Product image of Ilmodol Dolori Articolari E Muscolari (Diclofenac Epolamine) supplied by GNH India

Ilmodol Dolori Articolari E Muscolari

Active Ingredient:
Diclofenac Epolamine
Origin:
EU

Ilmodol Dolori Articolari E Muscolari (Diclofenac Epolamine)

Diclofenac epolamine, the active ingredient in Ilmodol Dolori Articolari E Muscolari, is a nonsteroidal anti‑inflammatory drug (NSAID) presented as a topical formulation for external use. It relieves joint, muscle and arthritic pain in adult patients, reducing inflammation at the site of application.

GNH India supplies Ilmodol Dolori Articolari E Muscolari as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Farmitalia S.R.L.

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Indications & Clinical Uses

Diclofenac epolamine is a topical NSAID used to manage pain and inflammation in musculoskeletal conditions.

  • Joint (articular) pain: reduces inflammation and alleviates discomfort in affected joints.
  • Muscle pain: eases soreness and stiffness in strained or over‑used muscles.
  • Arthritic pain: diminishes swelling and pain associated with osteoarthritis and rheumatoid arthritis.

How It Works

  • Diclofenac epolamine inhibits cyclooxygenase‑1 and cyclooxygenase‑2 enzymes in peripheral tissues, decreasing the synthesis of prostaglandins that mediate inflammation, pain and fever. By limiting prostaglandin production at the site of application, it provides localized anti‑inflammatory and analgesic effects without significant systemic exposure.

Side Effects

Topical diclofenac may cause skin‑related reactions and, rarely, systemic adverse events.

Common Side Effects

  • Skin irritation: redness, itching or burning at the application site.
  • Dryness or peeling of the skin.
  • Localized rash or mild swelling.

Serious or Rare Side Effects

  • Severe allergic reactions: hives, angioedema, or anaphylaxis.
  • Stevens‑Johnson syndrome or toxic epidermal necrolysis.
  • Systemic NSAID effects: gastrointestinal bleeding, renal impairment, or cardiovascular events.

Precautions & Warnings

When using Ilmodol, consider the following safety measures.

  • Assess skin integrity: avoid application on broken, infected or inflamed skin.
  • Limit area of application: do not exceed the recommended surface area per dose.
  • Monitor for systemic signs: watch for unexplained stomach pain, blood in stool, or swelling.
  • Use with caution in elderly: increased susceptibility to NSAID‑related adverse events.
  • Avoid concurrent systemic NSAIDs: higher risk of gastrointestinal and renal complications.
  • Store at room temperature: keep in the original container, protect from moisture and direct sunlight.

Avoid Interactions

Diclofenac epolamine may interact with other medicines, altering safety or efficacy.

Major Interactions (Avoid)

  • Systemic NSAIDs: increased risk of gastrointestinal bleeding and renal toxicity.
  • Anticoagulants (e.g., warfarin): heightened bleeding tendency.
  • Lithium: potential for elevated lithium serum levels.
  • Methotrexate: enhanced methotrexate toxicity.
  • Other COX‑2 inhibitors: additive cardiovascular risk.

Moderate Interactions (Monitor Closely):\n- Diuretics: possible reduction in renal function.

  • ACE inhibitors or ARBs: may impair renal perfusion.
  • Corticosteroids: increased gastrointestinal ulcer risk.
  • SSRIs or SNRIs: additive bleeding risk.
  • Antihypertensives (especially potassium‑sparing): monitor electrolytes.

Frequently Asked Questions

Ilmodol Dolori Articolari E Muscolari is a topical formulation containing diclofenac epolamine. It is indicated for the relief of joint (articular) pain, muscle pain and arthritic pain, helping to reduce inflammation and discomfort in the affected areas.

Diclofenac epolamine works by inhibiting the cyclooxygenase‑1 and cyclooxygenase‑2 (COX‑1 and COX‑2) enzymes in peripheral tissues. This inhibition lowers prostaglandin production, which are mediators of inflammation and pain, thereby providing localized anti‑inflammatory and analgesic effects when applied to the skin.

The appropriate dose of Ilmodol Dolori Articolari E Muscolari is determined by the prescribing healthcare professional. The prescriber will consider the severity of pain, the size of the area to be treated and any relevant patient factors before recommending the amount and frequency of application.

Safety of topical diclofenac during pregnancy or lactation has not been definitively established. Healthcare providers generally advise caution and may recommend alternative therapies, especially in the first trimester or when breastfeeding, to avoid potential risks to the fetus or infant.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including any cold‑chain requirements) and necessary import documentation.

Ilmodol contains diclofenac epolamine, a potent NSAID that offers rapid skin penetration and strong anti‑inflammatory activity. Compared with other topical NSAIDs such as ibuprofen or ketoprofen gels, diclofenac epolamine often provides quicker onset of pain relief, though individual response and tolerability may vary.

Ilmodol should be stored at room temperature, ideally below 25 °C. Keep the product in its original packaging, protect it from moisture and direct sunlight, and ensure the container is tightly closed when not in use to maintain stability.

The gel or cream is applied to clean, dry skin over the painful area. A thin layer is spread gently and massaged until fully absorbed. The exact amount and frequency should follow the prescribing clinician’s instructions, typically not exceeding the recommended surface area per dose.

Serious risks, though rare, include severe allergic reactions such as anaphylaxis, Stevens‑Johnson syndrome or toxic epidermal necrolysis, and systemic NSAID effects like gastrointestinal bleeding, renal impairment, or cardiovascular events. Patients should seek immediate medical attention if they notice signs of a serious reaction.

Ilmodol should be avoided by individuals with known hypersensitivity to diclofenac, other NSAIDs, or any component of the formulation. It is also contraindicated on broken, infected or inflamed skin, and should be used with caution in patients with a history of gastrointestinal ulcers, renal disease, or cardiovascular disorders.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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