Product image of Imigran (Sumatriptan) supplied by GNH India

Imigran

Active Ingredient:
Sumatriptan
Origin:
EU

Imigran (Sumatriptan)

Sumatriptan, the active ingredient in Imigran, is a Triptan (5‑HT1B/1D receptor agonist) presented as a nasal spray for intranasal use. It is indicated for the acute treatment of migraine attacks in adult patients, providing rapid relief of headache and associated symptoms such as nausea, photophobia, and phonophobia.

GNH India supplies Imigran as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide, ensuring consistent quality and regulatory compliance across EU and global markets.

Manufacturer / TM Owner

Glaxosmithkline B.V.

1
Pack/s
This product is added to your enquiry list

Request a Quote

Please fill out the form below and our team will get back to you shortly with pricing and further information.

A minimum order value applies. Our team will confirm the exact amount or quantity after reviewing your requirements.

Indications & Clinical Uses

  • Imigran (sumatriptan) is a Triptan used in the migraine pathway to abort acute attacks.
  • Migraine: provides acute relief of headache and associated symptoms such as nausea, photophobia, and phonophobia.

How It Works

  • Sumatriptan selectively binds to serotonin 5‑HT1B and 5‑HT1D receptors on intracranial blood vessels and trigeminal nerve endings. Activation of these receptors causes cranial vasoconstriction and inhibits the release of vasoactive neuropeptides, thereby interrupting the neurovascular cascade that underlies migraine pain.

Side Effects

Common Side Effects

  • Taste disturbance: altered or unpleasant taste after administration.
  • Nasal irritation: burning, stinging, or discomfort in the nasal passages.
  • Dizziness: sensation of light‑headedness or unsteadiness.
  • Somnolence: mild sleepiness or fatigue.
  • Nausea: feeling of queasiness or upset stomach.
  • Throat irritation: soreness or scratchy feeling in the throat.

Serious or Rare Side Effects

  • Coronary vasospasm: chest pain or signs of reduced heart blood flow.
  • Hypertension: sudden increase in blood pressure.
  • Serotonin syndrome: agitation, hyperthermia, tremor, and confusion when combined with other serotonergic agents.
  • Severe allergic reaction: rash, swelling, or difficulty breathing.
  • Cardiac arrhythmia: irregular heart rhythm.
  • Ischemic stroke: rare occurrence of cerebrovascular events.

Precautions & Warnings

Before using Imigran, consider the following precautions:

  • Cardiovascular disease: avoid in patients with history of coronary artery disease, myocardial infarction, or uncontrolled angina.
  • Hypertension: monitor blood pressure and use only if hypertension is well controlled.
  • Serotonergic agents: assess risk of serotonin syndrome when combined with SSRIs, SNRIs, or MAO inhibitors.
  • Pregnancy: safety not established; prescribe only if potential benefit justifies potential risk to the fetus.
  • Pediatric use: not established in children; use only under specialist supervision.
  • Store at room temperature: keep in original packaging, protect from moisture and direct heat.

Avoid Interactions

Imigran may interact with several medicines. Review the following categories:

Major Interactions (Avoid)

  • MAO inhibitors: concurrent use can precipitate severe hypertension.
  • Other triptans or ergot derivatives: increased risk of vasospastic events.
  • SSRIs, SNRIs, or other serotonergic drugs: heightened risk of serotonin syndrome.

Moderate Interactions (Monitor Closely)

  • Antihypertensive agents: may enhance blood pressure‑lowering effects.
  • CYP3A4 inhibitors (e.g., ketoconazole, erythromycin): may increase sumatriptan plasma levels.
  • Dihydropyridine calcium‑channel blockers: potential additive cardiovascular effects.
  • Oral contraceptives: monitor for increased migraine frequency.
  • NSAIDs: combined use may increase risk of gastrointestinal irritation.

Frequently Asked Questions

Imigran is a prescription nasal spray containing sumatriptan, indicated for the acute treatment of migraine attacks in adults. It is designed to provide rapid relief of headache pain and associated symptoms such as nausea, light sensitivity, and sound sensitivity when taken at the onset of a migraine.

