Product image of Imozop (Zopiclone) supplied by GNH India

Imozop

Active Ingredient:
Zopiclone
Origin:
EU

Imozop (Zopiclone)

Zopiclone, the active ingredient in Imozop, is a cyclopyrrolone (non‑benzodiazepine hypnotic) presented as an oral tablet for oral use. It is indicated for the short‑term treatment of insomnia in adults who have difficulty falling or staying asleep.

GNH India supplies Imozop as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Sandoz A/S

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Indications & Clinical Uses

Zopiclone acts on the central nervous system to treat sleep disorders, particularly insomnia.

  • Insomnia (difficulty initiating sleep): helps patients fall asleep more quickly.
  • Insomnia (difficulty maintaining sleep): reduces nighttime awakenings and improves sleep continuity.
  • Transient sleep disturbance: provides temporary relief for short‑term sleep disruption.

How It Works

  • Zopiclone binds to the benzodiazepine site of the GABA‑A receptor complex as a positive allosteric modulator, enhancing the inhibitory effect of GABA. This increases chloride ion influx into neurons, leading to hyperpolarisation and a sedative‑hypnotic effect that facilitates sleep onset and maintenance.

Side Effects

Common Side Effects

  • Drowsiness: feeling unusually sleepy during the day.
  • Dry mouth: reduced salivary flow causing discomfort.
  • Bitter or unpleasant taste.
  • Headache: mild to moderate cranial pain.
  • Dizziness: sensation of light‑headedness or unsteadiness.
  • Nausea: mild stomach upset.

Serious or Rare Side Effects

  • Complex sleep behaviours: activities such as sleepwalking or driving while not fully awake.
  • Allergic reactions: rash, itching, swelling, or difficulty breathing.
  • Depression or mood changes: worsening depressive symptoms.
  • Memory impairment: difficulty recalling events after waking.

Precautions & Warnings

Before prescribing Zopiclone, clinicians should consider several safety factors.

  • Assess renal function: adjust use in severe impairment.
  • Avoid alcohol: concurrent use may increase sedation and respiratory depression.
  • Monitor for dependence: limit duration to the shortest effective period.
  • Caution in elderly: increased sensitivity to sedative effects and risk of falls.
  • Pregnancy and lactation: use only if benefits outweigh potential risks.
  • Store at ambient temperature below 25°C: keep in the original pack, protect from moisture.

Avoid Interactions

Zopiclone may interact with other substances that affect the central nervous system or its metabolism.

Major Interactions (Avoid)

  • Concomitant use with other CNS depressants (e.g., opioids, benzodiazepines): risk of profound sedation.
  • Strong CYP3A4 inhibitors (e.g., ketoconazole, itraconazole): may increase plasma concentrations.
  • Alcohol: additive CNS depression and impaired coordination.

Moderate Interactions (Monitor Closely)

  • CYP3A4 inducers (e.g., rifampicin, carbamazepine): may reduce therapeutic effect.
  • Antidepressants (e.g., fluoxetine, sertraline): may enhance sedative properties.
  • Antihistamines (e.g., diphenhydramine): may increase drowsiness and impair alertness.

Frequently Asked Questions

Imozop contains the active ingredient Zopiclone and is used for the short‑term treatment of insomnia. It helps adults who have difficulty falling asleep, staying asleep, or experience frequent nighttime awakenings.

Zopiclone acts as a positive allosteric modulator at the GABA‑A receptor. By enhancing the inhibitory action of GABA, it increases chloride influx into neurons, producing a sedative‑hypnotic effect that facilitates sleep initiation and maintenance.

The appropriate dose of Imozop is determined by the prescribing clinician based on the patient’s age, medical condition, and response to therapy. Dosage instructions are provided on the prescription label.

Zopiclone should be used in pregnancy or while breastfeeding only if the potential benefit justifies the potential risk to the fetus or infant. Healthcare providers typically evaluate the risk‑benefit profile before prescribing.

To place an order, submit an enquiry on the Imozop product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details, and any necessary import documentation.

Imozop (Zopiclone) belongs to the cyclopyrrolone class, offering a rapid onset of sleep with a relatively short half‑life. Compared with benzodiazepine hypnotics, it may have a lower risk of dependence but still requires careful monitoring for tolerance and withdrawal.

Imozop tablets should be stored at ambient temperature below 25 °C, in the original packaging, and protected from moisture and direct sunlight. Keep the product out of reach of children.

Imozop is taken orally, usually shortly before bedtime. Patients should follow the prescribing information and avoid taking the medication with or immediately after a heavy meal, as food can affect absorption.

Serious risks include complex sleep behaviours such as sleepwalking or driving while not fully awake, allergic reactions, and potential dependence with prolonged use. Patients should report any unusual activities or symptoms to their healthcare provider promptly.

Imozop is contraindicated in patients with known hypersensitivity to Zopiclone, severe hepatic impairment, or a history of severe sleep‑related behaviours. Caution is also advised for individuals with untreated sleep apnea, severe depression, or those taking interacting CNS depressants.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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