Product image of Imovane (Zopiclone) supplied by GNH India

Imovane

Active Ingredient:
Zopiclone
Origin:
EU

Imovane (Zopiclone)

Zopiclone, the active ingredient in Imovane, is a cyclopyrrolone (non‑benzodiazepine hypnotic) presented as an oral tablet for oral use. It is prescribed for the short‑term treatment of insomnia in adults who have difficulty falling or staying asleep.

GNH India supplies Imovane as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide. The company follows strict quality standards to ensure reliable sourcing for regulated markets. It also provides comprehensive regulatory support and efficient, timely delivery across global regions.

Manufacturer / TM Owner

Sanofi Winthrop Industrie

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Indications & Clinical Uses

  • Zopiclone acts on the central nervous system to promote sleep in patients with insomnia.
  • Insomnia (short‑term): improves sleep onset and maintenance in adults with transient sleep disturbance.
  • Sleep onset insomnia: reduces the time required to fall asleep during the first night of treatment.
  • Sleep maintenance insomnia: decreases nocturnal awakenings and prolongs total sleep time.
  • Elderly patients with insomnia: provides a sleep aid with careful monitoring for falls.
  • Acute stress‑related insomnia: offers temporary relief under medical supervision.

How It Works

  • Zopiclone binds to the benzodiazepine site on GABA‑A receptors as a positive allosteric modulator, enhancing the inhibitory effect of GABA. This increased neuronal inhibition reduces central nervous system activity, facilitating the initiation and maintenance of sleep without directly activating the receptor itself.

Side Effects

Zopiclone may cause a range of adverse reactions, varying from mild to serious.

Common Side Effects

  • Drowsiness: feeling of sleepiness during the day.
  • Dry mouth: reduced salivary flow causing discomfort.
  • Headache: mild to moderate cranial pain.
  • Dizziness: sensation of light‑headedness or unsteadiness.

Serious or Rare Side Effects

  • Complex sleep behaviours: activities such as sleep‑walking or sleep‑driving.
  • Allergic reactions: rash, swelling, or difficulty breathing.
  • Depression or suicidal thoughts: mood changes requiring immediate medical attention.

Precautions & Warnings

Zopiclone should be used with caution and according to medical guidance.

  • Use only as prescribed: limit therapy to short periods to reduce dependence risk.
  • Avoid alcohol: concurrent use may intensify sedation and respiratory depression.
  • Caution in elderly: increased susceptibility to falls and cognitive impairment.
  • Assess renal and hepatic function: dose adjustment may be required in impairment.
  • Do not operate machinery or drive: residual effects can impair alertness.
  • Store at ambient temperature: keep in original packaging, protect from moisture.

Avoid Interactions

Zopiclone can interact with other substances that affect the central nervous system.

Major Interactions (Avoid)

  • Alcohol: additive central nervous system depression.
  • Opioids: heightened risk of respiratory depression.
  • Other sedative hypnotics (e.g., benzodiazepines): excessive sedation.

Moderate Interactions (Monitor Closely)

  • CYP3A4 inhibitors (e.g., ketoconazole, erythromycin): may increase plasma concentrations.
  • CYP3A4 inducers (e.g., rifampicin, carbamazepine): may reduce effectiveness.
  • Antihistamines (e.g., diphenhydramine): may enhance sedative effect.

Frequently Asked Questions

Imovane contains the hypnotic agent Zopiclone and is indicated for the short‑term treatment of insomnia in adults. It helps patients who have difficulty falling asleep, staying asleep, or experience frequent nighttime awakenings, providing a more restorative sleep pattern during a limited treatment period.

Zopiclone binds to the benzodiazepine site on GABA‑A receptors as a positive allosteric modulator. By enhancing the natural inhibitory action of GABA, it reduces neuronal excitability in the brain, which promotes the onset of sleep and helps maintain sleep throughout the night.

The appropriate dose of Imovane is determined by a qualified prescriber based on the individual’s age, health status, and response to therapy. Physicians typically start with the lowest effective dose and adjust as needed, while keeping treatment duration as short as clinically appropriate.

Safety data for Zopiclone in pregnancy and lactation are limited. It is generally advised to avoid use unless the potential benefit outweighs the risk. Women who are pregnant, planning pregnancy, or breastfeeding should discuss alternative sleep‑management strategies with their healthcare provider.

To order Imovane, submit an enquiry on the product page at gnhindia.com specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Imovane (Zopiclone) belongs to the cyclopyrrolone class, whereas many other hypnotics, such as temazepam, are benzodiazepines. Both promote sleep, but Zopiclone has a slightly different receptor binding profile and may be associated with a lower risk of certain withdrawal symptoms, though individual response varies.

Imovane tablets should be stored at ambient temperature, below 25 °C, in their original container to protect them from moisture and light. Keep the medication out of reach of children and avoid storing it in bathrooms or other humid environments.

Imovane is taken orally, usually with a glass of water, just before bedtime. It should be taken only when the patient can allow for a full night’s sleep (7–8 hours) and should not be combined with alcohol or other central nervous system depressants.

Serious risks include complex sleep behaviours such as sleep‑walking or sleep‑driving, severe allergic reactions (rash, swelling, breathing difficulty), and mood changes like depression or suicidal thoughts. If any of these occur, immediate medical attention is required.

Imovane should be avoided in patients with known hypersensitivity to Zopiclone, severe hepatic impairment, a history of substance misuse, or those who are unable to stay in bed for a full night’s sleep. Caution is also advised for individuals with untreated sleep‑apnoea or severe respiratory disorders.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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