Product image of Indapamid Teva (Indapamide) supplied by GNH India

Indapamid Teva

Active Ingredient:
Indapamide
Origin:
EU

Indapamid Teva (Indapamide)

Indapamide, the active ingredient in Indapamid Teva, is a thiazide‑like diuretic presented as an oral tablet for oral use. It is prescribed to lower elevated blood pressure and to reduce fluid accumulation in patients with edema secondary to congestive heart failure, primarily in adult populations.

GNH India supplies Indapamid Teva as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide. The company adheres to strict quality standards and provides regulatory documentation to support global distribution across multiple regulatory jurisdictions.

Manufacturer / TM Owner

Teva B.V

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Indications & Clinical Uses

  • Indapamide, a thiazide‑like diuretic, is employed in the management of conditions characterized by elevated blood pressure or fluid overload.
  • Hypertension: lowers systolic and diastolic blood pressure by promoting sodium and water excretion.
  • Edema associated with congestive heart failure: reduces peripheral swelling and pulmonary congestion through increased diuresis.
  • Hypertensive nephropathy: assists in controlling blood pressure and may slow progression of kidney damage.
  • Primary hypertension in adults: provides long‑lasting blood‑pressure control with once‑daily dosing.

How It Works

  • Indapamide acts on the distal convoluted tubule of the kidney by inhibiting the Na+/Cl- cotransporter. This blockade reduces reabsorption of sodium and chloride, leading to increased urinary excretion of water and electrolytes, a decrease in extracellular fluid volume, and ultimately a reduction in arterial blood pressure.

Side Effects

Indapamide may cause a range of adverse reactions, from mild to severe. Monitoring and prompt reporting of symptoms are recommended.

Common Side Effects

  • Dizziness or light‑headedness, especially after the first doses.
  • Increased frequency of urination due to its diuretic action.
  • Headache that may accompany changes in blood pressure.
  • Low potassium levels (hypokalemia) detectable on laboratory testing.

Serious or Rare Side Effects

  • Severe dehydration leading to hypotension.
  • Significant electrolyte imbalance such as hyponatremia or marked hypokalemia.
  • Allergic reactions including rash, angioedema, or anaphylaxis.

Precautions & Warnings

Before initiating therapy, clinicians should evaluate patient‑specific factors and monitor relevant parameters.

  • Monitor electrolyte levels: regular blood tests for sodium and potassium are advised.
  • Assess renal function: adjust use in patients with impaired kidney function.
  • Evaluate blood pressure: avoid excessive hypotension, especially in the elderly.
  • Use cautiously in gout: indapamide may raise serum uric acid.
  • Contraindicated in anuria: do not prescribe to patients with no urine output.
  • Store at below 25°C: keep in the original pack, protect from moisture and direct sunlight.

Avoid Interactions

Indapamide can interact with several drug classes, requiring careful management.

Major Interactions (Avoid)

  • Lithium: indapamide can increase lithium concentrations, raising toxicity risk.
  • NSAIDs: may diminish diuretic efficacy and impair renal function.
  • ACE inhibitors or ARBs: combined use can cause excessive potassium elevation.

Moderate Interactions (Monitor Closely)

  • Antidiabetic agents: indapamide may enhance hypoglycemic effects.
  • Corticosteroids: may counteract diuretic action and affect electrolyte balance.
  • Thyroid hormones: may increase risk of electrolyte loss; monitor thyroid function tests.
  • Antimicrobials such as quinolones: may increase risk of QT prolongation when combined.

Frequently Asked Questions

Indapamid Teva contains indapamide, a thiazide‑like diuretic prescribed to lower high blood pressure and to reduce fluid buildup in patients with congestive heart‑failure‑related edema. It is administered orally under medical supervision.

Indapamide blocks the sodium‑chloride transporter in the distal convoluted tubule of the kidney, decreasing reabsorption of Na⁺ and Cl⁻. This promotes excretion of water and salts, leading to reduced plasma volume and lower arterial pressure.

The specific dose and dosing schedule are determined by the prescribing clinician based on the individual’s condition, renal function, and response to therapy. Patients should follow the prescriber’s instructions and not adjust the dose on their own.

Safety data for indapamide during pregnancy and lactation are limited. It should only be used if the potential benefit justifies the possible risk to the fetus or infant, and the decision must be made by a qualified healthcare professional.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details, and any necessary import documentation.

Indapamide belongs to the thiazide‑like class, offering a longer duration of action and a lower incidence of metabolic disturbances compared with classic thiazide diuretics such as hydrochlorothiazide. It is often chosen when a sustained blood‑pressure‑lowering effect with fewer electrolyte shifts is desired.

Store the product at temperatures below 25 °C, in its original packaging, protected from moisture and direct sunlight. Keep it out of reach of children and do not use after the expiration date.

The medication is taken orally, usually once daily in the morning, with or without food as directed by the prescriber. Swallow the tablet whole with a full glass of water; do not crush or chew unless instructed otherwise.

The most concerning adverse events include severe dehydration, significant electrolyte imbalances such as hyponatremia or hypokalemia, and rare allergic reactions like rash, angioedema, or anaphylaxis. Patients should seek immediate medical attention if they experience symptoms such as dizziness, muscle cramps, or swelling.

Indapamide is contraindicated in patients with anuria, severe renal impairment, or known hypersensitivity to the drug. Caution is also advised for individuals with gout, hepatic disease, or those taking interacting medications; a healthcare professional should evaluate suitability before prescribing.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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