Product image of Imigran-T (Sumatriptan Succinate) supplied by GNH India

Imigran-T

Active Ingredient:
Sumatriptan Succinate
Origin:
EU

Imigran-T (Sumatriptan Succinate)

Sumatriptan succinate, the active ingredient in Imigran‑T, is a Triptan presented as an oral dosage form for oral use. It is indicated for the acute treatment of migraine attacks in adults and provides rapid relief of headache and associated symptoms.

GNH India supplies Imigran‑T as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Glaxosmithkline Gmbh & Co. Kg

1
Pack/s
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Indications & Clinical Uses

Imigran‑T belongs to the triptan class and is used to treat migraine-related conditions.

  • Migraine without aura: rapid relief of headache, nausea, and photophobia during an acute attack.
  • Migraine with aura: reduction of headache severity after the aura phase when taken early.
  • Acute episodic migraine: termination of an attack when administered at the first sign of pain.

How It Works

  • Sumatriptan succinate acts as a selective agonist at serotonin 5‑HT1B and 5‑HT1D receptors located on cranial blood vessels and trigeminal nerve terminals. Activation of these receptors induces vasoconstriction of intracranial arteries and inhibits the release of pro‑inflammatory neuropeptides, thereby interrupting the migraine pain pathway and providing symptom relief.

Side Effects

Common Side Effects

  • Chest discomfort or tightness
  • Tingling or numbness in fingers or face
  • Nausea or abdominal upset
  • Dizziness or light‑headedness
  • Fatigue or drowsiness
  • Dry mouth

Serious or Rare Side Effects

  • Coronary vasospasm leading to chest pain
  • Serotonin syndrome when combined with serotonergic agents
  • Severe allergic reaction (anaphylaxis)
  • Sudden increase in blood pressure
  • Cardiac arrhythmias

Precautions & Warnings

Imigran‑T should be used with caution in patients with certain medical conditions and in specific situations.

  • Cardiovascular assessment: avoid in patients with known coronary artery disease, uncontrolled hypertension, or history of stroke.
  • Serotonergic agents: do not combine with other serotonergic drugs due to risk of serotonin syndrome.
  • Pregnancy: use only if the potential benefit justifies the potential risk to the fetus.
  • Age: exercise caution in elderly patients because of increased cardiovascular susceptibility.
  • Drug interactions: review all concomitant medications before initiating therapy.
  • Store at ambient temperature: keep below 25°C in the original packaging, protect from moisture.

Avoid Interactions

Sumatriptan may interact with several drug classes that affect serotonergic pathways or cardiovascular function.

Major Interactions (Avoid)

  • SSRIs/SNRIs: increased risk of serotonin syndrome.
  • Ergotamine derivatives: additive vasospastic effects.
  • MAO inhibitors: heightened serotonergic activity.

Moderate Interactions (Monitor Closely)

  • Beta‑blockers: may enhance hypotensive response.
  • CYP3A4 inhibitors: can raise sumatriptan plasma concentrations.

Frequently Asked Questions

Imigran‑T contains sumatriptan succinate and is prescribed for the acute treatment of migraine attacks in adults, helping to relieve headache, nausea, and sensitivity to light or sound when taken at the onset of an episode.

Sumatriptan selectively stimulates serotonin 5‑HT1B and 5‑HT1D receptors on cranial blood vessels and trigeminal nerves, causing vasoconstriction and blocking the release of inflammatory neuropeptides, which together interrupt the migraine pain cascade.

The appropriate dose of Imigran‑T is determined by the prescribing healthcare professional based on the patient’s clinical condition, age, and response to therapy. Patients should follow the prescriber’s instructions and not adjust the dose on their own.

The safety of sumatriptan in pregnancy and lactation has not been definitively established. It should only be used if the potential benefit outweighs any possible risk to the fetus or infant, and the decision must be made by a qualified healthcare provider.

To place an order, submit an enquiry on the Imigran‑T product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details, and any necessary import documentation.

Imigran‑T belongs to the triptan class, which is generally more effective for moderate to severe migraine attacks than simple analgesics. Compared with newer CGRP antagonists, triptans act via serotonin receptors and have a well‑established efficacy profile, though they carry specific cardiovascular considerations.

Imigran‑T should be stored at room temperature, below 25 °C, in its original packaging to protect it from moisture and light. Keep the product out of reach of children and do not use it after the expiration date.

Imigran‑T is taken orally with a glass of water. It is usually administered at the first sign of a migraine attack and may be repeated after two hours if needed, but no more than the maximum daily dose prescribed by the healthcare professional.

Serious risks include coronary vasospasm, which can cause chest pain, and serotonin syndrome when combined with other serotonergic drugs. Patients should seek immediate medical attention if they experience severe chest discomfort, rapid heart rate, or signs of an allergic reaction.

Imigran‑T is contraindicated in patients with a history of coronary artery disease, uncontrolled hypertension, severe hepatic impairment, or known hypersensitivity to sumatriptan or any excipients. It should also be avoided in individuals taking other triptans or ergotamine-containing medications.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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