Product image of Imovax Polio (Poliovirus (Inactivated) Type 3 (Saukett Strain), Poliovirus (Inactivated) Type 2 (Mef-1 Strain), Po) supplied by GNH India

Imovax Polio

Active Ingredient:
Poliovirus (Inactivated) Type 3 (Saukett Strain), Poliovirus (Inactivated) Type 2 (Mef-1 Strain), Po
Origin:
EU

Imovax Polio (Poliovirus (Inactivated) Type 3 (Saukett Strain), Poliovirus (Inactivated) Type 2 (Mef-1 Strain), Po)

Poliovirus (Inactivated) Type 3 (Saukett Strain), Poliovirus (Inactivated) Type 2 (Mef-1 Strain), and Poliovirus (Inactivated) Type 1 (Mahoney Strain), the active ingredient in Imovax Polio, is an inactivated vaccine presented as a sterile suspension for intramuscular or subcutaneous use. It is used to prevent poliomyelitis in individuals at risk.

GNH India supplies Imovax Polio as a licensed, GDP-compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Sanofi Winthrop Industrie

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Indications & Clinical Uses

Imovax Polio is an inactivated poliovirus vaccine indicated for the prevention of poliomyelitis, a viral infection of the nervous system.

  • Poliomyelitis (polio): induces protective immunity that prevents infection and disease.
  • Travel to endemic regions: provides immunity before exposure to circulating poliovirus.
  • Outbreak response: used in mass vaccination campaigns to interrupt transmission.

How It Works

  • Imovax Polio contains whole poliovirus particles that have been chemically inactivated, preserving their antigenic structure. After injection, the immune system recognizes viral capsid proteins, activates B‑cell and T‑cell responses, and produces neutralising antibodies that block future infection by wild‑type poliovirus strains.

Side Effects

Common Side Effects

  • Injection site pain: mild to moderate discomfort at the injection site.
  • Redness or swelling: localized erythema or edema.
  • Low‑grade fever: transient temperature rise within 24‑48 hours.
  • Headache: mild headache following immunisation.
  • Fatigue: temporary tiredness.

Serious or Rare Side Effects

  • Anaphylaxis: severe allergic reaction requiring immediate medical attention.
  • Guillain‑Barré syndrome: rare autoimmune neuropathy.
  • Seizures: infrequent neurologic events.
  • Encephalitis: very rare inflammation of the brain.
  • Severe hypotension: marked drop in blood pressure post‑injection.

Precautions & Warnings

Precautions should be observed when administering Imovax Polio.

  • Allergy assessment: avoid if known hypersensitivity to any vaccine component.
  • Immunocompromised patients: evaluate risk as response may be reduced.
  • Pregnancy: discuss benefits versus potential risks with a healthcare provider.
  • Concurrent vaccines: follow recommended schedules and separate if required.
  • Storage at 2-8°C: keep refrigerated, protect from light, do not freeze or shake.

Avoid Interactions

Vaccination may be influenced by other therapies.

Major Interactions (Avoid)

  • Live viral vaccines: avoid simultaneous administration to prevent interference.
  • Immunoglobulin therapy: may diminish vaccine efficacy.
  • Blood products: can affect immune response.

Moderate Interactions (Monitor Closely)

  • Antipyretics (acetaminophen, ibuprofen): may mask fever, monitor symptom relief.
  • Corticosteroids: may reduce immunogenicity, assess timing and dose.

Frequently Asked Questions

Imovax Polio is an inactivated poliovirus vaccine used to prevent poliomyelitis, a paralytic disease caused by wild poliovirus. It is administered to individuals who need protection before travel to endemic areas, during routine childhood immunisation programmes, or as part of outbreak control measures.

The vaccine contains whole poliovirus particles that have been chemically inactivated, preserving their surface antigens. When injected, these antigens stimulate the immune system to produce neutralising antibodies and cellular immunity, which together block infection by live poliovirus if the person is later exposed.

The dosing schedule for Imovax Polio is determined by the prescribing healthcare professional based on age, immunisation history and local public‑health guidelines. The prescriber selects the appropriate number of doses, intervals and route of administration for each patient.

Safety data for Imovax Polio in pregnancy are limited, so the vaccine should only be given when the potential benefit outweighs any theoretical risk. Breastfeeding is not a contraindication, but mothers should discuss vaccination with their obstetrician or paediatrician to make an informed decision.

To place an order, submit an enquiry on the Imovax Polio product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, cold‑chain shipping details and any necessary import documentation.

Imovax Polio is an inactivated (killed) vaccine, whereas oral polio vaccine (OPV) uses a live attenuated virus. Inactivated vaccines cannot cause vaccine‑derived poliovirus infection and are preferred in settings where OPV‑related risks must be avoided, such as in immunocompromised individuals or high‑income countries.

Imovax Polio must be stored refrigerated at 2 °C to 8 °C. It should be kept in its original packaging, protected from light, and must never be frozen or shaken. Prior to administration, the suspension should be inspected for clarity and particulate matter.

The vaccine is supplied as a sterile suspension for injection. It is administered by a qualified healthcare professional via the intramuscular or subcutaneous route, typically into the deltoid or anterolateral thigh muscle, following the prescribed dosing schedule.

Serious adverse events are rare but include anaphylactic reactions, Guillain‑Barré syndrome, seizures, encephalitis and severe hypotension. Any signs of a severe allergic reaction—such as difficulty breathing, swelling of the face or throat, or a rapid heartbeat—require immediate medical attention.

Individuals with a known severe allergy to any component of the vaccine, including the inactivated virus or stabilisers, should not receive Imovax Polio. Persons with a history of severe anaphylaxis to previous doses of any poliovirus vaccine should also be excluded until evaluated by a specialist.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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