Product image of Imap (Fluspirilene) supplied by GNH India

Imap

Active Ingredient:
Fluspirilene
Origin:
EU

Imap (Fluspirilene)

Fluspirilene, the active ingredient in Imap, is a typical antipsychotic presented as an intramuscular injection for intramuscular use. It is indicated for the treatment of schizophrenia in adult patients and is marketed in the European Union.
GNH India supplies Imap as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Eumedica Pharmaceuticals Gmbh

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Indications & Clinical Uses

  • Fluspirilene is a typical antipsychotic that acts on dopaminergic pathways to manage psychotic disorders.
  • Schizophrenia: reduces positive and negative symptoms in adult patients.

How It Works

  • Fluspirilene exerts its therapeutic effect by competitively antagonising dopamine D2 receptors in the central nervous system. This blockade diminishes dopaminergic neurotransmission in mesolimbic pathways, thereby alleviating psychotic symptoms associated with schizophrenia.

Side Effects

Common Side Effects

  • Extrapyramidal symptoms (e.g., tremor, rigidity)
  • Sedation or drowsiness
  • Dry mouth
  • Constipation
  • Dizziness
  • Weight gain

Serious or Rare Side Effects

  • Neuroleptic malignant syndrome
  • Tardive dyskinesia
  • Agranulocytosis
  • Severe hypotension
  • Cardiac arrhythmias

Precautions & Warnings

Before initiating therapy, clinicians should consider the following precautions:

  • Monitor for extrapyramidal symptoms: assess motor function regularly.
  • Assess cardiovascular status: watch for hypotension or arrhythmias.
  • Avoid in patients with known hypersensitivity to fluspirilene or excipients.
  • Use caution in elderly patients with dementia-related psychosis: increased risk of mortality.
  • Do not discontinue abruptly: taper under medical supervision.
  • Store at 2-8°C: keep refrigerated, protect from light, do not freeze or shake.

Avoid Interactions

Fluspirilene may interact with several drug classes.

Major Interactions (Avoid)

  • MAO inhibitors: risk of severe hypotension.
  • Strong CYP2D6 inhibitors: increased plasma concentrations of fluspirilene.
  • Other dopamine antagonists: additive extrapyramidal effects.

Moderate Interactions (Monitor Closely)

  • Anticholinergic agents: may mask extrapyramidal symptoms.
  • Sedatives or hypnotics: enhanced central nervous system depression.
  • Alcohol: increased sedation and dizziness.

Frequently Asked Questions

Imap contains fluspirilene, a typical antipsychotic indicated for the management of schizophrenia in adult patients. It helps reduce both positive and negative psychotic symptoms.

Fluspirilene works by blocking dopamine D2 receptors in the brain, decreasing dopaminergic activity in pathways that are over‑active in schizophrenia, which leads to symptom improvement.

The dosage of Imap is determined by the prescribing clinician based on the patient’s clinical condition, response, and tolerability. Specific dosing regimens are not disclosed publicly.

Safety data for fluspirilene in pregnancy and lactation are limited. The drug should only be used if the potential benefit justifies any potential risk to the fetus or infant, and decisions should be made by a qualified healthcare professional.

To place an order, submit an enquiry on the Imap product page at gnhindia.com with the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including cold‑chain if needed) and import documentation.

Imap (fluspirilene) is a typical, first‑generation antipsychotic that primarily blocks dopamine D2 receptors, whereas many newer agents are atypical antipsychotics with broader receptor profiles and potentially lower risk of extrapyramidal side effects.

Imap should be stored at 2‑8 °C, kept refrigerated, protected from light, and must not be frozen or shaken. Maintain the original packaging to preserve stability.

Imap is supplied as an intramuscular injection. It is administered by a qualified healthcare professional into a suitable muscle, typically following aseptic technique and according to the prescriber’s instructions.

Serious risks include neuroleptic malignant syndrome, tardive dyskinesia, agranulocytosis, severe hypotension, and cardiac arrhythmias. Patients should be monitored closely for any signs of these conditions.

Imap is contraindicated in individuals with known hypersensitivity to fluspirilene or any of its excipients, and it should be used with caution in patients with severe cardiovascular disease, Parkinson’s disease, or a history of neuroleptic malignant syndrome.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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