Product image of Imigran Radis (Sumatriptan) supplied by GNH India

Imigran Radis

Active Ingredient:
Sumatriptan
Origin:
EU

Imigran Radis (Sumatriptan)

Sumatriptan, the active ingredient in Imigran Radis, is a selective serotonin 5‑HT1B/1D receptor agonist presented as an oral tablet for oral use. It is indicated for the acute treatment of migraine attacks, with or without aura, in adult patients who require rapid symptom relief.

GNH India supplies Imigran Radis as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide, providing EU‑origin quality medicines and ensuring regulatory compliance and consistent product availability.

Manufacturer / TM Owner

Glaxosmithkline Pharma A/S

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Indications & Clinical Uses

  • Sumatriptan is a triptan class medication used to manage migraine disorders.
  • Migraine with aura: aborts acute attacks and reduces headache severity.
  • Migraine without aura: provides rapid relief of headache and associated symptoms.
  • Acute migraine attacks: stops progression of pain when taken at onset.

How It Works

  • Sumatriptan binds selectively to 5‑HT1B and 5‑HT1D receptors on intracranial blood vessels and sensory nerve terminals. Activation of these receptors causes cranial vasoconstriction and inhibits the release of pro‑inflammatory neuropeptides, thereby terminating migraine attacks and alleviating associated symptoms.

Side Effects

Common Side Effects

  • Chest pressure or tightness
  • Tingling or numbness in the face or extremities
  • Dizziness
  • Nausea

Serious or Rare Side Effects

  • Coronary vasospasm leading to chest pain
  • Severe allergic reaction (anaphylaxis)
  • Serotonin syndrome, especially with other serotonergic agents

Precautions & Warnings

Before initiating therapy, consider the following precautions:

  • Cardiovascular assessment: avoid use in patients with uncontrolled coronary artery disease.
  • Medication history: review for other serotonergic agents that may increase serotonin syndrome risk.
  • Age considerations: use caution in elderly patients due to heightened sensitivity.
  • Renal/hepatic function: adjust if severe impairment is present.
  • Pregnancy and lactation: discuss potential risks with the prescriber.
  • Store at ambient temperature: keep below 25 °C, protect from moisture and light.

Avoid Interactions

Sumatriptan may interact with several drug classes. Monitor patients accordingly.

Major Interactions (Avoid)

  • MAO inhibitors: increased risk of serotonin syndrome.
  • Ergot alkaloids: additive vasospasm risk.

Moderate Interactions (Monitor Closely)

  • SSRIs, SNRIs, or other serotonergic antidepressants: potential serotonin syndrome.
  • Tricyclic antidepressants: may enhance vasoconstrictive effects.
  • Antihypertensives: possible augmentation of blood pressure lowering.

Frequently Asked Questions

Imigran Radis contains sumatriptan and is prescribed for the acute treatment of migraine attacks, with or without aura, in adult patients. It is intended to relieve headache pain and associated symptoms when taken at the onset of a migraine episode.

Sumatriptan acts as an agonist at serotonin 5‑HT1B and 5‑HT1D receptors located on cranial blood vessels and sensory nerve endings. This activation causes vasoconstriction of dilated intracranial vessels and blocks the release of inflammatory neuropeptides, effectively aborting a migraine attack.

The specific dose of Imigran Radis is determined by the prescribing healthcare professional based on the individual’s clinical condition, response to therapy, and any relevant medical history. Patients should follow the prescriber’s instructions and not alter the dose without medical advice.

Safety data for sumatriptan in pregnancy and lactation are limited. The medication should only be used if the potential benefit justifies any possible risk to the fetus or infant. Women who are pregnant, planning pregnancy, or breastfeeding should discuss alternatives and risks with their prescriber.

To place an order, submit an enquiry on the Imigran Radis product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Imigran Radis belongs to the triptan class, which provides targeted serotonin receptor activation and rapid migraine relief. Compared with non‑specific analgesics such as NSAIDs, triptans like sumatriptan generally achieve faster and more complete headache resolution but require careful cardiovascular assessment before use.

Imigran Radis tablets should be stored at ambient temperature, preferably below 25 °C. Keep the product in its original packaging, protect it from moisture and direct light, and ensure the container is tightly closed to maintain stability throughout its shelf life.

Imigran Radis is taken orally as a whole tablet with a glass of water. It should be swallowed whole and not chewed or crushed. For optimal effect, the tablet is usually taken at the first sign of a migraine attack, as directed by the prescriber.

Serious adverse events include coronary vasospasm, which can cause chest pain, severe allergic reactions such as anaphylaxis, and serotonin syndrome when combined with other serotonergic drugs. Patients should seek immediate medical attention if they experience any of these symptoms.

Imigran Radis is contraindicated in patients with uncontrolled coronary artery disease, a history of myocardial infarction, severe peripheral vascular disease, uncontrolled hypertension, or known hypersensitivity to sumatriptan or any tablet excipients. It should also be avoided in individuals taking MAO inhibitors within the past two weeks.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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