Product image of Inalgex (Etofenamate) supplied by GNH India

Inalgex

Active Ingredient:
Etofenamate
Origin:
EU

Inalgex (Etofenamate)

Etofenamate, the active ingredient in Inalgex, is a nonsteroidal anti-inflammatory drug (NSAID) presented as a topical formulation for cutaneous use. It is employed to relieve pain and reduce inflammation in musculoskeletal conditions, particularly where localized therapy is preferred.

GNH India supplies Inalgex as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide. The company adheres to stringent quality standards and provides regulatory documentation for global distribution. Customers benefit from reliable supply chains, batch traceability, and responsive technical support.

Manufacturer / TM Owner

Laboratórios Basi – Indústria Farmacêutica, S.A.

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Indications & Clinical Uses

Etofenamate acts locally on inflammatory pathways in soft‑tissue and joint disorders.

  • Rheumatoid arthritis: reduces joint pain and swelling in affected areas.
  • Osteoarthritis: alleviates chronic discomfort and improves joint mobility.
  • Sprains and strains: provides localized pain relief and diminishes inflammation of injured muscles and ligaments.

How It Works

  • Etofenamate inhibits cyclooxygenase (COX‑1 and COX‑2) enzymes in peripheral tissues, decreasing the synthesis of prostaglandins that mediate pain, inflammation, and fever. By limiting prostaglandin production at the site of application, it reduces vascular permeability and nociceptor sensitization, resulting in localized analgesic and anti‑inflammatory effects without significant systemic exposure.

Side Effects

Topical etofenamate may cause skin‑related reactions.

Common Side Effects

  • Skin irritation: burning or stinging sensation at the application site.
  • Erythema: redness of the treated area.
  • Pruritus: itching or mild rash.
  • Dryness: localized skin dryness or peeling.
  • Contact dermatitis: mild allergic skin reaction.

Serious or Rare Side Effects

  • Severe allergic reaction: angio‑edema or anaphylaxis.
  • Stevens‑Johnson syndrome or toxic epidermal necrolysis.
  • Systemic NSAID effects: gastrointestinal ulceration, bleeding, or renal impairment.
  • Hepatotoxicity: abnormal liver function tests.
  • Severe skin necrosis: ulceration or necrotic lesions at the site.

Precautions & Warnings

When using Inalgex, consider the following safety measures.

  • Assess skin integrity: avoid application on broken, infected, or irritated skin.
  • Monitor for hypersensitivity: discontinue use if rash, swelling, or systemic allergic signs appear.
  • Cardiovascular caution: use with care in patients with known heart disease or hypertension.
  • Concomitant NSAIDs: avoid using other systemic NSAIDs to reduce gastrointestinal risk.
  • Pregnancy and lactation: consult a healthcare professional before use.
  • Store at ambient temperature: keep in the original container, protect from moisture and light.

Avoid Interactions

Etofenamate may interact with other medicines; review the following.

Major Interactions (Avoid)

  • Systemic anticoagulants (e.g., warfarin): increased risk of bleeding.
  • Other NSAIDs or COX‑2 inhibitors: heightened gastrointestinal toxicity.
  • Corticosteroids: elevated chance of ulceration or bleeding.

Moderate Interactions (Monitor Closely)

  • Diuretics: possible reduction in renal clearance.
  • ACE inhibitors or ARBs: potential decline in renal function.
  • Lithium: NSAIDs may raise lithium serum levels, requiring monitoring.

Frequently Asked Questions

Inalgex contains the NSAID etofenamate and is applied to the skin to relieve pain and reduce inflammation in musculoskeletal conditions such as arthritis, sprains, and strains. It provides localized therapeutic effects without the need for systemic medication.

Etofenamate blocks cyclooxygenase enzymes (COX‑1 and COX‑2) in the skin and underlying tissues, which lowers prostaglandin production. Reduced prostaglandins diminish inflammation, swelling, and pain signals, delivering a targeted anti‑inflammatory and analgesic effect at the site of application.

The dosage of Inalgex is determined by the prescribing healthcare professional based on the specific condition, severity, and patient factors. The prescriber will specify the amount to apply, frequency, and duration of treatment.

Safety of topical etofenamate in pregnancy or lactation has not been fully established. Women who are pregnant, planning pregnancy, or breastfeeding should discuss potential risks with their healthcare provider before using Inalgex.

To request Inalgex, submit an enquiry on the product page at gnhindia.com, indicating the required quantity. GNH India works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details, and any necessary import documentation.

Inalgex delivers etofenamate, a potent NSAID with strong COX inhibition, similar to other topical agents like diclofenac or ketoprofen. Compared with some alternatives, etofenamate may offer a higher anti‑inflammatory potency, but individual response and tolerability can vary, so clinicians choose based on patient needs and safety profile.

Inalgex should be stored at ambient temperature, below 25 °C, in its original packaging. Keep the container tightly closed, protect it from moisture, direct sunlight, and extreme heat to maintain product stability.

Inalgex is applied topically to the affected skin area. The prescribed amount is spread thinly and gently massaged into the skin, usually 2–4 times daily, or as directed by the healthcare professional. Hands should be washed before and after application.

Serious risks include severe allergic reactions such as anaphylaxis, Stevens‑Johnson syndrome, toxic epidermal necrolysis, and systemic NSAID effects like gastrointestinal bleeding, renal impairment, or liver dysfunction. Patients should seek immediate medical attention if they notice signs of a severe reaction.

Inalgex should be avoided in individuals with known hypersensitivity to etofenamate or any component of the formulation, those with broken or infected skin at the intended site, and patients taking systemic anticoagulants or other NSAIDs without medical supervision.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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