Sumatriptan works by selectively stimulating serotonin 5‑HT1B and 5‑HT1D receptors on cranial blood vessels and trigeminal nerve endings. This action leads to constriction of dilated intracranial vessels and inhibition of neuropeptide release, interrupting the cascade that generates migraine pain.

The dose of Imigran is determined by a qualified prescriber based on the individual patient's needs and clinical response. The prescribing information provides guidance on the number of sprays per dose and the maximum number of doses allowed within a 24‑hour period.

Safety of sumatriptan in pregnancy and lactation has not been definitively established. It should be used only if the potential benefit to the mother outweighs any possible risk to the fetus or infant, and this decision should be made in consultation with a healthcare professional.

To order Imigran, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India supplies hospitals, pharmacies and procurement teams worldwide, and will request verification of trade or institutional credentials before providing pricing, availability, shipping details and any necessary import documentation.

Imigran delivers sumatriptan via the intranasal route, offering faster absorption than oral tablets and an alternative for patients who cannot swallow pills or experience gastrointestinal upset. Compared with other triptans, it provides comparable efficacy but may have a different side‑effect profile, particularly nasal irritation.

Imigran should be stored at room temperature, below 25 °C, in its original container. Protect the spray from moisture and direct sunlight. Do not freeze the product, and keep it out of reach of children.

Imigran is administered as a nasal spray. The patient should gently blow the nose, insert the nozzle into one nostril, and press the pump to deliver the prescribed number of sprays. The dose may be repeated in the other nostril if required, following the prescriber's instructions.

Serious risks include cardiovascular events such as coronary vasospasm, myocardial infarction, and stroke, especially in patients with underlying heart disease. Additionally, serotonin syndrome can occur when combined with other serotonergic drugs. Patients should seek immediate medical attention for chest pain, severe hypertension, or signs of an allergic reaction.

Imigran is contraindicated in patients with a history of coronary artery disease, uncontrolled hypertension, peripheral vascular disease, or severe hepatic impairment. It should also be avoided in individuals who have experienced an allergic reaction to sumatriptan or any component of the nasal spray formulation.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

Disclaimer

At GNH India, we aim to provide information that is expert-reviewed, accurate, and reliable. However, all content on this platform is intended for general informational purposes only and does not constitute professional medical advice, diagnosis, or treatment. While efforts are made to maintain accuracy and currency, the information may contain errors, omissions, or may not reflect the latest developments. Always consult a qualified healthcare professional regarding any medical concerns.

All product names, brand names, trademarks and registered trademarks displayed on this website are the property of their respective owners. This website and its operator are not affiliated with, endorsed by, or authorized by any such trade mark owners unless expressly stated. Any reference to product names or trademarks is made solely for descriptive and informational purposes. No commercial relationship, sponsorship, approval, or association with any trademark owner should be inferred. Information provided herein does not constitute promotion, advertising, or an offer for sale of any medicinal product and is intended solely for general informational purposes.

All trademarks and brand names displayed on this website are used strictly in accordance with the provisions of the Trade Marks Act, 1999, specifically Sections 30 and 30(1) governing fair use. Trademark ownership has been accurately attributed under the "Manufacturer/ TM Owner" section in compliance with statutory requirements.

Related Products

Other formulations containing Sumatriptan

A

A
A

A
A

A
A

A

Browse all products →

Ordering Process

Simple, Secure, and Seamless

Learn how our streamlined ordering process guarantees fast, compliant, and reliable access to essential medicines worldwide.

Quote request form

01

Submit Quote Request Form

Tell us what medications you need by filling out our simple form and uploading a valid document.

Price estimate review

02

We Review & Send Estimate

Our licensed pharmacists will verify your details and provide you with a detailed cost estimate.

Secure payment

03

Confirm & Make Payment

Discuss any queries, approve the estimate, and complete your payment.

Worldwide delivery

04

Get Delivered

Your medicines, safely packed and delivered to your door or nearest airport — hassle-free.

Regulatory recognitions

Quality You Can Trust

Our internationally recognized certifications underscore our commitment to safety, quality, and excellence.

SGS GSDP Certification

GSDP Compliant from SGS

URS ISO 9001

URS ISO 9001 Certification

FDA Maharashtra

Licensed by FDA Maharashtra

IEC License DGFT

IEC License issued by DGFT