Product image of Indapamid Stada (Indapamide) supplied by GNH India

Indapamid Stada

Active Ingredient:
Indapamide
Origin:
EU

Indapamid Stada (Indapamide)

Indapamide, the active ingredient in Indapamid Stada, is a thiazide‑like diuretic presented as an oral tablet for oral use. It treats hypertension and edema associated with congestive heart failure in adult patients, providing blood pressure control and fluid reduction under medical supervision.

GNH India supplies Indapamid Stada as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies, and clinics worldwide, with a focus on reliable quality, regulatory compliance, and timely delivery across multiple regions. Our global logistics network ensures consistent product availability and compliance with local regulatory requirements.

Manufacturer / TM Owner

Stadapharm Gmbh

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Indications & Clinical Uses

  • Indapamide is a thiazide‑like diuretic that lowers blood pressure and reduces fluid overload.
  • Hypertension: reduces systolic and diastolic pressure by promoting natriuresis.
  • Edema associated with congestive heart failure: decreases extracellular fluid volume, relieving peripheral swelling.
  • Renal impairment‑related hypertension: aids in blood pressure management when used with caution.

How It Works

  • Indapamide acts on the distal convoluted tubule of the nephron by inhibiting the Na⁺/Cl⁻ cotransporter. This blockade reduces sodium and chloride reabsorption, leading to increased urinary excretion of water and electrolytes. The resulting decrease in plasma volume lowers cardiac output, while a direct vasodilatory effect on peripheral arterioles reduces systemic vascular resistance, together contributing to blood pressure reduction.

Side Effects

Indapamide may cause a range of adverse reactions, varying from mild to severe.

Common Side Effects

  • Dizziness
  • Headache
  • Increased urination
  • Electrolyte imbalance (e.g., low potassium)
  • Nausea

Serious or Rare Side Effects

  • Severe dehydration
  • Hyponatremia or hypokalemia leading to cardiac arrhythmia
  • Gout attacks
  • Allergic reactions such as rash or angioedema
  • Blood dyscrasias (e.g., agranulocytosis)

Precautions & Warnings

  • When prescribing Indapamide, several safety considerations should be observed.
  • Monitor electrolytes: check serum potassium and sodium regularly.
  • Assess renal function: avoid use in severe renal impairment.
  • Avoid abrupt discontinuation: may cause rebound hypertension.
  • Pregnancy category B: use only if benefit outweighs risk.
  • Drug interactions: review concomitant medications for potential additive effects.
  • Store at ambient temperature: keep in the original container, protect from moisture and light.

Avoid Interactions

Indapamide can interact with other medicines, requiring attention to the level of risk.

Major Interactions (Avoid)

  • Lithium: may increase lithium toxicity.
  • NSAIDs: may reduce diuretic efficacy and impair renal function.
  • ACE inhibitors or ARBs: risk of severe hypotension and electrolyte imbalance.

Moderate Interactions (Monitor Closely)

  • Beta‑blockers: additive blood‑pressure‑lowering effect.
  • Digoxin: heightened risk of hypokalemia‑related toxicity.
  • Antidiabetic agents: may enhance hypoglycaemic response.

Frequently Asked Questions

Indapamid Stada contains indapamide, a thiazide‑like diuretic indicated for the treatment of hypertension and for reducing edema associated with congestive heart failure. It helps lower blood pressure and remove excess fluid in adult patients under medical supervision.

Indapamide inhibits the sodium‑chloride cotransporter in the distal convoluted tubule of the kidney, reducing reabsorption of these electrolytes. This promotes increased urinary excretion of water and salts, decreasing plasma volume and producing a direct vasodilatory effect that together lower systemic blood pressure.

The appropriate dose of indapamide is determined by the prescribing clinician based on the individual’s medical condition, response to therapy, and renal function. Dosage instructions are provided on the prescription label and should be followed exactly as directed by the healthcare professional.

Indapamide is classified as pregnancy category B, indicating that animal studies have not shown risk but there are no adequate human studies. It should be used during pregnancy only if the potential benefit justifies the potential risk. Limited data are available for breastfeeding, so a risk‑benefit assessment is required.

To place an order, submit an enquiry on the product page at gnhindia.com specifying the required quantity of Indapamid Stada. GNH India works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Indapamide belongs to the thiazide‑like class, offering a longer duration of action and a lower incidence of metabolic side effects compared with classic thiazides such as hydrochlorothiazide. It provides effective blood‑pressure control while often requiring a lower dose, but individual response and tolerance vary, so clinicians choose based on patient profile.

Store at ambient temperature: keep the tablets in the original packaging, protect them from moisture and light, and store them below 25 °C. Do not use the product if the packaging is damaged or if the tablets appear discoloured.

Indapamid Stada is taken orally, usually with a glass of water. It may be taken with or without food, but patients should follow the specific instructions on the prescription label and maintain consistent timing each day to ensure stable blood‑pressure control.

Serious risks include severe dehydration, significant electrolyte disturbances such as hyponatremia or hypokalemia that can lead to cardiac arrhythmias, gout attacks, and rare allergic reactions like angioedema. Patients should seek immediate medical attention if they experience symptoms such as rapid weight loss, muscle weakness, severe abdominal pain, or swelling of the face or throat.

Indapamid Stada should be avoided in patients with known hypersensitivity to indapamide or other sulfonamide diuretics, in those with severe renal impairment, and in individuals with anuria. Caution is also advised for patients with gout, severe electrolyte imbalances, or uncontrolled diabetes, and the drug should only be used under medical guidance in these cases.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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