Product image of Imigran (Sumatriptan Succinate) supplied by GNH India

Imigran

Active Ingredient:
Sumatriptan Succinate
Origin:
EU

Imigran (Sumatriptan Succinate)

Sumatriptan succinate, the active ingredient in Imigran, is a Triptan (5‑HT1B/1D receptor agonist) presented as an oral tablet for oral use. It is indicated for the acute treatment of migraine attacks, with or without aura, in adult patients. It works by causing cranial blood‑vessel constriction and inhibiting the release of pro‑pain neuropeptides, providing rapid relief of headache and associated symptoms.

GNH India supplies Imigran as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide. The company adheres to stringent quality standards and provides regulatory‑compliant documentation for each batch.

Manufacturer / TM Owner

Glaxosmithkline Single Member A.E.B.E.

1
Pack/s
This product is added to your enquiry list

Request a Quote

Please fill out the form below and our team will get back to you shortly with pricing and further information.

A minimum order value applies. Our team will confirm the exact amount or quantity after reviewing your requirements.

Indications & Clinical Uses

Imigran (sumatriptan) acts on the serotonergic pathway to treat migraine and related headache disorders.

  • Migraine with aura: rapid relief of headache, nausea, photophobia and phonophobia.
  • Migraine without aura: reduction of headache intensity and associated symptoms.
  • Acute cluster headache: alleviation of severe unilateral head pain during an attack.

How It Works

  • Sumatriptan succinate binds selectively to serotonin 5‑HT1B and 5‑HT1D receptors on intracranial blood vessels and trigeminal nerve endings. Activation of 5‑HT1B receptors produces vasoconstriction of dilated cranial arteries, while 5‑HT1D stimulation inhibits release of calcitonin gene‑related peptide and other pro‑inflammatory neuropeptides, thereby interrupting the migraine pain cascade. The combined vascular and neuronal effects lead to a swift decrease in headache severity and associated autonomic symptoms.

Side Effects

Sumatriptan may cause a range of adverse reactions, which are categorized by frequency and severity.

Common Side Effects

  • Chest tightness or pressure: a transient sensation of heaviness in the chest that usually resolves quickly.
  • Tingling or numbness in the face or extremities: mild paresthesia affecting lips, tongue, fingers or toes.
  • Nausea or abdominal discomfort: mild gastrointestinal upset that may accompany the headache relief.

Serious or Rare Side Effects

  • Coronary artery spasm or myocardial infarction: severe cardiac events that require immediate medical attention.
  • Serotonin syndrome when combined with other serotonergic drugs: potentially life‑threatening condition marked by agitation, hyperthermia, and neuromuscular abnormalities.
  • Severe allergic reaction (anaphylaxis): rapid onset of hives, swelling, breathing difficulty, and shock.

Precautions & Warnings

Before prescribing Imigran, clinicians should evaluate the following precautionary considerations.

  • Cardiovascular disease: avoid use in patients with coronary artery disease, angina or recent myocardial infarction.
  • Uncontrolled hypertension: contraindicated in individuals with systolic BP >160 mmHg or diastolic >100 mmHg.
  • History of stroke or transient ischemic attack: not recommended due to risk of cerebral vasoconstriction.
  • Concomitant serotonergic agents: caution when combined with SSRIs, SNRIs, MAO inhibitors or other triptans.
  • Pregnancy and lactation: use only if potential benefit justifies potential risk; data are limited.
  • Store at ambient temperature: keep tablets in original packaging, protect from moisture and direct sunlight.

Avoid Interactions

Sumatriptan may interact with other medicines, and certain combinations should be avoided or closely monitored.

Major Interactions (Avoid)

  • MAO inhibitors: risk of severe serotonin syndrome when used together.
  • SSRIs, SNRIs, or other serotonergic drugs: increased chance of serotonin syndrome.
  • Ergot alkaloids: additive vasoconstrictive effects may precipitate ischemia.

Moderate Interactions (Monitor Closely)

  • CYP3A4 inhibitors (e.g., ketoconazole, erythromycin): may raise sumatriptan plasma levels.
  • CYP3A4 inducers (e.g., rifampin, carbamazepine): may reduce therapeutic effect.
  • Beta‑blockers: can increase sumatriptan exposure and prolong its action.

