Product image of Imolast (Timolol Maleate, Latanoprost) supplied by GNH India

Imolast

Active Ingredient:
Timolol Maleate, Latanoprost
Origin:
EU

Imolast (Timolol Maleate, Latanoprost)

Timolol maleate and Latanoprost, the active ingredients in Imolast, are a beta‑blocker and prostaglandin analog presented as eye drops for ocular use. They lower intra‑ocular pressure in patients with open‑angle glaucoma or ocular hypertension.
GNH India supplies Imolast as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Genetic Spa

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Indications & Clinical Uses

Imolast is indicated for conditions affecting ocular fluid dynamics and intra‑ocular pressure.

  • Open‑angle glaucoma: reduces intra‑ocular pressure to slow optic nerve damage.
  • Ocular hypertension: lowers pressure to prevent progression to glaucoma.
  • Pseudoexfoliative glaucoma: helps control pressure in this secondary open‑angle form.

How It Works

  • Timolol maleate non‑selectively blocks β‑adrenergic receptors in the ciliary body, decreasing aqueous humor production. Latanoprost, a prostaglandin F2α analog, binds FP receptors to remodel the extracellular matrix, enhancing uveoscleral outflow of aqueous humor. The combined actions result in a net reduction of intra‑ocular pressure.

Side Effects

Imolast may cause ocular and systemic reactions.

Common Side Effects

  • Blurred vision: transient visual disturbance after instillation.
  • Eye irritation: burning or stinging sensation.
  • Conjunctival hyperemia: mild redness of the eye.
  • Itching or foreign‑body sensation.
  • Increased eyelash growth.
  • Mild eyelid pigmentation changes.

Serious or Rare Side Effects

  • Significant ocular inflammation or uveitis.
  • Severe allergic reaction: swelling, rash, or difficulty breathing.
  • Permanent iris color change.
  • Worsening of glaucoma despite therapy.
  • Systemic β‑blocker effects: bradycardia, hypotension, bronchospasm.
  • Corneal edema or persistent visual loss.

Precautions & Warnings

Before prescribing Imolast, clinicians should consider several safety aspects.

  • Monitor intra‑ocular pressure: schedule regular pressure checks.
  • Assess for β‑blocker contraindications: asthma, COPD, severe bradycardia.
  • Avoid concurrent ocular medications: separate dosing times to prevent interactions.
  • Use caution in pregnancy: limited safety data, weigh benefits against risks.
  • Remove contact lenses before instillation: lenses may retain drug and cause irritation.
  • Store at room temperature: keep bottle tightly closed, protect from light and moisture.

Avoid Interactions

Imolast can interact with other systemic and ocular agents.

Major Interactions (Avoid)

  • Systemic β‑blockers: additive bradycardia or hypotension.
  • Other prostaglandin analog eye drops: increased risk of ocular side effects.
  • Monoamine oxidase inhibitors (MAOIs): potential systemic cardiovascular effects.

Moderate Interactions (Monitor Closely)

  • Topical anesthetic drops: may heighten corneal toxicity.
  • Anticholinergic eye drops: could alter pupil response and affect pressure control.

Frequently Asked Questions

Imolast is a combination eye‑drop formulation indicated for the treatment of open‑angle glaucoma and ocular hypertension. By lowering intra‑ocular pressure, it helps protect the optic nerve from damage and reduces the risk of vision loss associated with these conditions.

Timolol maleate is a non‑selective β‑adrenergic antagonist that blocks β‑receptors in the ciliary body. This inhibition reduces the production of aqueous humor, leading to a decrease in intra‑ocular pressure, which is essential in managing glaucoma.

The dosing regimen for Imolast is determined by the prescribing clinician based on individual patient needs. Typically, one drop is instilled in the affected eye(s) once daily, but the exact frequency and duration are set by the healthcare professional.

Safety data for Imolast in pregnancy and lactation are limited. It should only be used if the potential benefit justifies any potential risk to the fetus or infant, and the decision should be made in consultation with a qualified healthcare provider.

To request Imolast, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Imolast combines a beta‑blocker (timolol) and a prostaglandin analog (latanoprost) in a single formulation, offering dual mechanisms of action. Compared with monotherapy agents, this combination can achieve greater intra‑ocular pressure reduction with a single daily drop, potentially improving adherence.

Imolast should be stored at room temperature, below 25 °C. Keep the bottle tightly closed, protect it from direct light and moisture, and do not freeze. Discard any solution that appears discolored or contains particles.

Imolast is applied as an eye drop. The patient should wash hands, tilt the head back, pull down the lower eyelid to create a pocket, and instill one drop into the conjunctival sac. Close the eye gently for a few minutes and avoid touching the tip of the bottle to any surface.

Serious risks include significant ocular inflammation, severe allergic reactions, permanent changes in iris color, worsening of glaucoma despite therapy, and systemic β‑blocker effects such as bradycardia, hypotension, or bronchospasm, especially in patients with respiratory disease.

Imolast is contraindicated in patients with known hypersensitivity to timolol, latanoprost, or any excipients, as well as those with severe asthma, chronic obstructive pulmonary disease, sinus bradycardia, or advanced heart block. Caution is also advised for individuals with active ocular infections.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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