Product image of Imovax Polio (Poliovirus (Inactivated) Type 3 (Saukett Strain), Poliovirus (Inactivated) Type 2 (Mef-1 Strain), Po) supplied by GNH India

Imovax Polio

Active Ingredient:
Poliovirus (Inactivated) Type 3 (Saukett Strain), Poliovirus (Inactivated) Type 2 (Mef-1 Strain), Po
Origin:
EU

Imovax Polio (Poliovirus (Inactivated) Type 3 (Saukett Strain), Poliovirus (Inactivated) Type 2 (Mef-1 Strain), Po)

Inactivated poliovirus vaccine, the active ingredient in Imovax Polio, is a vaccine presented as an injection for intramuscular and subcutaneous use. It is used to prevent poliomyelitis in infants, children, and adults by inducing immunity against poliovirus types 1, 2, and 3.

GNH India supplies Imovax Polio as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Sanofi Winthrop Industrie

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Indications & Clinical Uses

Imovax Polio is an inactivated poliovirus vaccine that provides active immunization against poliovirus infection.

  • Poliomyelitis prevention: Provides immunity to protect against poliovirus infection and disease.
  • Infant and child immunization: Establishes protective antibody levels after the primary vaccination series.
  • Adult booster vaccination: Reinforces immunity for travelers, outbreak control, or waning protection.

How It Works

  • Imovax Polio contains chemically inactivated whole poliovirus particles of types 1, 2 and 3. After intramuscular or subcutaneous injection, the viral antigens are taken up by antigen‑presenting cells, stimulating B‑cell production of neutralising antibodies and generating memory responses that prevent future poliovirus replication and disease.

Side Effects

Common Side Effects

  • Injection site pain: mild to moderate discomfort at the injection site.
  • Redness or swelling: localized erythema or edema.
  • Fever: transient low‑grade temperature rise.
  • Headache: mild headache within 24 hours.
  • Fatigue: temporary tiredness.
  • Myalgia: muscle aches near the injection area.

Serious or Rare Side Effects

  • Anaphylaxis: severe allergic reaction requiring immediate medical attention.
  • Guillain‑Barré syndrome: rare neurologic disorder with muscle weakness.
  • Seizures: infrequent convulsive episodes.
  • Severe hypotension: marked drop in blood pressure.
  • Persistent high fever: fever lasting more than 48 hours.
  • Vasovagal syncope: fainting episodes post‑injection.

Precautions & Warnings

Imovax Polio should be administered according to national immunisation schedules and under professional supervision.

  • Pregnancy: safety not established; vaccinate only if clearly needed.
  • Breastfeeding: limited data; weigh benefits against potential risks.
  • Immunocompromised patients: generally safe but monitor immune response.
  • Known allergy: avoid if hypersensitivity to any vaccine component.
  • Concurrent live vaccines: may be given but follow recommended intervals.
  • Store at 2-8°C: keep refrigerated, protect from light, do not freeze or shake.

Avoid Interactions

Imovax Polio may interact with other agents that affect immune response.

Major Interactions (Avoid)

  • Immunoglobulin therapy: can reduce vaccine efficacy if given concurrently.
  • Live viral vaccines within 4 weeks: may interfere with immune response.

Moderate Interactions (Monitor Closely)

  • Antipyretics: may mask post‑vaccination fever.
  • Immunosuppressive drugs: may diminish antibody production.
  • Recent blood product transfusion: possible reduced immunogenicity.

Frequently Asked Questions

Imovax Polio is an inactivated poliovirus vaccine indicated for the prevention of poliomyelitis. It induces protective immunity against poliovirus types 1, 2 and 3 in infants, children and adults, and may be used as a primary series or booster dose according to national immunisation schedules.

The vaccine contains chemically inactivated whole poliovirus particles. After injection, the antigens are processed by antigen‑presenting cells, prompting B‑cells to produce neutralising antibodies. These antibodies block future infection by live poliovirus, providing long‑lasting humoral immunity without the risk of viral replication.

The specific dose and schedule of Imovax Polio are determined by the prescribing healthcare professional based on age, immunisation history and local guidelines. The prescriber selects the appropriate volume and timing for the primary series and any required booster doses.

Safety data for Imovax Polio in pregnancy are limited, so it should be administered only if the potential benefit justifies any potential risk. Limited information is available for breastfeeding; the decision should consider the importance of protecting the infant against poliovirus infection.

To order Imovax Polio, submit an enquiry on the product page at gnhindia.com with the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, cold‑chain shipping details and necessary import documentation.

Imovax Polio is an inactivated poliovirus vaccine (IPV) whereas oral polio vaccine (OPV) contains live attenuated virus. IPV does not carry a risk of vaccine‑derived poliovirus and is preferred in settings where OPV‑related outbreaks are a concern. Both provide immunity, but IPV requires injection and multiple doses for optimal protection.

Imovax Polio must be stored refrigerated at 2‑8 °C. It should be kept in the original packaging, protected from light, and must not be frozen or shaken. Maintaining the cold chain during transport and storage preserves vaccine potency.

The vaccine is administered by a trained healthcare professional via intramuscular or subcutaneous injection, typically in the anterolateral thigh for infants or the deltoid muscle for older children and adults. The injection site should be cleaned with an antiseptic before administration.

Serious but rare risks include severe allergic reactions such as anaphylaxis, Guillain‑Barré syndrome, and prolonged high fever. Any signs of a severe reaction, such as difficulty breathing, swelling of the face or throat, or persistent high fever, require immediate medical evaluation.

Individuals with a known severe allergy to any component of the vaccine, including the inactivated virus or stabilisers, should not receive Imovax Polio. Persons with acute moderate or severe illness should defer vaccination until recovery. The vaccine is contraindicated in those with a history of severe vaccine‑related adverse events.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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