Product image of Imigran Radis (Sumatriptan) supplied by GNH India

Imigran Radis

Active Ingredient:
Sumatriptan
Origin:
EU

Imigran Radis (Sumatriptan)

Sumatriptan, the active ingredient in Imigran Radis, is a serotonin (5‑HT1) receptor agonist presented as a tablet for oral use. It provides acute treatment of migraine attacks in adults.

GNH India supplies Imigran Radis as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Glaxosmithkline As

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Indications & Clinical Uses

Imigran Radis (sumatriptan) belongs to the serotonin receptor agonist class used for migraine management.

  • Migraine (acute treatment): Relieves headache pain and associated symptoms when taken at the onset of an attack.

How It Works

  • Sumatriptan selectively activates 5‑HT1B and 5‑HT1D receptors on cranial blood vessels and trigeminal nerve terminals. This action causes vasoconstriction of dilated intracranial arteries and inhibits release of pro‑inflammatory neuropeptides, thereby reducing migraine pain and associated autonomic symptoms.

Side Effects

Common Side Effects

  • Nausea: mild to moderate stomach upset.
  • Dizziness: transient light‑headedness.
  • Tingling sensations: paresthesia in extremities.
  • Chest discomfort: pressure or tightness in the chest.

Serious or Rare Side Effects

  • Coronary vasospasm: chest pain due to reduced coronary blood flow.
  • Severe hypertension: sudden increase in blood pressure.
  • Serotonin syndrome: agitation, hyperthermia, muscle rigidity when combined with other serotonergic agents.
  • Allergic reaction: rash, swelling, or difficulty breathing.

Precautions & Warnings

Before using Imigran Radis, consider the following precautions:

  • Cardiovascular disease: avoid if you have ischemic heart disease, uncontrolled hypertension, or cerebrovascular disorders.
  • Hemiplegic or basilar migraine: contraindicated due to increased vascular risk.
  • Concomitant serotonergic drugs: monitor for signs of serotonin syndrome.
  • Liver or renal impairment: dose adjustment may be required under medical supervision.
  • Pregnancy and lactation: discuss potential risks with a healthcare professional.
  • Store at room temperature: keep in the original container, protect from moisture and direct sunlight.

Avoid Interactions

Imigran Radis may interact with other medicines as follows:

Major Interactions (Avoid)

  • MAO inhibitors: risk of severe hypertension and serotonin syndrome.
  • Ergot derivatives: additive vasoconstrictive effects.
  • SSRIs, SNRIs, or other triptans: increased chance of serotonin syndrome.

Moderate Interactions (Monitor Closely)

  • Antihypertensive agents: may enhance blood pressure‑lowering effects.
  • CYP3A4 inhibitors (e.g., ketoconazole): may raise sumatriptan plasma levels.
  • Other serotonergic agents (e.g., tramadol): monitor for serotonergic toxicity.

Frequently Asked Questions

Imigran Radis contains sumatriptan, which is prescribed for the acute treatment of migraine attacks. It helps relieve headache pain, nausea, and sensitivity to light or sound when taken at the first sign of a migraine.

Sumatriptan works by selectively stimulating serotonin 5‑HT1B and 5‑HT1D receptors. This causes constriction of dilated cranial blood vessels and blocks the release of pain‑triggering neuropeptides, thereby reducing migraine pain and associated symptoms.

The appropriate dose of Imigran Radis is determined by a qualified prescriber based on individual patient factors. Patients should follow the dosing instructions provided by their healthcare professional and not self‑adjust the dose.

Safety of sumatriptan during pregnancy or lactation has not been definitively established. Women who are pregnant, planning to become pregnant, or breastfeeding should discuss potential risks and benefits with their physician before using Imigran Radis.

To place an order, submit an enquiry on the Imigran Radis product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details, and any necessary import documentation.

Imigran Radis (sumatriptan) belongs to the triptan class, which is generally more effective for moderate to severe migraine attacks than simple analgesics. Compared with newer CGRP antagonists, triptans act via serotonin receptors and have a well‑established efficacy profile, though they carry specific vascular contraindications.

Imigran Radis should be stored at room temperature, below 25 °C, in its original packaging. Keep the product away from moisture, direct sunlight, and excessive heat to maintain its stability and potency.

Imigran Radis is taken orally, usually as a tablet. The tablet should be swallowed whole with water, preferably at the first sign of a migraine. Patients should not crush, chew, or dissolve the tablet unless specifically instructed by a healthcare professional.

Serious risks include coronary vasospasm, severe hypertension, and serotonin syndrome, especially when combined with other serotonergic drugs. Patients should seek immediate medical attention if they experience chest pain, a sudden rise in blood pressure, or symptoms such as agitation, fever, or muscle rigidity.

Imigran Radis is contraindicated in individuals with a history of ischemic heart disease, uncontrolled hypertension, cerebrovascular disorders, hemiplegic or basilar migraine, and those taking MAO inhibitors within the past two weeks. It should also be avoided in patients with known hypersensitivity to sumatriptan.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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