, quality, and excellence.