Inaladuo Accuhaler (Fluticasone Propionate, Salmeterol)

Fluticasone propionate binds to glucocorticoid receptors in airway cells, suppressing inflammatory gene expression and decreasing cytokine production. Salmeterol activates β2‑adrenergic receptors on airway smooth muscle, increasing cyclic AMP levels and causing prolonged relaxation of the bronchial muscles. Together they reduce inflammation and keep the airways open for up to 12 hours.

The prescribed dose of Inaladuo Accuhaler is determined by the treating physician based on the patient’s age, disease severity, and response to therapy. Patients should follow the dosing instructions provided by their healthcare professional and not adjust the number of inhalations without medical guidance.

Safety data for Inaladuo Accuhaler in pregnancy and lactation are limited. The product should be used only if the potential benefit justifies any potential risk to the fetus or infant. Women who are pregnant, planning to become pregnant, or breastfeeding should discuss the risks and benefits with their healthcare provider.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India supplies hospitals, pharmacies and procurement teams across international markets. After the enquiry, the sales team will verify trade or institutional credentials, then respond with pricing, availability, shipping details (including any cold‑chain requirements) and the necessary import documentation.

Inaladuo Accuhaler delivers a fixed dose of fluticasone propionate and salmeterol via a dry‑powder inhaler, offering consistent dose delivery without the need for propellant. Compared with metered‑dose inhalers, the Accuhaler may provide higher lung deposition and is breath‑actuated, which can be advantageous for patients who have difficulty coordinating inhalation. Clinical efficacy and safety are comparable to other approved ICS/LABA combinations when used as directed.

Store the inhaler at ambient temperature, preferably below 25 °C, in its original packaging to protect it from moisture and direct sunlight. Keep the device out of reach of children. Do not expose it to extreme heat or humidity, and avoid crushing or puncturing the inhaler mechanism.

To use the Accuhaler, remove the device from its foil pouch, hold it upright, and slide the thumb grip to load a dose. Exhale fully away from the inhaler, place the mouthpiece between the lips, and inhale sharply and deeply. Hold the breath for about 10 seconds, then remove the inhaler and close the mouthpiece. Rinse the mouth with water after each use to reduce the risk of oral thrush.

Serious adverse events include paradoxical bronchospasm, which can cause sudden worsening of breathing, adrenal suppression with prolonged high‑dose use, and severe allergic reactions such as rash, urticaria or anaphylaxis. Patients should seek immediate medical attention if they experience any of these symptoms.

Inaladuo Accuhaler is contraindicated in patients with a known hypersensitivity to fluticasone propionate, salmeterol, or any component of the inhaler. It should also be avoided in individuals who have experienced a severe allergic reaction to other inhaled corticosteroids or long‑acting β2‑agonists. Patients with untreated infections or active tuberculosis should be evaluated before initiating therapy.