Product image of Imovax (Td) Adult (Diphtheria Toxoid, Tetanus Toxoid, Algeldrate) supplied by GNH India

Imovax (Td) Adult

Active Ingredient:
Diphtheria Toxoid, Tetanus Toxoid, Algeldrate
Origin:
EU

Imovax (Td) Adult (Diphtheria Toxoid, Tetanus Toxoid, Algeldrate)

Diphtheria toxoid and tetanus toxoid, the active ingredients in Imovax (Td) Adult, are vaccine components presented as an injectable solution for intramuscular or subcutaneous use. They stimulate protective immunity and are administered as booster immunizations against tetanus and diphtheria in adults.

GNH India supplies Imovax (Td) Adult as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide. The company adheres to global quality standards and provides cold‑chain logistics to ensure product integrity during transport. Customers receive regulatory documentation and support for import compliance.

Manufacturer / TM Owner

Sanofi Winthrop Industrie

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Indications & Clinical Uses

Imovax (Td) Adult is a tetanus‑diphtheria toxoid vaccine used for booster immunization in the adult population.

  • Tetanus: restores protective antibody levels against tetanus toxin in adults.
  • Diphtheria: restores protective antibody levels against diphtheria toxin in adults.
  • Combined Td booster: provides renewed immunity to both tetanus and diphtheria in the adult population.
  • Travel preparation: ensures immunity for adults traveling to regions with higher tetanus or diphtheria risk.

How It Works

  • The vaccine contains purified, inactivated tetanus and diphtheria toxoids adsorbed onto an aluminum‑based adjuvant (algeldrate). After intramuscular or subcutaneous injection, the toxoids are taken up by antigen‑presenting cells, processed and presented to T‑cells, prompting B‑cell activation and production of high‑affinity IgG antibodies that neutralize the respective bacterial toxins, thereby conferring protective immunity. The immune memory generated persists for several years, reducing the need for frequent re‑vaccination.

Side Effects

Imovax (Td) Adult may be associated with local and systemic reactions following injection.

Common Side Effects

  • Injection site pain: mild to moderate discomfort at the site of administration.
  • Redness or swelling: localized erythema or edema around the injection area.
  • Low‑grade fever: transient temperature rise, usually below 38.5 °C.
  • Headache: mild headache occurring within 24 hours post‑vaccination.
  • Fatigue: temporary feeling of tiredness or weakness.

Serious or Rare Side Effects

  • Anaphylaxis: severe allergic reaction requiring immediate medical attention.
  • Guillain‑Barré syndrome: rare neurological disorder characterized by muscle weakness.
  • High fever: temperature above 39 °C persisting more than 48 hours.
  • Seizures: convulsive episodes occurring shortly after vaccination.
  • Severe local reaction: extensive swelling or necrosis at injection site.

Precautions & Warnings

Before administering Imovax (Td) Adult, healthcare professionals should consider several precautionary measures.

  • Contraindication: avoid use in individuals with documented severe allergic reaction to any vaccine component.
  • Pregnancy: defer vaccination unless the benefit outweighs potential risk; consult obstetric guidance.
  • Immunocompromised: assess risk, as response may be reduced; vaccine is not live.
  • Acute illness: postpone vaccination if the patient has moderate or severe febrile illness.
  • Anticoagulant therapy: apply pressure post‑injection to minimize bleeding or hematoma.
  • Store at 2-8°C: keep refrigerated, protect from light, do not freeze or shake.

Avoid Interactions

Imovax (Td) Adult may interact with certain medications or medical conditions; awareness of these interactions helps ensure safe administration.

Major Interactions (Avoid)

  • Immunoglobulin therapy: may neutralize vaccine antigens, reducing immunogenicity.
  • Blood products: concurrent administration can impair antibody response.

Moderate Interactions (Monitor Closely)

  • Anticoagulants: increase risk of injection‑site bleeding; monitor for hematoma.
  • Corticosteroids: high‑dose therapy may diminish vaccine efficacy.
  • Antipyretics: prophylactic use may mask fever, but generally acceptable.

Frequently Asked Questions

Imovax (Td) Adult is indicated as a booster vaccine for adults to renew protective immunity against the toxins produced by tetanus and diphtheria bacteria. It is administered when the previously received primary series or earlier booster has waned, helping maintain adequate antibody levels.

The vaccine contains inactivated diphtheria and tetanus toxoids that are recognized as foreign by the immune system. After injection, antigen‑presenting cells process the toxoids and present them to T‑cells, which activate B‑cells to produce specific IgG antibodies. These antibodies neutralize the natural toxins if the person is later exposed.

The prescribing healthcare professional determines the appropriate dose and schedule. In routine practice, a single intramuscular injection of the vaccine is given in the deltoid muscle or an appropriate thigh site, with the interval between doses guided by the individual's immunization history.

Data on use of Td vaccines during pregnancy are limited, but the vaccine is not live and is generally considered safe when the benefit of preventing tetanus outweighs potential risks. Breastfeeding is not a contraindication; however, clinicians should evaluate each case and follow local guidelines.

Enquiries can be submitted on the product page at gnhindia.com by specifying the required quantity. GNH India supplies hospitals, pharmacies and procurement teams across international markets, verifies trade or institutional credentials, and then provides pricing, availability, cold‑chain shipping details and necessary import documentation.

Imovax (Td) Adult contains diphtheria and tetanus toxoids adsorbed onto an aluminum‑based adjuvant, similar to other Td formulations. Differences may lie in the specific adjuvant, preservative system, or manufacturing process, but all aim to elicit comparable protective antibody responses when administered according to recommended schedules.

The vaccine must be stored refrigerated between 2 °C and 8 °C. It should be kept in the original packaging, protected from light, and must not be frozen or shaken. Proper cold‑chain management during transport and storage is essential to maintain potency.

Imovax (Td) Adult is given by intramuscular injection, typically into the deltoid muscle of the upper arm or the anterolateral thigh in adults. Subcutaneous administration is also acceptable if intramuscular injection is not feasible, following aseptic technique.

Serious adverse events, although rare, include severe allergic reactions such as anaphylaxis and neurological conditions like Guillain‑Barré syndrome. Immediate medical attention is required if symptoms such as difficulty breathing, swelling of the face or throat, or rapid onset of muscle weakness occur after vaccination.

Individuals with a known severe allergy to any component of the vaccine, including the toxoids or the aluminum adjuvant, should not receive it. Persons who have experienced a previous severe reaction to a tetanus‑diphtheria vaccine should also avoid further doses until evaluated by a specialist.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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