Product image of Imovax Polio (Poliovirus (Inactivated) Type 3 (Saukett Strain), Poliovirus (Inactivated) Type 2 (Mef-1 Strain), Po) supplied by GNH India

Imovax Polio

Active Ingredient:
Poliovirus (Inactivated) Type 3 (Saukett Strain), Poliovirus (Inactivated) Type 2 (Mef-1 Strain), Po
Origin:
EU

Imovax Polio (Poliovirus (Inactivated) Type 3 (Saukett Strain), Poliovirus (Inactivated) Type 2 (Mef-1 Strain), Po)

Poliovirus (Inactivated) Type 3 (Saukett Strain), Poliovirus (Inactivated) Type 2 (Mef-1 Strain) and Poliovirus (Inactivated) Type 1 (Mahoney Strain), the active ingredient in Imovax Polio, is an antiviral vaccine presented as an injectable solution for intramuscular or subcutaneous administration. It induces active immunity and is used to prevent poliomyelitis caused by poliovirus types 1, 2 and 3 in children and adults at risk.

GNH India supplies Imovax Polio as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies, clinics and health‑care providers throughout worldwide.

Manufacturer / TM Owner

Sanofi Winthrop Industrie

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Indications & Clinical Uses

Imovax Polio is an inactivated polio vaccine used to prevent poliomyelitis, a viral infection of the nervous system.

  • Poliomyelitis (type 1): Provides immunity against type 1 poliovirus.
  • Poliomyelitis (type 2): Provides immunity against type 2 poliovirus.
  • Poliomyelitis (type 3): Provides immunity against type 3 poliovirus.

How It Works

  • Imovax Polio contains chemically inactivated whole poliovirus particles of types 1, 2 and 3. After intramuscular or subcutaneous injection, the viral antigens are taken up by antigen‑presenting cells, stimulating a humoral immune response that generates neutralizing antibodies against the viral capsid proteins, thereby preventing future infection without replicating in the host.

Side Effects

Common Side Effects

  • Injection site pain, redness or swelling.
  • Low‑grade fever.
  • Headache.
  • Fatigue.
  • Nausea.
  • Muscle aches.

Serious or Rare Side Effects

  • Anaphylactic or severe allergic reactions.
  • Guillain‑Barré syndrome.
  • Seizures.
  • Persistent high fever.
  • Severe hypotension.
  • Neurological complications such as encephalitis.

Precautions & Warnings

Before vaccination, consider the following precautions:

  • Allergy screening: Verify no severe hypersensitivity to vaccine components.
  • Acute illness: Defer administration in persons with moderate or severe fever.
  • Observation: Monitor the patient for at least 15 minutes after injection.
  • Immunocompromised status: Counsel that immune response may be reduced.
  • Pregnancy and lactation: Discuss potential risks with a healthcare professional; safety data are limited.
  • Store at 2‑8 °C: Keep refrigerated, protect from light, do not freeze or shake.

Avoid Interactions

Imovax Polio may interact with other agents as follows:

Major Interactions (Avoid)

  • Live attenuated vaccines administered concurrently: May interfere with immune response.
  • Immunoglobulin therapy given within 4 weeks: Can reduce vaccine efficacy.

Moderate Interactions (Monitor Closely)

  • Immunosuppressive therapy: May diminish antibody production.
  • Chronic corticosteroid use: May lower immunogenicity.
  • Underlying immunodeficiency: May affect vaccine response.
  • Recent blood product transfusion: May alter antibody development.

Frequently Asked Questions

Imovax Polio is an inactivated polio vaccine indicated for the prevention of poliomyelitis caused by poliovirus types 1, 2 and 3. It is administered to individuals who need protection against poliovirus infection, including children and adults in endemic or travel‑risk settings.

The vaccine contains chemically inactivated whole poliovirus particles of the three serotypes. After injection, the viral antigens are processed by the immune system, prompting B‑cell activation and the production of neutralizing antibodies that block future infection without the virus replicating in the body.

The dosing regimen for Imovax Polio is determined by the prescribing healthcare professional based on age, immunization history and local guidelines. The prescriber decides the number of doses, interval between doses and the route of administration.

Safety data for Imovax Polio in pregnancy and lactation are limited. Healthcare providers should evaluate the potential benefits and risks before vaccinating pregnant or breastfeeding individuals, and discuss any concerns with the patient.

To order Imovax Polio, submit an enquiry on the product page at gnhindia.com specifying the required quantity. GNH India supplies hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, cold‑chain shipping details and necessary import documentation.

Imovax Polio is an inactivated polio vaccine (IPV) that does not contain live virus, unlike oral polio vaccine (OPV). IPV carries no risk of vaccine‑derived poliovirus and is preferred in settings where eradication is a priority, while OPV is easier to administer orally but can rarely revert to neurovirulent forms.

Imovax Polio must be stored refrigerated at 2 °C to 8 °C. Keep the vials in the original packaging, protect them from light, and avoid freezing or shaking the solution. Do not use the product if the cold‑chain has been broken.

The vaccine is supplied as an injectable solution and is given by a trained healthcare professional via intramuscular or subcutaneous injection, typically in the deltoid or anterolateral thigh muscle, following aseptic technique.

Serious adverse events, although rare, include severe allergic reactions such as anaphylaxis, Guillain‑Barré syndrome, seizures, persistent high fever, severe hypotension and other neurological complications. Immediate medical attention is required if any of these occur after vaccination.

Individuals with a known severe allergy to any component of the vaccine, those who have experienced a previous serious reaction to an inactivated polio vaccine, and persons with acute moderate or severe illness should defer vaccination until the condition resolves.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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