Product image of Iluvien (Fluocinolone Acetonide) supplied by GNH India

Iluvien

Active Ingredient:
Fluocinolone Acetonide
Origin:
EU

Iluvien (Fluocinolone Acetonide)

Fluocinolone Acetonide, the active ingredient in Iluvien, is a corticosteroid presented as a 0.19 mg intravitreal sustained‑release implant for intravitreal use. It treats diabetic macular edema and chronic non‑infectious posterior uveitis in adult patients.

GNH India supplies Iluvien as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals and clinics worldwide.

Manufacturer / TM Owner

Alimera Sciences Europe Limited

1
Pack/s
This product is added to your enquiry list

Request a Quote

Please fill out the form below and our team will get back to you shortly with pricing and further information.

A minimum order value applies. Our team will confirm the exact amount or quantity after reviewing your requirements.

Indications & Clinical Uses

  • Iluvien (fluocinolone acetonide) is used to manage ocular inflammatory conditions and retinal edema.
  • Diabetic macular edema: reduces retinal swelling and improves visual acuity.
  • Chronic non‑infectious posterior uveitis: controls intra‑ocular inflammation and prevents vision loss.
  • Uveitis‑associated macular edema: helps resolve swelling linked to intra‑ocular inflammation.

How It Works

  • Fluocinolone acetonide binds intracellular glucocorticoid receptors, altering gene transcription to suppress pro‑inflammatory cytokines, inhibit angiogenic factors, and stabilize the blood‑retinal barrier, thereby providing anti‑inflammatory, anti‑angiogenic, and immunosuppressive effects within the retina.

Side Effects

Adverse ocular reactions may occur following Iluvien implantation.

Common Side Effects

  • Increased intraocular pressure: may require topical therapy.
  • Cataract formation: accelerated lens opacity in phakic eyes.
  • Blurred vision: transient visual disturbance after insertion.
  • Vitreous floaters: perception of moving spots.

Serious or Rare Side Effects

  • Endophthalmitis: intraocular infection requiring urgent treatment.
  • Retinal detachment: separation of retinal layers.
  • Persistent elevated IOP needing surgical intervention.
  • Implant migration: displacement of the device within the eye.

Precautions & Warnings

  • Prior to Iluvien implantation, clinicians should evaluate ocular health and systemic factors.
  • Patient selection: assess glaucoma risk and baseline intraocular pressure.
  • Infection risk: avoid use in active ocular infection.
  • Pregnancy: safety unknown; use only if benefit outweighs potential risk.
  • Concurrent systemic steroids: consider additive immunosuppressive effects.
  • Monitor IOP: schedule regular ophthalmic examinations post‑implant.
  • Store at ambient temperature: keep in original packaging, protect from moisture and light.

Avoid Interactions

Fluocinolone acetonide implants may interact with other ocular or systemic therapies.

Major Interactions (Avoid)

  • Other intravitreal corticosteroids: additive risk of ocular hypertension.
  • Recent ocular surgery (within 6 weeks): increased wound‑healing complications.

Moderate Interactions (Monitor Closely)

  • Systemic CYP3A4 inhibitors (e.g., ketoconazole): may raise intraocular steroid levels.
  • Systemic immunosuppressants (e.g., cyclosporine): heightened infection risk.
  • Antiglaucoma medications: may require dosage adjustment.

Frequently Asked Questions

Iluvien is an intravitreal sustained‑release implant containing fluocinolone acetonide. It is indicated for the treatment of diabetic macular edema and chronic non‑infectious posterior uveitis, helping to reduce retinal swelling and control intra‑ocular inflammation.

Fluocinolone acetonide binds to intracellular glucocorticoid receptors, modulating gene transcription. This suppresses pro‑inflammatory cytokines, reduces angiogenic factors, and stabilises the blood‑retinal barrier, providing anti‑inflammatory, anti‑angiogenic and immunosuppressive effects in the eye.

The implant contains a fixed 0.19 mg dose of fluocinolone acetonide that is released continuously over several months. The prescribing ophthalmologist determines whether the implant is appropriate for each patient; no separate dosing regimen is required.

Safety of Iluvien in pregnancy and lactation has not been established. It should be used only if the potential benefit justifies any possible risk to the fetus or infant, and the decision must be made by the treating physician.

Enquiries are submitted via the product page on gnhindia.com, where you specify the required quantity. GNH India supplies hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any required import documentation.

Iluvien provides a longer‑lasting release (up to 36 months) compared with dexamethasone‑based implants such as Ozurdex, which release drug over several months. This may reduce the frequency of re‑injection but requires careful monitoring for intra‑ocular pressure and cataract formation.

The Iluvien implant should be stored at ambient temperature, kept in its original sterile packaging, and protected from moisture and direct light until it is administered by a qualified ophthalmic surgeon.

Iluvien is inserted into the vitreous cavity of the eye through a single intravitreal injection performed by an experienced ophthalmic surgeon. The implant then releases fluocinolone acetonide slowly over an extended period.

Serious adverse events include endophthalmitis (eye infection), retinal detachment, persistent elevation of intra‑ocular pressure that may require surgery, and cataract development that can impair vision.

Iluvien is contraindicated in patients with active ocular infection, uncontrolled glaucoma, known hypersensitivity to fluocinolone acetonide or any component of the implant, and in those where the benefits of a sustained‑release steroid are outweighed by the risk of complications.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

Disclaimer

At GNH India, we aim to provide information that is expert-reviewed, accurate, and reliable. However, all content on this platform is intended for general informational purposes only and does not constitute professional medical advice, diagnosis, or treatment. While efforts are made to maintain accuracy and currency, the information may contain errors, omissions, or may not reflect the latest developments. Always consult a qualified healthcare professional regarding any medical concerns.

All product names, brand names, trademarks and registered trademarks displayed on this website are the property of their respective owners. This website and its operator are not affiliated with, endorsed by, or authorized by any such trade mark owners unless expressly stated. Any reference to product names or trademarks is made solely for descriptive and informational purposes. No commercial relationship, sponsorship, approval, or association with any trademark owner should be inferred. Information provided herein does not constitute promotion, advertising, or an offer for sale of any medicinal product and is intended solely for general informational purposes.

All trademarks and brand names displayed on this website are used strictly in accordance with the provisions of the Trade Marks Act, 1999, specifically Sections 30 and 30(1) governing fair use. Trademark ownership has been accurately attributed under the "Manufacturer/ TM Owner" section in compliance with statutory requirements.

Related Products

Other formulations containing Fluocinolone Acetonide

A

A
A

A
A

A
A

A

Browse all products →

Ordering Process

Simple, Secure, and Seamless

Learn how our streamlined ordering process guarantees fast, compliant, and reliable access to essential medicines worldwide.

Quote request form

01

Submit Quote Request Form

Tell us what medications you need by filling out our simple form and uploading a valid document.

Price estimate review

02

We Review & Send Estimate

Our licensed pharmacists will verify your details and provide you with a detailed cost estimate.

Secure payment

03

Confirm & Make Payment

Discuss any queries, approve the estimate, and complete your payment.

Worldwide delivery

04

Get Delivered

Your medicines, safely packed and delivered to your door or nearest airport — hassle-free.

Regulatory recognitions

Quality You Can Trust

Our internationally recognized certifications underscore our commitment to safety, quality, and excellence.

SGS GSDP Certification

GSDP Compliant from SGS

URS ISO 9001

URS ISO 9001 Certification

FDA Maharashtra

Licensed by FDA Maharashtra

IEC License DGFT

IEC License issued by DGFT