Product image of Inalacor Accuhaler (Fluticasone Propionate) supplied by GNH India

Inalacor Accuhaler

Active Ingredient:
Fluticasone Propionate
Origin:
EU

Inalacor Accuhaler (Fluticasone Propionate)

Fluticasone propionate, the active ingredient in Inalacor Accuhaler, is a corticosteroid presented as a dry powder inhaler for inhalation use. It reduces airway inflammation and hyper‑responsiveness, and is indicated for the long‑term management of asthma and chronic obstructive pulmonary disease (COPD) in adults and adolescents.

GNH India supplies Inalacor Accuhaler as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide. The company adheres to stringent quality standards and provides regulatory‑approved products to a global network of healthcare providers.

Manufacturer / TM Owner

Glaxosmithkline, S.A.

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Indications & Clinical Uses

Fluticasone propionate is a corticosteroid inhaled to control airway inflammation in respiratory diseases.

  • Asthma: improves symptom control and reduces the frequency of exacerbations.
  • Chronic obstructive pulmonary disease (COPD): decreases airway inflammation and helps maintain lung function.
  • Bronchial hyperresponsiveness: reduces airway sensitivity to triggers, supporting overall respiratory stability.

How It Works

  • Fluticasone propionate binds to intracellular glucocorticoid receptors, forming a complex that translocates to the nucleus and modulates gene transcription. This action suppresses the production of pro‑inflammatory cytokines, chemokines, and adhesion molecules, leading to reduced airway edema, mucus secretion, and hyper‑responsiveness, thereby improving airflow in the respiratory tract.

Side Effects

Common Side Effects

  • Oral thrush (candidiasis): fungal infection of the mouth.
  • Hoarseness or dysphonia: voice changes due to local irritation.
  • Cough or throat irritation: mild respiratory discomfort.
  • Headache: transient pain often unrelated to systemic exposure.

Serious or Rare Side Effects

  • Paradoxical bronchospasm: sudden worsening of breathing.
  • Adrenal suppression: reduced endogenous cortisol production.
  • Severe allergic reaction: anaphylaxis or angioedema requiring immediate medical attention.

Precautions & Warnings

Before initiating therapy, consider the following precautions:

  • Assess infection risk: evaluate for active respiratory infections prior to use.
  • Monitor growth in children: periodic assessment of height velocity is recommended.
  • Avoid abrupt discontinuation: taper the dose after long‑term therapy to prevent adrenal insufficiency.
  • Use mouth rinse: rinse and expectorate after inhalation to reduce oral candidiasis.
  • Store at ambient temperature: keep in the original container, protect from moisture and heat.

Avoid Interactions

Fluticasone propionate may interact with other medicines as follows:

Major Interactions (Avoid)

  • Strong CYP3A4 inhibitors (e.g., ketoconazole): may increase systemic corticosteroid exposure.
  • Systemic corticosteroids: additive immunosuppressive effects.
  • Live vaccines: reduced efficacy and increased infection risk.

Moderate Interactions (Monitor Closely)

  • Beta‑agonists: may mask bronchospasm symptoms.
  • Diuretics: potential for hypokalemia when combined with systemic steroids.
  • Antifungal azoles (moderate inhibitors): may modestly raise fluticasone levels.

Frequently Asked Questions

Inalacor Accuhaler contains fluticasone propionate, an inhaled corticosteroid prescribed for the long‑term management of asthma and chronic obstructive pulmonary disease (COPD). It helps control airway inflammation, reduces symptom frequency, and lowers the risk of disease exacerbations when used as part of a regular maintenance regimen.

Fluticasone propionate binds to glucocorticoid receptors inside airway cells, altering gene expression to suppress the release of inflammatory mediators such as cytokines and chemokines. This reduces airway swelling, mucus production, and hyper‑responsiveness, leading to improved airflow and fewer asthma or COPD symptoms.

The appropriate dose of Inalacor Accuhaler is determined by a qualified prescriber based on the patient’s age, disease severity, and response to therapy. Healthcare professionals tailor the number of inhalations per day to achieve optimal control while minimizing potential side effects.

Safety data for fluticasone propionate in pregnancy and lactation are limited. The medication should only be used if the potential benefit to the mother outweighs any possible risk to the fetus or infant. Pregnant or nursing patients should discuss treatment options with their healthcare provider.

To place an order, submit an enquiry on the product page at gnhindia.com specifying the required quantity of Inalacor Accuhaler. GNH India works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including any cold‑chain requirements), and necessary import documentation.

Inalacor Accuhaler delivers fluticasone propionate, a high‑potency corticosteroid with strong anti‑inflammatory activity. Compared with agents such as budesonide, fluticasone generally requires a lower daily dose to achieve similar clinical effects, but both classes share comparable safety profiles when used at recommended doses.

Store the inhaler at ambient temperature, away from direct sunlight and moisture. Keep it in the original packaging until use, and avoid exposing it to extreme heat or humidity. Do not refrigerate or freeze the device, as this could affect powder integrity.

To use the dry‑powder inhaler, remove the cap, exhale fully away from the device, place the mouthpiece between the lips, and inhale sharply and deeply. Hold the breath for about 10 seconds, then remove the inhaler and breathe out gently. Rinse the mouth after each dose to reduce the risk of oral thrush.

Serious adverse events, although rare, include paradoxical bronchospasm, adrenal suppression, severe allergic reactions such as anaphylaxis, and opportunistic infections like pneumonia. Patients should seek immediate medical attention if they experience sudden breathing difficulty, severe swelling, or signs of infection.

Inalacor Accuhaler is contraindicated in individuals with a known hypersensitivity to fluticasone propionate or any component of the inhaler. It should also be avoided in patients with untreated systemic fungal infections or those who have experienced a severe reaction to other inhaled corticosteroids.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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