Product image of Imigran Ftab (Sumatriptan) supplied by GNH India

Imigran Ftab

Active Ingredient:
Sumatriptan
Origin:
EU

Imigran Ftab (Sumatriptan)

Sumatriptan, the active ingredient in Imigran Ftab, is a selective serotonin (5‑HT1B/1D) receptor agonist presented as an oral tablet. It is classified as an acute migraine treatment and is used to relieve migraine attacks in adult patients. It is indicated for the rapid relief of migraine symptoms, including headache, nausea and sensitivity to light.

GNH India supplies Imigran Ftab as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide, providing reliable sourcing for acute migraine therapy. The company adheres to EU GMP standards and offers batch‑tested products with full regulatory documentation.

Manufacturer / TM Owner

Glaxosmithkline (Ireland) Limited

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Indications & Clinical Uses

  • Sumatriptan is a selective serotonin receptor agonist used for acute migraine management.
  • Migraine attacks: provides rapid relief of headache and associated nausea, photophobia, and phonophobia.
  • Migraine with aura: aborts migraine attack after aura onset.
  • Acute episodic migraine: reduces severity of migraine symptoms when taken at the first sign of an attack.

How It Works

  • Sumatriptan binds to 5‑HT1B and 5‑HT1D receptors on intracranial blood vessels and sensory nerve endings. Activation of 5‑HT1B receptors causes cranial vasoconstriction, while 5‑HT1D activation inhibits release of pro‑inflammatory neuropeptides such as CGRP, collectively reducing migraine pain and associated symptoms.

Side Effects

Common Side Effects

  • Chest discomfort or tightness
  • Flushing or warmth sensation
  • Nausea or abdominal pain
  • Dizziness or vertigo
  • Tingling or numbness in extremities
  • Fatigue or drowsiness

Serious or Rare Side Effects

  • Serotonin syndrome, especially with other serotonergic agents
  • Coronary artery vasospasm leading to chest pain
  • Ischemic stroke or transient ischemic attack
  • Severe hypertension or hypertensive crisis
  • Allergic reactions such as rash, angioedema, or anaphylaxis
  • Cardiac arrhythmias or myocardial infarction

Precautions & Warnings

  • Before initiating therapy, evaluate cardiovascular risk and medical history.
  • Medical assessment: assess for uncontrolled hypertension, ischemic heart disease, or cerebrovascular disorders.
  • Contraindications: avoid in patients with known hypersensitivity to sumatriptan or other triptans.
  • Drug interactions: review concomitant serotonergic medications to prevent serotonin syndrome.
  • Pregnancy and lactation: safety not established; use only if potential benefit outweighs risk.
  • Store at ambient temperature: keep in original container, protect from moisture and light.

Avoid Interactions

Sumatriptan may interact with several drug classes; review patient medication list.

Major Interactions (Avoid)

  • MAO inhibitors: increased risk of serotonin syndrome.
  • Ergot alkaloids: additive vasoconstriction may precipitate ischemia.
  • Other triptans: combined use can cause severe vasospasm.

Moderate Interactions (Monitor Closely)

  • SSRIs, SNRIs, or other serotonergic agents: monitor for serotonin syndrome.
  • Antihypertensive agents: may enhance hypotensive effects.
  • CYP3A4 inhibitors (e.g., ketoconazole): may raise sumatriptan plasma concentrations.

Frequently Asked Questions

Imigran Ftab is prescribed for the acute treatment of migraine attacks in adults. It helps to relieve headache pain and associated symptoms such as nausea, photophobia, and phonophobia when taken at the onset of a migraine episode.

Sumatriptan acts as an agonist at 5‑HT1B and 5‑HT1D receptors. Stimulation of 5‑HT1B receptors causes constriction of dilated cranial blood vessels, while activation of 5‑HT1D receptors inhibits release of inflammatory neuropeptides, together reducing migraine pain.

The dose of Imigran Ftab is individualized by a qualified prescriber based on the patient’s clinical condition, prior response, and tolerability. Physicians typically select an appropriate tablet strength and timing according to established migraine treatment guidelines.

Safety data for sumatriptan in pregnancy and lactation are limited, and the product is classified as having an unknown pregnancy category. It should only be used if the potential benefit justifies any possible risk to the fetus or infant, and under medical supervision.

To order Imigran Ftab, submit an enquiry on the product page at gnhindia.com specifying the required quantity. GNH India works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Imigran Ftab belongs to the triptan class, which provides rapid migraine relief through serotonin receptor activation. Compared with non‑triptan analgesics, triptans target the underlying vascular and neurogenic mechanisms of migraine, often resulting in faster and more complete symptom resolution.

Store Imigran Ftab at ambient temperature, preferably below 25 °C. Keep the tablets in the original blister pack, protect them from moisture and direct sunlight, and ensure the container is tightly closed to maintain product stability.

Imigran Ftab is taken orally with a full glass of water. The tablet should be swallowed whole and not chewed or crushed. It is usually taken at the first sign of a migraine attack, as directed by a healthcare professional.

Serious risks include serotonin syndrome when combined with other serotonergic drugs, coronary vasospasm leading to chest pain or myocardial ischemia, and rare cerebrovascular events such as stroke. Patients should seek immediate medical attention if they experience severe chest discomfort, sudden neurological changes, or signs of an allergic reaction.

Imigran Ftab is contraindicated in individuals with known hypersensitivity to sumatriptan or other triptans, uncontrolled hypertension, recent myocardial infarction or stroke, and certain severe cardiovascular disorders. It should also be avoided in patients taking monoamine oxidase inhibitors within the past two weeks.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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