Product image of Iloxen (Pseudoephedrine Hydrochloride, Ibuprofen) supplied by GNH India

Iloxen

Active Ingredient:
Pseudoephedrine Hydrochloride, Ibuprofen
Origin:
EU

Iloxen (Pseudoephedrine Hydrochloride, Ibuprofen)

Pseudoephedrine Hydrochloride and ibuprofen, the active ingredients in Iloxen, are a sympathomimetic decongestant and a nonsteroidal anti‑inflammatory drug presented as an oral tablet for systemic use. They relieve nasal congestion, pain, fever and inflammation in adults.
GNH India supplies Iloxen as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Pharmaswiss Česká Republika S.R.O.

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Indications & Clinical Uses

Iloxen combines a decongestant and an NSAID to treat conditions involving the upper respiratory tract and musculoskeletal discomfort.

  • Nasal congestion: reduces swelling of nasal mucosa and improves airflow.
  • Headache: alleviates tension‑type or sinus‑related headache pain.
  • Fever: lowers elevated body temperature.
  • General pain: provides relief from mild to moderate aches such as toothache or muscle soreness.

How It Works

  • Pseudoephedrine hydrochloride acts as an alpha‑adrenergic agonist, causing vasoconstriction of the nasal mucosa and decreasing edema. Ibuprofen inhibits cyclooxygenase‑1 and cyclooxygenase‑2 enzymes, reducing prostaglandin synthesis, which leads to analgesic, antipyretic and anti‑inflammatory effects throughout the body.

Side Effects

Iloxen may cause a range of adverse reactions, most of which are mild and transient.

Common Side Effects

  • Dry mouth: sensation of reduced salivation.
  • Insomnia: difficulty falling or staying asleep.
  • Nausea: mild stomach upset.
  • Dizziness: light‑headed feeling.
  • Headache: mild to moderate pain.
  • Gastrointestinal discomfort: mild abdominal pain or heartburn.

Serious or Rare Side Effects

  • Hypertension: significant increase in blood pressure.
  • Cardiac arrhythmia: irregular heart rhythm.
  • Severe allergic reaction: rash, swelling, or breathing difficulty.
  • Gastrointestinal bleeding: black stools or vomiting blood.
  • Liver dysfunction: jaundice or abnormal liver tests.
  • Renal impairment: reduced urine output or swelling.

Precautions & Warnings

Before using Iloxen, consider the following safety measures.

  • Cardiovascular disease: avoid if you have uncontrolled hypertension or heart disease.
  • Pregnancy and breastfeeding: consult a healthcare professional before use.
  • Drug allergies: do not take if you are allergic to pseudoephedrine, ibuprofen or related compounds.
  • Existing medical conditions: inform your doctor of asthma, diabetes, glaucoma or thyroid disorders.
  • Concomitant medications: review all current medicines with a pharmacist.
  • Store at ambient temperature: keep below 25 °C, in the original packaging, protected from moisture and direct sunlight.

Avoid Interactions

Iloxen can interact with several medicines; awareness helps prevent adverse outcomes.

Major Interactions (Avoid)

  • Monoamine oxidase inhibitors (MAOIs): risk of hypertensive crisis.
  • Anticoagulants (e.g., warfarin): increased bleeding risk.
  • Other NSAIDs or corticosteroids: heightened gastrointestinal toxicity.

Moderate Interactions (Monitor Closely)

  • Antihypertensives: pseudoephedrine may reduce their effectiveness.
  • Diuretics: potential for electrolyte imbalance.
  • Lithium: pseudoephedrine may raise lithium levels.
  • Antidepressants (SSRIs, SNRIs): possible increase in serotonergic effects.

Frequently Asked Questions

Iloxen is indicated for relief of nasal congestion, reduction of fever, and alleviation of mild to moderate pain such as headache, toothache, or muscle aches. It combines a decongestant with an anti‑inflammatory analgesic to address both upper‑respiratory symptoms and general discomfort.

Pseudoephedrine hydrochloride stimulates alpha‑adrenergic receptors in the nasal mucosa, causing blood‑vessel constriction. This vasoconstriction reduces swelling and excess mucus, thereby improving airflow and easing congestion.

The appropriate dose of Iloxen is determined by a qualified prescriber based on the patient’s age, weight, medical history and the severity of symptoms. Patients should follow the healthcare professional’s instructions and not exceed the recommended amount.

Pregnancy and breastfeeding considerations should be discussed with a healthcare provider. Pseudoephedrine and ibuprofen cross the placenta and may be present in breast milk, so a doctor will weigh potential benefits against possible risks before recommending use.

To place an order, submit an enquiry on the Iloxen product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Iloxen offers a fixed‑dose combination of pseudoephedrine and ibuprofen, providing both rapid decongestion and anti‑inflammatory pain relief. Compared with separate products, it simplifies dosing and may improve adherence, while delivering comparable efficacy to other combination therapies that pair a sympathomimetic with an NSAID.

Iloxen should be stored at ambient temperature, preferably below 25 °C. Keep the tablets in their original blister pack or container, protect them from moisture, heat and direct sunlight to maintain potency and stability.

Iloxen is taken orally, usually with a full glass of water. The tablet should be swallowed whole and not chewed or crushed, unless a healthcare professional advises otherwise.

Serious risks include significant elevation of blood pressure, cardiac arrhythmias, severe allergic reactions, gastrointestinal bleeding, liver dysfunction and renal impairment. Patients experiencing any of these symptoms should seek immediate medical attention.

Iloxen is contraindicated for individuals with known hypersensitivity to pseudoephedrine, ibuprofen or any excipients, those with uncontrolled hypertension, severe coronary artery disease, active peptic ulcer disease, or who are taking monoamine oxidase inhibitors. Pregnant or breastfeeding women should only use it under medical supervision.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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