Product image of Indapamid Stada (Indapamide) supplied by GNH India

Indapamid Stada

Active Ingredient:
Indapamide
Origin:
EU

Indapamid Stada (Indapamide)

Indapamide, the active ingredient in Indapamid Stada, is a thiazide‑like diuretic presented as an oral formulation for oral use. It is employed to lower high blood pressure and to reduce fluid accumulation in patients with heart failure or renal disease.

GNH India supplies Indapamid Stada as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Stada Arzneimittel Ag

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Indications & Clinical Uses

Indapamide is used in the management of cardiovascular and renal conditions where fluid overload or elevated blood pressure is present.

  • Hypertension: lowers systolic and diastolic blood pressure, decreasing cardiovascular risk.
  • Edema associated with heart failure: promotes diuresis to reduce fluid retention and improve symptoms.
  • Edema associated with renal disease: facilitates excess fluid removal, helping to control swelling and improve renal function.

How It Works

  • Indapamide inhibits sodium‑chloride reabsorption in the distal convoluted tubule by blocking the Na⁺/Cl⁻ cotransporter. This action increases urinary excretion of sodium and water, leading to reduced plasma volume and decreased peripheral vascular resistance, which together contribute to its antihypertensive and diuretic effects.

Side Effects

Indapamide may cause a range of adverse reactions, varying from mild to serious.

Common Side Effects

  • Increased urination: frequent need to void.
  • Electrolyte imbalance (especially low potassium): may cause muscle weakness.
  • Dizziness or light‑headedness: often related to blood pressure drop.
  • Headache: mild to moderate intensity.
  • Nausea or abdominal discomfort.
  • Fatigue: general feeling of tiredness.

Serious or Rare Side Effects

  • Severe dehydration: marked fluid loss requiring medical attention.
  • Hyponatremia or severe hypokalemia: dangerous electrolyte disturbances.
  • Allergic reactions: rash, itching, or swelling.
  • Blood dyscrasias: leukopenia or thrombocytopenia.
  • Acute pancreatitis: abdominal pain with elevated enzymes.
  • Profound hypotension: sudden, significant drop in blood pressure.

Precautions & Warnings

When prescribing Indapamide, clinicians should consider several safety measures.

  • Monitor electrolytes: check serum potassium and sodium regularly.
  • Assess renal function: evaluate creatinine and eGFR before and during therapy.
  • Use caution in hepatic impairment: dose adjustments may be needed.
  • Avoid in severe hypotension: may exacerbate low blood pressure.
  • Adjust dose in elderly patients: start low and monitor response.
  • Store at ambient temperature: keep below 25°C in the original container, protect from moisture.

Avoid Interactions

Indapamide can interact with other medicines, influencing efficacy or safety.

Major Interactions (Avoid)

  • Lithium: increased lithium levels may cause toxicity.
  • Cyclosporine: heightened risk of nephrotoxicity.
  • Other thiazide‑like diuretics: additive electrolyte disturbances.

Moderate Interactions (Monitor Closely)

  • ACE inhibitors or ARBs: may enhance hypotensive effect.
  • Digoxin: electrolyte shifts can predispose to digoxin toxicity.
  • Antidiabetic agents: risk of hypoglycemia may increase.

Frequently Asked Questions

Indapamid Stada contains indapamide, a thiazide‑like diuretic indicated for the treatment of hypertension and for reducing fluid overload in patients with edema due to heart failure or renal disease. It helps control blood pressure and alleviate swelling by promoting the excretion of excess salt and water.

Indapamide works by blocking the sodium‑chloride cotransporter in the distal convoluted tubule of the kidney. This inhibition reduces reabsorption of sodium and chloride, leading to increased urinary loss of these ions along with water. The resulting decrease in plasma volume and peripheral vascular resistance lowers blood pressure and reduces edema.

The appropriate dose of Indapamid Stada is determined by the prescribing healthcare professional based on the individual’s medical condition, response to therapy, and renal function. Dosage adjustments are made according to clinical guidelines and patient-specific factors; patients should follow the prescriber’s instructions exactly.

Safety of indapamide during pregnancy or lactation has not been definitively established. It should only be used if the potential benefit justifies the potential risk to the fetus or infant. Healthcare providers will evaluate the risk‑benefit profile before prescribing it to pregnant or nursing women.

To request Indapamid Stada, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including any cold‑chain requirements) and necessary import documentation.

Indapamide belongs to the thiazide‑like diuretic class and offers a longer duration of action with a lower incidence of metabolic disturbances compared with classic thiazides such as hydrochlorothiazide. It is often preferred when sustained blood‑pressure control and modest diuretic effect are needed, while still being effective for edema management.

Indapamid Stada should be stored at ambient temperature, preferably below 25 °C. Keep the product in its original packaging to protect it from moisture and light, and store it out of reach of children.

Indapamid Stada is taken orally, usually with a glass of water. The tablet should be swallowed whole and can be taken with or without food, unless the prescriber advises otherwise. Patients should follow the dosing schedule provided by their healthcare professional.

Serious risks include severe dehydration, significant electrolyte imbalances such as hyponatremia or hypokalemia, allergic reactions, and profound hypotension. Patients should be monitored for signs of these conditions, especially during the initial weeks of therapy or when combined with other medications that affect fluid and electrolyte balance.

Indapamid Stada is contraindicated in patients with known hypersensitivity to indapamide or other sulfonamide-derived drugs, in those with severe renal impairment, and in individuals with anuria. Caution is also advised for patients with severe liver disease, uncontrolled diabetes, or those taking medications that may cause dangerous electrolyte disturbances.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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