Product image of Ikelan (Atenolol) supplied by GNH India

Ikelan

Active Ingredient:
Atenolol
Origin:
EU

Ikelan (Atenolol)

Atenolol, the active ingredient in Ikelan, is a beta blocker presented as an oral dosage form for oral use. It is used to manage high blood pressure, chest pain, and certain heart rhythm disorders in adult patients.
GNH India supplies Ikelan as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Medochemie Ltd.

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Indications & Clinical Uses

Atenolol is employed in cardiovascular conditions that require reduction of heart workload and blood pressure.

  • Hypertension: lowers systolic and diastolic pressure to reduce cardiovascular risk.
  • Angina pectoris: decreases myocardial oxygen demand, relieving chest pain.
  • Post‑myocardial infarction: helps prevent recurrent cardiac events by stabilising heart rate.
  • Cardiac arrhythmias: controls abnormal heart rhythms by slowing conduction through the AV node.

How It Works

  • Atenolol selectively blocks β1‑adrenergic receptors in the heart, reducing sympathetic stimulation. This leads to a decrease in heart rate, myocardial contractility, and cardiac output, which together lower arterial blood pressure and diminish the heart's oxygen demand.

Side Effects

Atenolol may cause a range of adverse reactions, from mild to severe.

Common Side Effects

  • Fatigue: feeling of tiredness or lack of energy.
  • Dizziness: light‑headed sensation, especially when standing quickly.
  • Cold extremities: reduced blood flow to hands and feet.
  • Bradycardia: slower than normal heart rate.
  • Gastrointestinal upset: nausea or mild abdominal discomfort.
  • Sleep disturbances: difficulty falling or staying asleep.

Serious or Rare Side Effects

  • Severe bradycardia: markedly slow heart rate requiring medical attention.
  • Heart block: impaired electrical conduction that can cause fainting.
  • Bronchospasm: tightening of airway muscles, particularly in patients with asthma.
  • Masked hypoglycemia: reduced warning signs of low blood sugar in diabetic patients.
  • Severe hypotension: dangerously low blood pressure leading to dizziness or shock.
  • Allergic reactions: rash, itching, swelling, or anaphylaxis.

Precautions & Warnings

Before initiating atenolol therapy, consider the following safety measures.

  • Renal impairment: adjust dose or monitor renal function closely.
  • Hepatic impairment: use with caution and consider dose reduction.
  • Asthma or COPD: monitor for bronchospasm and respiratory difficulty.
  • Pregnancy Category D: avoid unless potential benefits outweigh risks.
  • Concomitant beta‑blockers: avoid additive cardiac depression.
  • Store at ambient temperature: keep in original container, protect from moisture and light.

Avoid Interactions

Atenolol can interact with several medicines, requiring careful management.

Major Interactions (Avoid)

  • Verapamil or diltiazem: may cause severe bradycardia or heart block.
  • Clonidine: abrupt discontinuation can trigger rebound hypertension.
  • Insulin or sulfonylureas: may mask symptoms of hypoglycemia.

Moderate Interactions (Monitor Closely)

  • Other antihypertensives: combined effect may lead to excessive blood pressure reduction.
  • NSAIDs: can diminish atenolol’s blood‑pressure‑lowering efficacy.

Frequently Asked Questions

Ikelan contains atenolol, a beta‑blocker that is prescribed to treat high blood pressure, chest pain (angina), to reduce the risk of further heart attacks after a myocardial infarction, and to manage certain cardiac arrhythmias by slowing the heart rate.

Atenolol selectively blocks β1‑adrenergic receptors in the heart, decreasing sympathetic stimulation. This reduces heart rate, contractility, and cardiac output, which together lower arterial pressure and lessen the heart’s oxygen demand.

The appropriate dose of Ikelan is determined by the prescribing clinician based on the patient’s medical condition, age, renal function, and response to therapy. Dosage adjustments are made individually and should follow the prescriber’s instructions.

Atenolol is classified as Pregnancy Category D, indicating potential risk to the fetus. It should be avoided unless the therapeutic benefit justifies the risk. Limited data are available for breastfeeding, and a healthcare professional should assess safety before use.

To place an order, submit an enquiry on the product page at gnhindia.com specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Atenolol is a selective β1‑blocker, offering heart‑rate control and reduced cardiac output. Compared with ACE inhibitors or calcium‑channel blockers, it may be preferred in patients with a history of myocardial infarction or angina, but it can cause fatigue and may be less effective in isolated hypertension without a cardiac component.

Ikelan should be stored at ambient temperature, preferably below 25 °C. Keep the product in its original packaging, protect it from moisture and direct sunlight, and ensure the container is tightly closed to maintain stability.

Ikelan is taken orally, usually with or without food, as directed by the prescriber. The tablet should be swallowed whole with a glass of water and not chewed or crushed unless specifically instructed.

Serious risks include severe bradycardia, heart block, marked hypotension, bronchospasm in patients with asthma or COPD, and masking of hypoglycemia symptoms in diabetic patients. Prompt medical attention is required if any of these events occur.

Atenolol is contraindicated in patients with severe sinus bradycardia, second‑ or third‑degree atrioventricular block, overt heart failure, and in individuals with known hypersensitivity to the drug. Caution is also advised for patients with uncontrolled asthma, severe peripheral vascular disease, or those taking certain interacting medications.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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