Product image of Igixon (Desogestrel, Ethinylestradiol) supplied by GNH India

Igixon

Active Ingredient:
Desogestrel, Ethinylestradiol
Origin:
EU

Igixon (Desogestrel, Ethinylestradiol)

Desogestrel, the active ingredient in Igixon, is a combined oral contraceptive presented as an oral tablet for oral administration. Together with ethinylestradiol, it provides hormonal regulation that prevents ovulation and creates cervical mucus changes, offering reliable contraception for women of reproductive age seeking pregnancy prevention.

GNH India supplies Igixon as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide. The company adheres to stringent quality standards and provides regulatory documentation to support global distribution. Customers benefit from reliable supply chains and responsive technical support.

Manufacturer / TM Owner

Gedeon Richter Plc.

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Indications & Clinical Uses

  • Igixon, a combined oral contraceptive, acts on the hormonal regulation of the menstrual cycle to prevent pregnancy.
  • Contraception: prevents pregnancy by inhibiting ovulation and fertilization.
  • Menstrual cycle regulation: helps achieve more regular menstrual bleeding patterns.
  • Acne management: may improve acne associated with androgen excess.

How It Works

  • Desogestrel, a progestin, suppresses the mid‑cycle surge of luteinizing hormone, thereby inhibiting ovulation. Ethinylestradiol, a synthetic estrogen, stabilizes the endometrial lining and increases cervical mucus viscosity, creating an environment hostile to sperm. The combined hormonal effect prevents fertilization and reduces the likelihood of implantation.

Side Effects

Igixon may cause a range of adverse reactions, which are generally classified by frequency and severity.

Common Side Effects

  • Nausea
  • Breast tenderness
  • Headache
  • Weight gain
  • Mood changes
  • Spotting between periods

Serious or Rare Side Effects

  • Venous thromboembolism (deep‑vein thrombosis, pulmonary embolism)
  • Arterial thrombosis (stroke, myocardial infarction)
  • Severe hypertension
  • Liver dysfunction or cholestasis
  • Gallbladder disease (biliary colic, cholelithiasis)
  • Anaphylactic or severe allergic reaction

Precautions & Warnings

  • Before prescribing Igixon, clinicians should consider several precautionary measures to ensure safe use.
  • Pregnancy testing: confirm non‑pregnant status before initiating therapy.
  • Smoking: avoid in women over 35 who smoke due to increased thrombotic risk.
  • History of thromboembolism: assess for prior clotting disorders.
  • Liver disease: evaluate hepatic function prior to use.
  • Missed dose: follow specific guidance for missed tablets.
  • Store at ambient temperature: keep below 25 °C, protect from moisture and light.

Avoid Interactions

Igixon can interact with other medicines, altering its effectiveness or safety profile.

Major Interactions (Avoid)

  • Enzyme inducers (e.g., rifampin, carbamazepine, phenytoin) may markedly reduce contraceptive efficacy.
  • Anticoagulants (warfarin) may have unpredictable effects on clotting parameters.

Moderate Interactions (Monitor Closely)

  • Antifungal agents (ketoconazole, itraconazole) can increase hormone levels, requiring monitoring.
  • SSRIs (fluoxetine, sertraline) may increase bleeding risk.
  • Herbal supplements (St. John’s wort) may lower contraceptive effectiveness.

Frequently Asked Questions

Igixon is a combined oral contraceptive containing desogestrel and ethinylestradiol. It is prescribed to prevent pregnancy in women of reproductive age by suppressing ovulation and altering cervical mucus. It may also be used to regulate menstrual cycles and treat hormone‑related acne, depending on clinical judgment.

Desogestrel is a progestin that inhibits the mid‑cycle surge of luteinizing hormone, preventing ovulation. Ethinylestradiol is a synthetic estrogen that stabilizes the endometrial lining and thickens cervical mucus, making it hostile to sperm. Together they create hormonal conditions that block fertilization and implantation.

The dosing regimen for Igixon is determined by the prescribing clinician. Typically, combined oral contraceptives are taken as one tablet daily for 21 or 24 days followed by a hormone‑free interval, but the exact schedule, tablet strength and any break days must be set by the healthcare provider based on the product label and patient needs.

Igixon is contraindicated during pregnancy because its purpose is to prevent conception. If pregnancy occurs, the product should be discontinued. Limited data are available for breastfeeding; combined oral contraceptives are generally considered compatible with lactation, but clinicians should evaluate individual risk‑benefit and discuss with the patient.

To place an order, submit an enquiry on the Igixon product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including any temperature requirements) and the necessary import documentation.

Igixon contains desogestrel, a third‑generation progestin, combined with ethinylestradiol, which may offer a lower risk of androgenic side effects such as acne compared with older progestins. Efficacy in preventing pregnancy is comparable to other approved combined pills, while the side‑effect profile may differ slightly, especially regarding weight gain and lipid changes.

Igixon tablets should be stored at ambient temperature, below 25 °C, in their original blister pack to protect from moisture and light. Keep the medication out of reach of children and do not use tablets that are discolored, broken or past the expiration date.

Igixon is taken orally, usually once daily at the same time each day, with or without food. The typical regimen involves a series of active tablets followed by a hormone‑free interval, after which a new pack is started. Patients should follow the specific instructions provided by their prescriber or the product labeling.

The most serious risks include venous thromboembolism, arterial thrombosis such as stroke or myocardial infarction, and severe hypertension. These events are rare but can be life‑threatening, especially in women who smoke, are over 35, or have a history of clotting disorders. Prompt medical attention is required if symptoms of blood clots appear.

Igixon is contraindicated in women who are pregnant, have known or suspected breast cancer, have a history of thromboembolic disease, uncontrolled hypertension, severe liver disease, or are smokers over the age of 35. It should also be avoided in individuals with known hypersensitivity to desogestrel, ethinylestradiol or any excipients in the tablet.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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