Product image of Imidin N (Xylometazoline Hydrochloride) supplied by GNH India

Imidin N

Active Ingredient:
Xylometazoline Hydrochloride
Origin:
EU

Imidin N (Xylometazoline Hydrochloride)

Xylometazoline Hydrochloride, the active ingredient in Imidin N, is an alpha‑adrenergic agonist presented as a nasal spray for topical nasal use. It relieves nasal congestion associated with the common cold, allergic rhinitis and sinusitis in adults and children.

GNH India supplies Imidin N as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Sia Ingen Pharma

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Indications & Clinical Uses

Xylometazoline Hydrochloride is used to treat nasal congestion by acting on the nasal mucosa.

  • Common cold: reduces nasal blockage and improves airflow.
  • Allergic rhinitis: alleviates congestion caused by allergic inflammation.
  • Sinusitis: diminishes swelling of nasal passages to ease sinus drainage.

How It Works

  • Xylometazoline Hydrochloride selectively stimulates alpha‑adrenergic receptors on the smooth muscle of nasal mucosal vessels. This activation causes vasoconstriction, leading to reduced blood flow, decreased edema, and consequently less nasal congestion.

Side Effects

Adverse reactions may occur with nasal administration of Xylometazoline Hydrochloride.

Common Side Effects

  • Nasal burning or stinging
  • Sneezing
  • Dryness of nasal mucosa
  • Headache

Serious or Rare Side Effects

  • Rebound congestion with prolonged use
  • Hypertension (rare)

Precautions & Warnings

When using Imidin N, consider the following safety measures.

  • Duration of use: limit to 3‑5 days to avoid rebound congestion.
  • Underlying conditions: avoid if the patient has severe hypertension or coronary artery disease.
  • Age restrictions: not recommended for children under 2 years without medical advice.
  • Concomitant nasal medications: do not combine with other vasoconstrictive nasal sprays.
  • Pregnancy and lactation: safety not established; use only if clearly needed.
  • Store at ambient temperature: keep below 25 °C, protect from moisture and direct sunlight, retain in the original container.

Avoid Interactions

Xylometazoline Hydrochloride may interact with other medicines.

Major Interactions (Avoid)

  • Monoamine oxidase inhibitors (MAOIs): may potentiate systemic vasoconstrictive effects.
  • Other nasal decongestants (e.g., phenylephrine, oxymetazoline): risk of excessive vasoconstriction.

Moderate Interactions (Monitor Closely)

  • Antihypertensive agents: monitor blood pressure as nasal vasoconstriction may affect systemic pressure.
  • Beta‑blockers: possible additive cardiovascular effects.
  • Tricyclic antidepressants: may increase risk of hypertension.

Frequently Asked Questions

Imidin N is an over‑the‑counter nasal spray that provides temporary relief of nasal congestion caused by the common cold, allergic rhinitis, and sinusitis. It works locally in the nasal passages to reduce swelling and improve airflow.

Xylometazoline Hydrochloride is a selective alpha‑adrenergic agonist. When applied to the nasal mucosa, it binds to alpha‑adrenergic receptors on blood‑vessel smooth muscle, causing vasoconstriction, which reduces mucosal edema and opens the nasal airway.

The exact dosing regimen is determined by the prescribing healthcare professional. Typically, a few sprays per nostril are used, not exceeding the recommended maximum daily frequency, and treatment should not extend beyond three to five days without medical advice.

Safety data for Xylometazoline Hydrochloride in pregnancy and lactation are limited. It should only be used if the potential benefit justifies any possible risk to the fetus or infant, and this decision must be made by a qualified healthcare provider.

To place an order, submit an enquiry on the Imidin N product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Imidin N contains Xylometazoline Hydrochloride, which has a similar vasoconstrictive profile to oxymetazoline but may have a slightly longer duration of action. Both are OTC nasal decongestants; choice often depends on local availability, patient tolerance and clinician preference.

Store the nasal spray at ambient temperature, preferably below 25 °C, in its original packaging. Protect it from moisture, direct sunlight, and extreme temperatures. Keep the container tightly closed when not in use to maintain product integrity.

Imidin N is administered as a nasal spray. The user gently inserts the tip into a nostril, blocks the opposite nostril, and sprays the recommended number of actuations while breathing in gently. The same procedure is repeated for the other nostril if required.

The most serious risks include rebound nasal congestion (rhinitis medicamentosa) after prolonged use and rare systemic effects such as elevated blood pressure. If these occur, discontinue use and seek medical attention promptly.

Imidin N should be avoided by individuals with severe hypertension, coronary artery disease, or known hypersensitivity to Xylometazoline Hydrochloride. Children under two years of age should not use the product unless directed by a healthcare professional.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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