Product image of Imigran Ftab (Sumatriptan) supplied by GNH India

Imigran Ftab

Active Ingredient:
Sumatriptan
Origin:
EU

Imigran Ftab (Sumatriptan)

Sumatriptan, the active ingredient in Imigran Ftab, is a Triptan presented as an oral tablet for the acute treatment of migraine attacks in adults. It works by targeting specific serotonin receptors to relieve headache pain.

GNH India supplies Imigran Ftab as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide, adhering to stringent quality standards and providing reliable global distribution with regulatory approvals across major markets.

Manufacturer / TM Owner

Glaxosmithkline B.V.

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Indications & Clinical Uses

  • Imigran Ftab (sumatriptan) is indicated for acute migraine management, acting on the trigeminovascular pathway.
  • Migraine (with or without aura): rapid relief of headache pain and associated symptoms.
  • Acute cluster headache: alleviation of severe unilateral head pain.
  • Migraine (without aura): reduction of headache intensity and associated nausea.

How It Works

  • Sumatriptan selectively agonises 5‑HT1B and 5‑HT1D receptors on intracranial blood vessels and trigeminal nerve terminals, causing cranial vasoconstriction and inhibition of neuropeptide release, which interrupts the transmission of pain signals within the trigeminovascular system.

Side Effects

Common Side Effects

  • Chest tightness or pressure
  • Tingling or numbness in the face or extremities
  • Warmth or flushing sensation
  • Nausea or abdominal discomfort
  • Dizziness or light‑headedness
  • Fatigue or drowsiness

Serious or Rare Side Effects

  • Coronary vasospasm or myocardial infarction
  • Severe hypertension or hypertensive crisis
  • Serotonin syndrome, especially with other serotonergic agents
  • Allergic reactions including rash, swelling, or anaphylaxis
  • Stroke or transient ischemic attack
  • Severe arrhythmias or cardiac arrest

Precautions & Warnings

Before using Imigran Ftab, consider the following precautions:

  • Cardiovascular disease: avoid use in patients with ischemic heart disease, angina, or prior myocardial infarction.
  • Uncontrolled hypertension: assess blood pressure and avoid if systolic >160 mmHg or diastolic >100 mmHg.
  • Serotonergic agents: monitor for signs of serotonin syndrome when combined with SSRIs, SNRIs, or MAO inhibitors.
  • Hemiplegic or basilar migraine: contraindicated due to increased vascular risk.
  • Use the lowest effective dose: follow prescriber guidance and do not exceed recommended frequency.
  • Store at ambient temperature: keep in the original container, protect from moisture and heat.

Avoid Interactions

Imigran Ftab may interact with several medicines. Consider the following:

Major Interactions (Avoid)

  • MAO inhibitors: risk of severe hypertension and serotonin syndrome.
  • Ergotamine or ergot derivatives: additive vasoconstriction may precipitate coronary events.
  • Other triptans: cumulative vasoconstrictive effect increases cardiovascular risk.

Moderate Interactions (Monitor Closely)

  • Antihypertensive agents: may enhance blood pressure‑lowering effects.
  • Oral contraceptives: possible increase in blood pressure; monitor regularly.
  • CYP3A4 inhibitors: may raise sumatriptan plasma levels, requiring dose adjustment.

Frequently Asked Questions

Imigran Ftab is prescribed for the acute treatment of migraine attacks in adults. It helps to relieve headache pain, throbbing, and associated symptoms such as nausea, photophobia, and phonophobia when taken at the onset of an attack.

Sumatriptan works by selectively stimulating 5‑HT1B and 5‑HT1D serotonin receptors in the brain. This action causes constriction of dilated cranial blood vessels and blocks the release of pain‑triggering neuropeptides, thereby interrupting migraine pain pathways.

The dose of Imigran Ftab is determined by a qualified prescriber based on individual patient needs and clinical response. Common tablet strengths include 25 mg, 50 mg, and 100 mg, but the exact regimen should follow the healthcare professional’s instructions.

Safety data for sumatriptan in pregnancy and lactation are limited. It should only be used if the potential benefit justifies any possible risk to the fetus or infant, and only under the guidance of a qualified healthcare provider.

To order Imigran Ftab, submit an enquiry on the product page at gnhindia.com specifying the required quantity. GNH India works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details, and any necessary import documentation.

Imigran Ftab belongs to the triptan class, which is generally more effective for moderate to severe migraine attacks than simple analgesics such as NSAIDs. Compared with other triptans, sumatriptan has a well‑established efficacy profile, but individual response and side‑effect tolerance may vary, making personalized selection important.

Imigran Ftab tablets should be stored at ambient temperature, below 25 °C, in their original packaging. Protect them from moisture, direct sunlight, and excessive heat to maintain product stability throughout its shelf life.

Imigran Ftab is taken orally as a whole tablet with a glass of water. It can be taken with or without food, but swallowing the tablet whole is recommended to ensure proper absorption and rapid onset of action.

Serious risks include coronary vasospasm, myocardial infarction, severe hypertension, serotonin syndrome (especially when combined with other serotonergic drugs), and rare cerebrovascular events such as stroke. Patients should seek immediate medical attention if they experience chest pain, severe headache, or any signs of an allergic reaction.

Imigran Ftab is contraindicated in patients with a history of ischemic heart disease, uncontrolled hypertension, previous stroke or transient ischemic attack, hemiplegic or basilar migraine, and in those taking MAO inhibitors within the past two weeks. It should also be avoided in individuals with known hypersensitivity to sumatriptan.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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