Product image of Imovax Polio (Poliovirus (Inactivated) Type 3 (Saukett Strain), Poliovirus (Inactivated) Type 2 (Mef-1 Strain), Po) supplied by GNH India

Imovax Polio

Active Ingredient:
Poliovirus (Inactivated) Type 3 (Saukett Strain), Poliovirus (Inactivated) Type 2 (Mef-1 Strain), Po
Origin:
EU

Imovax Polio (Poliovirus (Inactivated) Type 3 (Saukett Strain), Poliovirus (Inactivated) Type 2 (Mef-1 Strain), Po)

Inactivated poliovirus vaccine, the active ingredient in Imovax Polio, is a vaccine presented as an injectable solution for intramuscular or subcutaneous use. It induces immunity to prevent poliomyelitis caused by poliovirus types 1, 2 and 3 in children and adults, and is used in routine immunization programs.

GNH India supplies Imovax Polio as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide, with distribution aligned to EU regulatory standards and cold‑chain logistics for vaccine integrity, ensuring timely delivery and support.

Manufacturer / TM Owner

Sanofi Winthrop Industrie

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Indications & Clinical Uses

Imovax Polio is an inactivated poliovirus vaccine used to prevent viral infection of the nervous system.

  • Poliomyelitis prevention: Provides active immunity that protects against disease caused by poliovirus types 1, 2 and 3.
  • Travel immunization: Safeguards travelers visiting regions where poliovirus transmission may occur.
  • Outbreak control: Supports public health campaigns to halt poliovirus spread during community outbreaks.

How It Works

  • The vaccine contains chemically inactivated whole poliovirus particles of types 1, 2 and 3. After intramuscular or subcutaneous injection, the viral antigens are taken up by antigen‑presenting cells, stimulating B‑cell production of neutralizing antibodies and priming T‑cell responses. The resulting humoral immunity blocks viral replication in the gut and prevents neuroinvasion, thereby averting paralytic disease and contributes to herd immunity when coverage is high.

Side Effects

Injection of Imovax Polio may be associated with local and systemic reactions.

Common Side Effects

  • Pain at injection site: mild to moderate discomfort where the vaccine is administered.
  • Redness or swelling: localized erythema that typically resolves within a few days.
  • Fever: transient elevation of body temperature, often low grade.
  • Headache or fatigue: general feeling of tiredness or mild headache after vaccination.

Serious or Rare Side Effects

  • Allergic reaction (anaphylaxis): severe hypersensitivity requiring immediate medical attention.
  • Guillain‑Barré syndrome: rare neurological disorder characterized by muscle weakness.
  • Vaccine‑associated paralytic poliomyelitis: extremely rare occurrence of paralysis following vaccination.

Precautions & Warnings

Before administering Imovax Polio, consider the following safety measures.

  • Assess immunocompetence: avoid in severely immunocompromised patients.
  • Screen for allergy: defer if known hypersensitivity to any vaccine component.
  • Delay vaccination: postpone during acute febrile illness.
  • Pregnancy considerations: use only if benefits outweigh risks.
  • Store at 2-8°C: keep refrigerated, protect from light, do not freeze or shake.

Avoid Interactions

Imovax Polio may interact with other medical products; review the following.

Major Interactions (Avoid)

  • Live vaccines: avoid simultaneous administration with live attenuated vaccines.
  • Immunoglobulin therapy: postpone vaccination for at least 4 weeks after receipt.
  • Blood products: defer vaccination for 2 weeks after transfusion.

Moderate Interactions (Monitor Closely)

  • Immunosuppressive drugs: monitor antibody response for adequate protection.
  • Antipyretics: may mask fever post‑vaccination, use with caution.
  • Anticoagulants: monitor injection site for prolonged bleeding.

Frequently Asked Questions

Imovax Polio is an inactivated poliovirus vaccine indicated for the prevention of poliomyelitis caused by poliovirus types 1, 2 and 3. It is used in routine immunization programs for children and adults, as well as for travelers and outbreak control measures.

The vaccine contains chemically inactivated whole poliovirus particles of the three serotypes. After injection, the viral antigens are processed by the immune system, prompting B‑cells to produce neutralizing antibodies and activating T‑cell responses. This immunity blocks viral replication in the gut and prevents spread to the nervous system.

The dosing schedule for Imovax Polio is determined by the prescribing healthcare professional based on age, vaccination history, and regional immunization guidelines. The prescriber will specify the number of doses, intervals, and route of administration appropriate for each patient.

Safety data for Imovax Polio in pregnancy are limited, and the product is classified as pregnancy category unknown. It should be administered only if the potential benefit justifies any potential risk to the fetus. Breastfeeding is not contraindicated, but the decision should be made in consultation with a healthcare provider.

To place an order, submit an enquiry on the Imovax Polio product page at gnhindia.com, specifying the required quantity. GNH India supplies hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, cold‑chain shipping details and any necessary import documentation.

Imovax Polio is an inactivated (killed) poliovirus vaccine, whereas oral polio vaccine (OPV) contains live attenuated virus. Inactivated vaccines cannot cause vaccine‑derived poliovirus infection and are preferred in settings where OPV‑related risks are a concern. Both provide protection against the three poliovirus serotypes, but administration routes and storage requirements differ.

Imovax Polio must be stored at 2‑8 °C in a refrigerator. Keep the vials in the original packaging, protect them from light, and avoid freezing or shaking. Once reconstituted, use the vaccine promptly according to the manufacturer's instructions and discard any unused portion.

The vaccine is supplied as a lyophilized powder that is reconstituted with a sterile diluent. It is then administered by a healthcare professional via intramuscular or subcutaneous injection, typically in the deltoid or anterolateral thigh muscle, following aseptic technique.

Serious but rare risks include severe allergic reactions such as anaphylaxis, Guillain‑Barré syndrome, and vaccine‑associated paralytic poliomyelitis. Immediate medical attention is required if symptoms of a severe reaction occur after vaccination.

Individuals with a known severe allergy to any component of the vaccine, or those who have experienced a previous serious reaction to an inactivated poliovirus vaccine, should not receive Imovax Polio. Additionally, severely immunocompromised patients should be evaluated carefully before vaccination.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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