Product image of Inderal (Propranolol Hydrochloride) supplied by GNH India

Inderal

Active Ingredient:
Propranolol Hydrochloride
Origin:
EU

Inderal (Propranolol Hydrochloride)

Propranolol, the active ingredient in Inderal, is a beta blocker presented as an oral tablet for systemic use. It reduces heart rate and blood pressure and is employed in the management of hypertension, angina, cardiac arrhythmias, myocardial infarction prophylaxis, migraine prevention, and essential tremor.

GNH India supplies Inderal as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide, providing reliable quality and regulatory compliance for global markets, including Europe, Asia and Africa, and adhering to stringent pharmacopeial standards.

Manufacturer / TM Owner

Atnahs Pharma Netherlands B.V.

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Indications & Clinical Uses

Inderal (propranolol) is a non‑selective beta‑adrenergic blocker used to manage several cardiovascular and neurologic conditions.

  • Hypertension: lowers blood pressure and reduces cardiovascular risk.
  • Angina pectoris: decreases myocardial oxygen demand to relieve chest pain.
  • Cardiac arrhythmias: stabilises heart rhythm by slowing conduction.
  • Myocardial infarction prophylaxis: reduces the chance of recurrent heart attacks.
  • Migraine prophylaxis: prevents migraine attacks by modulating vascular tone.
  • Essential tremor: diminishes tremor amplitude in patients.

How It Works

  • Propranolol blocks beta‑1 and beta‑2 adrenergic receptors throughout the body, preventing catecholamines such as epinephrine and norepinephrine from binding. This antagonism reduces heart rate, myocardial contractility, and renin release, leading to lower cardiac output and blood pressure. In the central nervous system, beta‑blockade modulates neuronal excitability, contributing to migraine prevention and tremor control.

Side Effects

Common Side Effects

  • Fatigue or tiredness.
  • Dizziness or light‑headedness.
  • Cold hands and feet.
  • Nausea or stomach upset.
  • Sleep disturbances, including vivid dreams.
  • Mild depression.

Serious or Rare Side Effects

  • Bradycardia or severe slowing of heart rate.
  • Marked hypotension.
  • Heart block or worsening arrhythmias.
  • Bronchospasm, especially in asthmatic patients.
  • Severe hypoglycaemia in diabetic individuals.
  • Allergic reactions such as rash, swelling, or anaphylaxis.

Precautions & Warnings

Before starting Inderal, consider the following safety measures:

  • Cardiac assessment: evaluate heart rate, blood pressure, and conduction abnormalities.
  • Respiratory review: avoid use in uncontrolled asthma or severe chronic obstructive pulmonary disease.
  • Diabetes monitoring: watch for masking of hypoglycaemia symptoms.
  • Thyroid status: adjust dose in hyperthyroid patients.
  • Pregnancy and lactation: discuss risks with a healthcare professional.
  • Store at room temperature: keep in the original container, protect from moisture and light.

Avoid Interactions

Propranolol can interact with several medicines; monitoring is essential.

Major Interactions (Avoid)

  • Other beta‑blockers: additive bradycardia and hypotension.
  • Calcium channel blocker verapamil: risk of severe heart block.
  • Insulin or oral hypoglycaemic agents: may potentiate hypoglycaemia.

Moderate Interactions (Monitor Closely)

  • ACE inhibitors or ARBs: possible enhanced blood pressure lowering.
  • Diuretics: may increase risk of electrolyte imbalance.
  • NSAIDs: can reduce antihypertensive effect of propranolol.

Frequently Asked Questions

Inderal, containing propranolol, is prescribed for high blood pressure, chest pain due to angina, various cardiac rhythm disorders, prevention of repeat heart attacks, migraine prevention, and essential tremor. It works across cardiovascular and neurologic pathways to control symptoms and reduce the risk of complications.

Propranolol blocks both beta‑1 and beta‑2 adrenergic receptors, preventing natural stress hormones from stimulating the heart and blood vessels. This leads to a slower heart rate, reduced contractility, and lower blood pressure. In the brain, beta‑blockade helps stabilise neuronal activity, which contributes to migraine and tremor control.

The specific dose of Inderal is determined by the prescribing clinician based on the individual’s medical condition, age, weight, and response to therapy. Patients should follow the dosage instructions provided by their healthcare professional and not adjust the amount without medical guidance.

Safety of propranolol during pregnancy or while nursing should be evaluated by a qualified healthcare provider. The drug may cross the placenta and enter breast milk, so a prescriber will weigh potential benefits against possible risks to the fetus or infant before recommending use.

To request Inderal, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Inderal (propranolol) is a non‑selective beta‑blocker, meaning it blocks both beta‑1 and beta‑2 receptors, unlike cardio‑selective agents that primarily affect beta‑1. This broader activity can be advantageous for migraine and tremor but may require caution in patients with respiratory conditions where beta‑2 blockade could worsen symptoms.

Inderal should be stored at room temperature, ideally below 25 °C. Keep the tablets in their original packaging, protect them from moisture and direct sunlight, and ensure the container is tightly closed to maintain product stability throughout its shelf life.

Inderal is taken orally, usually with a glass of water. Depending on the formulation, it may be swallowed whole or, if a tablet, can be split only if the prescribing information allows. Patients should follow the timing and food instructions given by their prescriber.

The most serious risks include severe bradycardia, marked hypotension, heart block, bronchospasm in patients with asthma or COPD, and masking of hypoglycaemia symptoms in diabetics. Any sudden chest pain, fainting, or difficulty breathing should prompt immediate medical attention.

Inderal is contraindicated in individuals with known hypersensitivity to propranolol, severe bradycardia, second‑ or third‑degree heart block without a pacemaker, uncontrolled asthma, and certain types of heart failure. Patients with these conditions should discuss alternative therapies with their healthcare provider.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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