Frequently Asked Questions

Imigran contains sumatriptan succinate and is prescribed for the acute treatment of migraine attacks, with or without aura, in adult patients. It helps relieve headache pain and associated symptoms such as nausea, sensitivity to light, and sound.

Sumatriptan works by selectively activating serotonin 5‑HT1B and 5‑HT1D receptors. This causes constriction of dilated cranial blood vessels and blocks the release of pain‑triggering neuropeptides from trigeminal nerves, interrupting the migraine cascade.

The appropriate dose of Imigran is determined by a qualified prescriber based on the individual patient's condition, response, and medical history. Dosage may vary, and patients should follow the specific instructions provided by their healthcare professional.

Safety data for sumatriptan in pregnancy and lactation are limited. It should only be used if the potential benefit outweighs any possible risk to the fetus or infant, and the decision must be made by a healthcare provider.

To order Imigran, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India supplies hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Imigran belongs to the triptan class, which provides rapid, targeted relief of migraine by acting on serotonin receptors. Compared with non‑specific analgesics, triptans are generally more effective for moderate to severe migraine and have a distinct mechanism that does not rely on anti‑inflammatory action.

Imigran tablets should be stored at ambient temperature, below 25 °C, in the original container to protect them from moisture and light. Keep the medication out of reach of children and do not use it after the expiry date printed on the package.

Imigran is taken orally as a tablet. The patient swallows the tablet whole with water, typically at the onset of a migraine attack. The exact timing and any repeat dosing should follow the prescriber's instructions.

Serious risks include coronary artery spasm or myocardial infarction, especially in patients with underlying heart disease, and serotonin syndrome when combined with other serotonergic drugs. Immediate medical attention is required if symptoms such as chest pain, severe hypertension, or rapid mental status changes occur.

Imigran is contraindicated in patients with known coronary artery disease, uncontrolled hypertension, a history of stroke or transient ischemic attack, and those taking MAO inhibitors, ergot derivatives, or other triptans. It should also be avoided in individuals with severe hepatic impairment.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

Disclaimer

At GNH India, we aim to provide information that is expert-reviewed, accurate, and reliable. However, all content on this platform is intended for general informational purposes only and does not constitute professional medical advice, diagnosis, or treatment. While efforts are made to maintain accuracy and currency, the information may contain errors, omissions, or may not reflect the latest developments. Always consult a qualified healthcare professional regarding any medical concerns.

All product names, brand names, trademarks and registered trademarks displayed on this website are the property of their respective owners. This website and its operator are not affiliated with, endorsed by, or authorized by any such trade mark owners unless expressly stated. Any reference to product names or trademarks is made solely for descriptive and informational purposes. No commercial relationship, sponsorship, approval, or association with any trademark owner should be inferred. Information provided herein does not constitute promotion, advertising, or an offer for sale of any medicinal product and is intended solely for general informational purposes.

All trademarks and brand names displayed on this website are used strictly in accordance with the provisions of the Trade Marks Act, 1999, specifically Sections 30 and 30(1) governing fair use. Trademark ownership has been accurately attributed under the "Manufacturer/ TM Owner" section in compliance with statutory requirements.

Related Products

Other formulations containing Sumatriptan Succinate

A

A
A

A
A

A
A

A

Browse all products →

Ordering Process

Simple, Secure, and Seamless

Learn how our streamlined ordering process guarantees fast, compliant, and reliable access to essential medicines worldwide.

Quote request form

01

Submit Quote Request Form

Tell us what medications you need by filling out our simple form and uploading a valid document.

Price estimate review

02

We Review & Send Estimate

Our licensed pharmacists will verify your details and provide you with a detailed cost estimate.

Secure payment

03

Confirm & Make Payment

Discuss any queries, approve the estimate, and complete your payment.

Worldwide delivery

04

Get Delivered

Your medicines, safely packed and delivered to your door or nearest airport — hassle-free.

Regulatory recognitions

Quality You Can Trust

Our internationally recognized certifications underscore our commitment to safety, quality, and excellence.

SGS GSDP Certification

GSDP Compliant from SGS

URS ISO 9001

URS ISO 9001 Certification

FDA Maharashtra

Licensed by FDA Maharashtra

IEC License DGFT

IEC License issued by DGFT