Product image of Indapamide Orion (Indapamide) supplied by GNH India

Indapamide Orion

Active Ingredient:
Indapamide
Origin:
EU

Indapamide Orion (Indapamide)

Indapamide, the active ingredient in Indapamide Orion, is a thiazide-like diuretic presented as a tablet for oral use. It treats hypertension and edema associated with congestive heart failure in adult patients.

GNH India supplies Indapamide Orion as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Orion Corporation

1
Pack/s
This product is added to your enquiry list

Request a Quote

Please fill out the form below and our team will get back to you shortly with pricing and further information.

A minimum order value applies. Our team will confirm the exact amount or quantity after reviewing your requirements.

Indications & Clinical Uses

  • Indapamide Orion is a thiazide‑like diuretic used in the management of cardiovascular fluid‑related conditions.
  • Hypertension: lowers systolic and diastolic blood pressure in patients with primary hypertension.
  • Edema associated with congestive heart failure: reduces fluid accumulation and peripheral swelling.
  • Secondary hypertension: assists in controlling blood pressure when elevated due to other underlying disorders.

How It Works

  • Indapamide inhibits sodium‑chloride reabsorption in the distal convoluted tubule of the nephron, leading to increased excretion of sodium, chloride, and water. This diuretic effect reduces plasma volume, decreases peripheral vascular resistance, and ultimately lowers arterial blood pressure, while also alleviating fluid overload in heart‑failure states.

Side Effects

Indapamide may cause a range of adverse reactions, from mild to severe.

Common Side Effects

  • Dizziness or light‑headedness
  • Headache
  • Increased urinary frequency
  • Electrolyte disturbances such as low potassium
  • Fatigue or muscle cramps

Serious or Rare Side Effects

  • Severe dehydration or electrolyte imbalance
  • Hyponatremia or hyperuricemia
  • Allergic reactions including rash or angioedema
  • Pancreatitis or blood dyscrasias such as agranulocytosis

Precautions & Warnings

  • Before initiating therapy with Indapamide Orion, several safety considerations should be observed.
  • Monitor electrolytes: check serum potassium and sodium regularly.
  • Assess renal function: evaluate creatinine clearance before and during treatment.
  • Avoid abrupt discontinuation: taper dose to prevent rapid fluid shifts.
  • Use caution in elderly: increased susceptibility to hypotension and electrolyte loss.
  • Avoid use in severe hepatic impairment: limited data on safety.
  • Store at below 25°C: keep in the original container, protect from moisture and direct sunlight.

Avoid Interactions

Indapamide Orion can interact with several other medicines; awareness of the interaction level guides clinical decisions.

Major Interactions (Avoid)

  • Lithium: may increase lithium concentrations and toxicity.
  • NSAIDs: can blunt the diuretic effect and impair renal function.
  • ACE inhibitors or ARBs: heightened risk of hypotension and renal impairment.

Moderate Interactions (Monitor Closely)

  • Beta‑blockers: additive blood‑pressure lowering effect.
  • Antidiabetic agents: potential enhancement of hypoglycaemia.
  • Corticosteroids: may exacerbate potassium loss and electrolyte disturbances.

Frequently Asked Questions

Indapamide Orion is prescribed to manage high blood pressure (hypertension) and to reduce fluid buildup (edema) in patients with congestive heart failure. It may also be used for secondary forms of hypertension when blood pressure elevation is linked to other medical conditions.

Indapamide blocks the reabsorption of sodium and chloride ions in the distal convoluted tubule of the kidney. This promotes the excretion of water and salts, decreasing blood volume and peripheral vascular resistance, which together lower arterial blood pressure.

The appropriate dose of Indapamide Orion is determined by the prescribing clinician based on the individual’s medical condition, response to therapy, and renal function. Patients should follow the dosage instructions provided by their healthcare professional.

Safety data for indapamide in pregnancy and lactation are limited. It should only be used if the potential benefit justifies any possible risk to the fetus or infant, and the decision must be made by a qualified healthcare provider.

To place an order, submit an enquiry on the product page at gnhindia.com specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Indapamide belongs to the thiazide‑like diuretic class, offering a longer duration of action and a more favorable metabolic profile compared with traditional thiazides. It is often chosen for patients who need effective blood‑pressure control with a lower risk of potassium loss.

Indapamide Orion should be stored at temperatures below 25 °C in its original packaging, protected from moisture and direct sunlight. Do not store in areas with high humidity or extreme heat to maintain product stability.

Indapamide Orion is taken orally, usually with a glass of water. It can be taken with or without food, but patients should follow the specific instructions given by their prescriber to ensure consistent absorption.

Serious risks include severe dehydration, electrolyte imbalances such as hyponatremia or hypokalemia, and rare allergic reactions that may present as rash, swelling, or difficulty breathing. Prompt medical attention is required if any of these symptoms occur.

Indapamide Orion is contraindicated in patients with known hypersensitivity to indapamide or other sulfonamide diuretics, and in those with severe renal or hepatic impairment where the drug’s safety has not been established.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

Disclaimer

At GNH India, we aim to provide information that is expert-reviewed, accurate, and reliable. However, all content on this platform is intended for general informational purposes only and does not constitute professional medical advice, diagnosis, or treatment. While efforts are made to maintain accuracy and currency, the information may contain errors, omissions, or may not reflect the latest developments. Always consult a qualified healthcare professional regarding any medical concerns.

All product names, brand names, trademarks and registered trademarks displayed on this website are the property of their respective owners. This website and its operator are not affiliated with, endorsed by, or authorized by any such trade mark owners unless expressly stated. Any reference to product names or trademarks is made solely for descriptive and informational purposes. No commercial relationship, sponsorship, approval, or association with any trademark owner should be inferred. Information provided herein does not constitute promotion, advertising, or an offer for sale of any medicinal product and is intended solely for general informational purposes.

All trademarks and brand names displayed on this website are used strictly in accordance with the provisions of the Trade Marks Act, 1999, specifically Sections 30 and 30(1) governing fair use. Trademark ownership has been accurately attributed under the "Manufacturer/ TM Owner" section in compliance with statutory requirements.

Related Products

Other formulations containing Indapamide

A

A
A

A
A

A
A

A

Browse all products →

Ordering Process

Simple, Secure, and Seamless

Learn how our streamlined ordering process guarantees fast, compliant, and reliable access to essential medicines worldwide.

Quote request form

01

Submit Quote Request Form

Tell us what medications you need by filling out our simple form and uploading a valid document.

Price estimate review

02

We Review & Send Estimate

Our licensed pharmacists will verify your details and provide you with a detailed cost estimate.

Secure payment

03

Confirm & Make Payment

Discuss any queries, approve the estimate, and complete your payment.

Worldwide delivery

04

Get Delivered

Your medicines, safely packed and delivered to your door or nearest airport — hassle-free.

Regulatory recognitions

Quality You Can Trust

Our internationally recognized certifications underscore our commitment to safety, quality, and excellence.

SGS GSDP Certification

GSDP Compliant from SGS

URS ISO 9001

URS ISO 9001 Certification

FDA Maharashtra

Licensed by FDA Maharashtra

IEC License DGFT

IEC License issued by DGFT