Product image of Imigran (Sumatriptan Succinate) supplied by GNH India

Imigran

Active Ingredient:
Sumatriptan Succinate
Origin:
EU

Imigran (Sumatriptan Succinate)

Sumatriptan succinate, the active ingredient in Imigran, is a Triptan presented as an injection for subcutaneous use. It treats acute migraine attacks with or without aura in adult patients.

GNH India supplies Imigran as a licensed, GDP-compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Glaxosmithkline Trading Services Limited

1
Pack/s
This product is added to your enquiry list

Request a Quote

Please fill out the form below and our team will get back to you shortly with pricing and further information.

A minimum order value applies. Our team will confirm the exact amount or quantity after reviewing your requirements.

Indications & Clinical Uses

Imigran is a Triptan indicated for the acute management of migraine and related headache disorders.

  • Migraine attack: provides rapid relief of headache pain, nausea, and photophobia.
  • Migraine with aura: alleviates headache and associated aura symptoms.
  • Acute episodic migraine: reduces the need for additional rescue medication.

How It Works

  • Sumatriptan succinate acts as a selective agonist at serotonin 5‑HT1B and 5‑HT1D receptors located on intracranial blood vessels and trigeminal nerve endings. Activation induces cranial vasoconstriction and blocks the release of pro‑inflammatory neuropeptides, thereby interrupting the pain signaling cascade responsible for migraine attacks.

Side Effects

Common Side Effects

  • Injection site pain: mild to moderate discomfort at the injection site.
  • Tingling or paresthesia: transient sensations in the face or extremities.
  • Flushing: temporary warmth or redness of the skin.
  • Nausea: occasional upset stomach.
  • Dizziness: brief light‑headedness.
  • Chest pressure: mild, non‑cardiac sensation.

Serious or Rare Side Effects

  • Coronary vasospasm: constriction of coronary arteries that may cause chest pain.
  • Myocardial infarction: rare heart attack events.
  • Serotonin syndrome: potentially life‑threatening condition when combined with other serotonergic agents.
  • Severe hypertension: sudden increase in blood pressure.
  • Anaphylaxis: severe allergic reaction requiring immediate medical attention.
  • Severe allergic reaction: including rash, swelling, or difficulty breathing.

Precautions & Warnings

Before using Imigran, consider the following precautions:

  • Cardiovascular assessment: avoid use in patients with known coronary artery disease or uncontrolled hypertension.
  • Serotonergic medications: assess risk of serotonin syndrome when combined with SSRIs, SNRIs, or MAO inhibitors.
  • Pregnancy and lactation: use only if the potential benefit justifies the potential risk; data are limited.
  • Age considerations: safety not established in pediatric patients; generally prescribed for adults.
  • Store at room temperature: keep in the original container, protect from moisture and light.

Avoid Interactions

Imigran may interact with several drug classes.

Major Interactions (Avoid)

  • MAO inhibitors: concurrent use may precipitate serotonin syndrome.
  • Ergot alkaloids: combined use can cause severe vasospasm.
  • Other triptans: additive vasoconstrictive effect; avoid coadministration.

Moderate Interactions (Monitor Closely)

  • SSRIs/SNRIs: increased risk of serotonin syndrome; monitor symptoms.
  • Antihypertensives: may enhance blood‑pressure‑lowering effect.
  • CYP3A4 inhibitors: may increase sumatriptan plasma levels; adjust therapy if needed.

Frequently Asked Questions

Imigran is prescribed for the acute treatment of migraine attacks, with or without aura, in adult patients. It is intended to relieve headache pain and associated symptoms such as nausea, photophobia, and phonophobia when a migraine episode begins.

Sumatriptan, the active ingredient in Imigran, selectively stimulates serotonin 5‑HT1B and 5‑HT1D receptors on cranial blood vessels and trigeminal nerve fibers. This action causes vasoconstriction of dilated intracranial vessels and blocks the release of pain‑triggering neuropeptides, thereby interrupting migraine pain pathways.

The dose of Imigran is determined by the prescribing clinician based on individual patient needs, clinical guidelines, and the severity of the migraine attack. Healthcare professionals select the appropriate amount and frequency in accordance with approved prescribing information.

Safety data for Imigran in pregnancy and lactation are limited. It should only be used when the potential benefit to the mother outweighs any possible risk to the fetus or infant, and the decision should be made in consultation with a qualified healthcare provider.

To order Imigran, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including cold‑chain handling if required), and necessary import documentation.

Imigran belongs to the triptan class, which provides rapid, targeted relief for migraine attacks by acting on serotonin receptors. Compared with non‑specific analgesics, triptans like Imigran address the underlying vascular and neurogenic mechanisms of migraine, often achieving faster and more complete symptom resolution.

Imigran should be stored at room temperature, preferably below 25 °C, in its original packaging. Protect the product from moisture and direct sunlight. Do not freeze the injection solution, and keep it out of reach of children.

Imigran is administered as a subcutaneous injection, typically into the outer thigh or abdomen. The injection is performed by a qualified healthcare professional or by the patient after proper training, using a sterile, single‑use device provided with the product.

Serious risks include coronary vasospasm, myocardial infarction, serotonin syndrome (especially when combined with other serotonergic drugs), severe hypertension, and anaphylactic reactions. Patients should seek immediate medical attention if they experience chest pain, severe shortness of breath, or signs of an allergic reaction.

Imigran is contraindicated in individuals with known coronary artery disease, uncontrolled hypertension, a history of myocardial infarction, severe peripheral vascular disease, or those who have previously experienced an allergic reaction to sumatriptan or any component of the formulation. It is also not recommended for children and adolescents under 18 years of age.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

Disclaimer

At GNH India, we aim to provide information that is expert-reviewed, accurate, and reliable. However, all content on this platform is intended for general informational purposes only and does not constitute professional medical advice, diagnosis, or treatment. While efforts are made to maintain accuracy and currency, the information may contain errors, omissions, or may not reflect the latest developments. Always consult a qualified healthcare professional regarding any medical concerns.

All product names, brand names, trademarks and registered trademarks displayed on this website are the property of their respective owners. This website and its operator are not affiliated with, endorsed by, or authorized by any such trade mark owners unless expressly stated. Any reference to product names or trademarks is made solely for descriptive and informational purposes. No commercial relationship, sponsorship, approval, or association with any trademark owner should be inferred. Information provided herein does not constitute promotion, advertising, or an offer for sale of any medicinal product and is intended solely for general informational purposes.

All trademarks and brand names displayed on this website are used strictly in accordance with the provisions of the Trade Marks Act, 1999, specifically Sections 30 and 30(1) governing fair use. Trademark ownership has been accurately attributed under the "Manufacturer/ TM Owner" section in compliance with statutory requirements.

Ordering Process

Simple, Secure, and Seamless

Learn how our streamlined ordering process guarantees fast, compliant, and reliable access to essential medicines worldwide.

Quote request form

01

Submit Quote Request Form

Tell us what medications you need by filling out our simple form and uploading a valid document.

Price estimate review

02

We Review & Send Estimate

Our licensed pharmacists will verify your details and provide you with a detailed cost estimate.

Secure payment

03

Confirm & Make Payment

Discuss any queries, approve the estimate, and complete your payment.

Worldwide delivery

04

Get Delivered

Your medicines, safely packed and delivered to your door or nearest airport — hassle-free.

Quality You Can Trust

Our internationally recognized certifications underscore our commitment to safety, quality, and excellence.