Product image of Imazol Plus (Clotrimazole, Hexamidine Diisetionate) supplied by GNH India

Imazol Plus

Active Ingredient:
Clotrimazole, Hexamidine Diisetionate
Origin:
EU

Imazol Plus (Clotrimazole, Hexamidine Diisetionate)

Clotrimazole, the active ingredient in Imazol Plus, is an antifungal; Hexamidine diisetionate, also present, is an antiseptic presented as a topical formulation for skin use. It treats dermatophytosis, tinea pedis, tinea corporis and cutaneous candidiasis in adults and children and is suitable for over‑the‑counter use in many European markets.

GNH India supplies Imazol Plus as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide. The company adheres to stringent quality standards and provides regulatory‑approved batches for global distribution.

Manufacturer / TM Owner

Laboratoires Bailleul S.A.

1
Pack/s
This product is added to your enquiry list

Request a Quote

Please fill out the form below and our team will get back to you shortly with pricing and further information.

A minimum order value applies. Our team will confirm the exact amount or quantity after reviewing your requirements.

Indications & Clinical Uses

Imazol Plus combines an antifungal and antiseptic to treat superficial fungal infections of the skin.

  • Dermatophytosis: reduces fungal growth and relieves itching and scaling.
  • Tinea pedis: clears foot‑area infection and diminishes redness.
  • Tinea corporis: eliminates body‑area ringworm lesions.
  • Cutaneous candidiasis: eradicates yeast overgrowth on the skin.

How It Works

  • Clotrimazole inhibits the fungal enzyme lanosterol 14‑α‑demethylase, blocking ergosterol synthesis and compromising cell membrane integrity. Hexamidine diisetionate disrupts microbial cell membranes, leading to leakage of intracellular contents and providing broad‑spectrum antiseptic activity against bacteria and fungi.

Side Effects

Topical application of Imazol Plus may cause local skin reactions, ranging from mild irritation to rare severe hypersensitivity.

Common Side Effects

  • Burning sensation: transient discomfort at the application site.
  • Itching: mild pruritus may occur.
  • Redness: localized erythema.
  • Dryness: skin may feel less moist.
  • Irritation: mild stinging or tingling.
  • Contact dermatitis: mild allergic skin response.

Serious or Rare Side Effects

  • Severe allergic reaction: swelling, hives, or difficulty breathing.
  • Blistering or ulceration: extensive skin breakdown.
  • Stevens‑Johnson syndrome: rare but severe mucocutaneous eruption.
  • Systemic toxicity: unlikely but possible with extensive use.
  • Persistent rash: may indicate secondary infection.
  • Necrotizing fasciitis: extremely rare, requires immediate medical attention.

Precautions & Warnings

Before using Imazol Plus, consider the following safety measures.

  • Avoid application on broken skin: may increase irritation.
  • Do not use on mucous membranes: product not intended for oral or ocular use.
  • Limit use to recommended duration: prolonged use may lead to resistance.
  • Discontinue if severe irritation occurs: seek medical advice.
  • Pregnancy and lactation: consult a healthcare professional before use.
  • Store at room temperature: keep in the original container, protect from moisture and direct sunlight.

Avoid Interactions

Imazol Plus may interact with other topical agents; review the following categories.

Major Interactions (Avoid)

  • Concurrent use with other topical azole antifungals: risk of additive irritation.
  • Use with topical corticosteroids: may mask infection signs.
  • Systemic antifungal therapy: may increase systemic absorption (rare).

Moderate Interactions (Monitor Closely)

  • Co‑application with alcohol‑based moisturizers: may enhance burning.
  • Use with adhesive dressings: may trap product and increase irritation.
  • Concurrent use of other antiseptic agents: may cause cumulative skin dryness.

Frequently Asked Questions

Imazol Plus is indicated for the topical treatment of superficial fungal skin infections such as dermatophytosis, tinea pedis (athlete’s foot), tinea corporis (ringworm of the body) and cutaneous candidiasis caused by yeast overgrowth.

