Product image of Ilomedin (Iloprost Trometamol) supplied by GNH India

Ilomedin

Active Ingredient:
Iloprost Trometamol
Origin:
EU

Ilomedin (Iloprost Trometamol)

Iloprost Trometamol, the active ingredient in Ilomedin, is a prostacyclin analog presented as a solution for injection for intravenous use. It treats pulmonary arterial hypertension and digital ulcers associated with systemic sclerosis in adult patients. Ilomedin is authorized in the European Union and is supplied as a sterile injectable solution.

GNH India supplies Ilomedin as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals and clinics worldwide.

Manufacturer / TM Owner

Bayer Hellas Sa

1
Pack/s
This product is added to your enquiry list

Request a Quote

Please fill out the form below and our team will get back to you shortly with pricing and further information.

A minimum order value applies. Our team will confirm the exact amount or quantity after reviewing your requirements.

Indications & Clinical Uses

  • Ilomedin is a prostacyclin analog that acts on the pulmonary vascular pathway to provide vasodilation and improve microcirculation.
  • Pulmonary arterial hypertension: improves functional class, exercise capacity and hemodynamic parameters.
  • Digital ulcers associated with systemic sclerosis: accelerates ulcer healing and reduces the formation of new ulcers.
  • Raynaud's phenomenon: decreases frequency and severity of vasospastic attacks.

How It Works

  • Iloprost Trometamol selectively activates the prostacyclin (IP) receptor on vascular smooth‑muscle cells, leading to increased cyclic AMP levels. This cascade causes potent vasodilation of pulmonary and systemic arteries, inhibits platelet aggregation, and improves endothelial function, thereby reducing pulmonary vascular resistance and supporting tissue perfusion.

Side Effects

Ilomedin may cause a range of adverse reactions, most of which are dose‑related and reversible.

Common Side Effects

  • Headache
  • Flushing
  • Nausea
  • Jaw pain or discomfort

Serious or Rare Side Effects

  • Severe hypotension
  • Pulmonary edema
  • Clinically significant bleeding events

Precautions & Warnings

  • When using Ilomedin, clinicians should consider several safety measures.
  • Monitor blood pressure: watch for hypotensive episodes during and after infusion.
  • Avoid use in recent major hemorrhage: increased bleeding risk.
  • Caution in heart failure: may exacerbate fluid overload.
  • Adjust in renal impairment: dose titration may be required.
  • Contraindicated in known hypersensitivity to iloprost or formulation components.
  • Store at 2-8°C: keep refrigerated, protect from light, do not freeze or shake.

Avoid Interactions

Ilomedin can interact with other medicines that affect vascular tone or coagulation.

Major Interactions (Avoid)

  • Concomitant nitrates or other potent vasodilators: risk of severe hypotension.
  • Anticoagulants (e.g., warfarin, heparin): heightened bleeding tendency.
  • Phosphodiesterase‑5 inhibitors: additive vasodilatory effect.

Moderate Interactions (Monitor Closely)

  • Calcium channel blockers: may modestly lower blood pressure.
  • Beta‑blockers: can mask tachycardia associated with hypotension.
  • NSAIDs: may affect renal function and fluid balance.

Frequently Asked Questions

Ilomedin is an injectable prostacyclin analog indicated for the treatment of pulmonary arterial hypertension and for the management of digital ulcers associated with systemic sclerosis. It helps lower pulmonary vascular resistance and promotes healing of ischemic skin lesions.

Iloprost Trometamol selectively binds to the IP (prostacyclin) receptor on vascular smooth‑muscle cells, raising intracellular cyclic AMP. This leads to vasodilation of pulmonary and systemic arteries, inhibition of platelet aggregation, and improved endothelial function, which together reduce pulmonary arterial pressure.

The dosing regimen for Ilomedin is individualized by the prescribing physician. It is typically started at a low infusion rate and titrated upward based on clinical response and tolerability, with adjustments made according to blood pressure and symptom control.

Safety data for Ilomedin during pregnancy and lactation are limited. It should only be used when the potential benefit to the mother outweighs any possible risk to the fetus or infant, and the decision must be made by the treating physician.

To order Ilomedin, submit an enquiry on the product page at gnhindia.com indicating the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including cold‑chain if needed) and import documentation.

Ilomedin (iloprost) is a prostacyclin analog similar to epoprostenol and treprostinil. Compared with epoprostenol, iloprost has a longer half‑life and can be administered via intermittent IV infusion rather than continuous infusion, offering more flexibility. All share vasodilatory and antiplatelet effects but differ in administration routes and stability.

Ilomedin must be stored refrigerated at 2‑8 °C, protected from light, and must never be frozen or shaken. The solution should be kept in its original container until use, and any unused portion should be discarded according to local regulations.

Ilomedin is supplied as a sterile solution for injection and is administered intravenously. It is usually given as a continuous infusion over a defined period, with the rate adjusted by the clinician based on patient response and tolerability.

The most serious adverse events include severe hypotension, pulmonary edema, and significant bleeding. Patients should be monitored closely for sudden drops in blood pressure, respiratory distress, or signs of hemorrhage during and after infusion.

Ilomedin is contraindicated in patients with known hypersensitivity to iloprost or any component of the formulation, and it should be avoided in individuals with recent major bleeding, uncontrolled severe heart failure, or severe hypotension.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

Disclaimer

At GNH India, we aim to provide information that is expert-reviewed, accurate, and reliable. However, all content on this platform is intended for general informational purposes only and does not constitute professional medical advice, diagnosis, or treatment. While efforts are made to maintain accuracy and currency, the information may contain errors, omissions, or may not reflect the latest developments. Always consult a qualified healthcare professional regarding any medical concerns.

All product names, brand names, trademarks and registered trademarks displayed on this website are the property of their respective owners. This website and its operator are not affiliated with, endorsed by, or authorized by any such trade mark owners unless expressly stated. Any reference to product names or trademarks is made solely for descriptive and informational purposes. No commercial relationship, sponsorship, approval, or association with any trademark owner should be inferred. Information provided herein does not constitute promotion, advertising, or an offer for sale of any medicinal product and is intended solely for general informational purposes.

All trademarks and brand names displayed on this website are used strictly in accordance with the provisions of the Trade Marks Act, 1999, specifically Sections 30 and 30(1) governing fair use. Trademark ownership has been accurately attributed under the "Manufacturer/ TM Owner" section in compliance with statutory requirements.

Ordering Process

Simple, Secure, and Seamless

Learn how our streamlined ordering process guarantees fast, compliant, and reliable access to essential medicines worldwide.

Quote request form

01

Submit Quote Request Form

Tell us what medications you need by filling out our simple form and uploading a valid document.

Price estimate review

02

We Review & Send Estimate

Our licensed pharmacists will verify your details and provide you with a detailed cost estimate.

Secure payment

03

Confirm & Make Payment

Discuss any queries, approve the estimate, and complete your payment.

Worldwide delivery

04

Get Delivered

Your medicines, safely packed and delivered to your door or nearest airport — hassle-free.

Quality You Can Trust

Our internationally recognized certifications underscore our commitment to safety, quality, and excellence.