Product image of Indapamida Teva (Indapamide) supplied by GNH India

Indapamida Teva

Active Ingredient:
Indapamide
Origin:
EU

Indapamida Teva (Indapamide)

Indapamide, the active ingredient in Indapamida Teva, is a thiazide‑like diuretic presented as an oral tablet for oral use. It is employed to lower elevated blood pressure and to reduce fluid retention in patients with heart‑related edema. It is indicated for adult patients and is available in the European market under a prescription‑only status.

GNH India supplies Indapamida Teva as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide. The company adheres to Good Distribution Practice standards and provides regulatory‑compliant sourcing for global markets.

Manufacturer / TM Owner

Teva Pharma – Produtos Farmacêuticos Lda

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Indications & Clinical Uses

  • Indapamide is used primarily in cardiovascular conditions that require reduction of blood pressure or fluid overload.
  • Hypertension: Helps achieve target blood pressure levels and reduces cardiovascular risk.
  • Edema associated with congestive heart failure: Promotes fluid loss to alleviate swelling and improve symptom burden.

How It Works

  • Indapamide acts on the distal convoluted tubule of the nephron by inhibiting the Na⁺/Cl⁻ symporter. This blockade reduces sodium and chloride reabsorption, leading to increased urinary excretion of sodium (natriuresis) and water (diuresis). The resulting decrease in extracellular fluid volume lowers cardiac preload and systemic vascular resistance, contributing to its antihypertensive effect. Additionally, indapamide possesses mild vasodilatory properties that further aid blood pressure reduction.

Side Effects

Indapamide may cause a range of adverse reactions, varying from mild to serious.

Common Side Effects

  • Dizziness or light‑headedness
  • Increased urination
  • Electrolyte disturbances (e.g., low potassium)
  • Nausea or abdominal discomfort

Serious or Rare Side Effects

  • Severe dehydration or electrolyte imbalance
  • Acute kidney injury
  • Allergic reactions such as rash or angioedema
  • Blood dyscrasias (e.g., leukopenia)

Precautions & Warnings

When prescribing indapamide, clinicians should consider several precautionary measures to ensure safe use.

  • Monitor electrolytes: Check serum potassium and sodium regularly, especially in patients on other diuretics.
  • Assess renal function: Evaluate creatinine clearance before initiation and during therapy.
  • Caution in gout: Use with care as uric acid levels may rise.
  • Avoid abrupt discontinuation: Gradual dose reduction helps prevent rebound hypertension.
  • Pregnancy and lactation: Use only if clearly needed; limited data are available.
  • Store at ambient temperature: Keep below 25°C in the original container, protect from moisture and light.

Avoid Interactions

Indapamide can interact with several medicines, altering its efficacy or safety profile.

Major Interactions (Avoid)

  • Lithium: Increased lithium levels may cause toxicity.
  • NSAIDs: May reduce diuretic effect and worsen renal function.
  • ACE inhibitors or ARBs: Combined use can lead to significant potassium loss and renal impairment.

Moderate Interactions (Monitor Closely)

  • Antidiabetic drugs: May enhance hypoglycaemic effect.
  • Other antihypertensives: Additive blood pressure lowering, risk of hypotension.
  • Corticosteroids: Can counteract diuretic effect and affect electrolyte balance.

Frequently Asked Questions

Indapamida Teva contains indapamide, which is prescribed to lower high blood pressure (hypertension) and to reduce fluid buildup (edema) in patients with congestive heart failure. These uses stem from its ability to promote the excretion of sodium and water, thereby decreasing blood volume and vascular resistance.

Indapamide works by blocking the sodium‑chloride symporter located in the distal convoluted tubule of the kidney. This inhibition reduces reabsorption of sodium and chloride, leading to increased urinary loss of these ions along with water. The resulting drop in extracellular fluid volume lowers cardiac preload and systemic vascular resistance, helping to control blood pressure.

The appropriate dose of Indapamida Teva is determined by the prescribing healthcare professional based on the individual’s medical condition, response to therapy, and other factors. Patients should follow the prescriber’s instructions and not adjust the dose without medical guidance.

Safety data for indapamide in pregnancy and lactation are limited. It should only be used if the potential benefit justifies the potential risk to the fetus or infant, and the decision must be made by a qualified healthcare provider after evaluating the specific circumstances.

To request Indapamida Teva, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details, and any necessary import documentation.

Indapamide belongs to the thiazide‑like diuretic class and shares many actions with traditional thiazides, such as promoting natriuresis. Compared with some thiazides, indapamide has a longer half‑life and may cause fewer metabolic disturbances, but individual response varies, and choice of therapy should be guided by clinical judgment.

Indapamida Teva should be stored at ambient temperature, preferably below 25 °C. Keep the tablets in their original packaging, protect them from moisture and direct light, and store them out of reach of children.

Indapamida Teva is taken orally, usually with a glass of water. The tablet should be swallowed whole and not crushed or chewed unless otherwise directed by a healthcare professional.

Serious risks include severe dehydration, electrolyte imbalances (especially low potassium), acute kidney injury, and rare allergic reactions such as rash or angioedema. Patients should be monitored for signs of these conditions and seek medical attention if they occur.

Indapamida Teva is contraindicated in patients with known hypersensitivity to indapamide or other sulfonamide diuretics, severe renal impairment, and in those who have experienced severe electrolyte disturbances that cannot be corrected. Clinicians should evaluate each patient’s medical history before prescribing.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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