Clotrimazole inhibits the fungal enzyme lanosterol 14‑α‑demethylase, which blocks the synthesis of ergosterol, an essential component of fungal cell membranes, leading to loss of membrane integrity and fungal cell death.

The dosage of Imazol Plus is determined by the prescribing healthcare professional based on the specific infection, severity, patient age and treatment duration. Patients should follow the prescriber’s instructions and the product label.

Safety data for Imazol Plus in pregnancy and lactation are limited. Women who are pregnant, planning to become pregnant, or breastfeeding should discuss potential risks and benefits with their healthcare provider before using the product.

To order Imazol Plus, submit an enquiry on the product page at gnhindia.com specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and required import documentation.

Imazol Plus combines clotrimazole, a widely used azole antifungal, with hexamidine diisetionate, an antiseptic that adds antibacterial activity. This dual action can be advantageous over single‑agent antifungals when mixed bacterial‑fungal skin infections are suspected.

Store Imazol Plus at room temperature, preferably below 25 °C. Keep the product in its original packaging, protect it from moisture, excessive heat and direct sunlight to maintain stability and efficacy.

Imazol Plus is applied topically to the affected skin area. Clean and dry the area before use, then spread a thin layer of the product as directed by the prescriber, typically twice daily, and wash hands after application.

Serious risks, although rare, include severe allergic reactions such as swelling, hives, or difficulty breathing, and severe skin reactions like Stevens‑Johnson syndrome or extensive blistering. Immediate medical attention is required if these symptoms occur.

Imazol Plus should not be used by individuals with known hypersensitivity to clotrimazole, hexamidine diisetionate or any excipients in the formulation. It is also contraindicated on broken skin, mucous membranes, or in patients with severe liver disease without medical supervision.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

Disclaimer

At GNH India, we aim to provide information that is expert-reviewed, accurate, and reliable. However, all content on this platform is intended for general informational purposes only and does not constitute professional medical advice, diagnosis, or treatment. While efforts are made to maintain accuracy and currency, the information may contain errors, omissions, or may not reflect the latest developments. Always consult a qualified healthcare professional regarding any medical concerns.

All product names, brand names, trademarks and registered trademarks displayed on this website are the property of their respective owners. This website and its operator are not affiliated with, endorsed by, or authorized by any such trade mark owners unless expressly stated. Any reference to product names or trademarks is made solely for descriptive and informational purposes. No commercial relationship, sponsorship, approval, or association with any trademark owner should be inferred. Information provided herein does not constitute promotion, advertising, or an offer for sale of any medicinal product and is intended solely for general informational purposes.

All trademarks and brand names displayed on this website are used strictly in accordance with the provisions of the Trade Marks Act, 1999, specifically Sections 30 and 30(1) governing fair use. Trademark ownership has been accurately attributed under the "Manufacturer/ TM Owner" section in compliance with statutory requirements.

Related Products

Other formulations containing Clotrimazole, Hexamidine Diisetionate

A

A
A

A
A

A
A

A

Browse all products →

Ordering Process

Simple, Secure, and Seamless

Learn how our streamlined ordering process guarantees fast, compliant, and reliable access to essential medicines worldwide.

Quote request form

01

Submit Quote Request Form

Tell us what medications you need by filling out our simple form and uploading a valid document.

Price estimate review

02

We Review & Send Estimate

Our licensed pharmacists will verify your details and provide you with a detailed cost estimate.

Secure payment

03

Confirm & Make Payment

Discuss any queries, approve the estimate, and complete your payment.

Worldwide delivery

04

Get Delivered

Your medicines, safely packed and delivered to your door or nearest airport — hassle-free.

Regulatory recognitions

Quality You Can Trust

Our internationally recognized certifications underscore our commitment to safety, quality, and excellence.

SGS GSDP Certification

GSDP Compliant from SGS

URS ISO 9001

URS ISO 9001 Certification

FDA Maharashtra

Licensed by FDA Maharashtra

IEC License DGFT

IEC License issued by DGFT