Product image of Indocollyre (Indometacin) supplied by GNH India

Indocollyre

Active Ingredient:
Indometacin
Origin:
EU

Indocollyre (Indometacin)

Indometacin, the active ingredient in Indocollyre, is a non‑steroidal anti‑inflammatory drug presented as an ophthalmic solution for ocular use. It reduces inflammation and pain in the eye by inhibiting prostaglandin synthesis, making it useful after surgery or in inflammatory eye conditions.

GNH India supplies Indocollyre as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Bausch + Lomb Ireland Limited

1
Pack/s
This product is added to your enquiry list

Request a Quote

Please fill out the form below and our team will get back to you shortly with pricing and further information.

A minimum order value applies. Our team will confirm the exact amount or quantity after reviewing your requirements.

Indications & Clinical Uses

Indometacin ophthalmic solution is employed to manage ocular inflammation and related discomfort. It acts locally to control prostaglandin‑mediated processes in the eye.

  • Post‑operative ocular inflammation: reduces swelling and pain after eye surgery.
  • Anterior uveitis: helps control intra‑ocular inflammation and discomfort.
  • Allergic conjunctivitis: alleviates redness, itching and swelling caused by allergic reactions.

How It Works

  • Indometacin inhibits cyclooxygenase‑1 and cyclooxygenase‑2 enzymes in ocular tissues, decreasing the conversion of arachidonic acid to prostaglandins. The reduced prostaglandin levels limit vascular permeability, leukocyte infiltration, and nociceptor activation, thereby diminishing inflammation and pain within the eye.

Side Effects

Indometacin ophthalmic solution may cause local adverse reactions.

Common Side Effects

  • Stinging or burning sensation upon instillation.
  • Transient blurred vision.
  • Increased tearing or watery discharge.
  • Conjunctival hyperemia (redness).
  • Mild ocular irritation.

Serious or Rare Side Effects

  • Corneal epithelial defects or ulceration.
  • Persistent intra‑ocular pressure elevation.
  • Severe allergic reaction (e.g., angio‑edema of the eyelid).
  • Vision loss due to corneal toxicity.
  • Endophthalmitis (infection inside the eye).

Precautions & Warnings

Before using Indocollyre, consider the following safety measures.

  • Allergy assessment: avoid if known hypersensitivity to indometacin or other NSAIDs.
  • Corneal health: do not use in patients with active corneal epithelial defects.
  • Intra‑ocular pressure: monitor patients with glaucoma or ocular hypertension.
  • Systemic NSAID use: limit concurrent systemic NSAIDs to reduce systemic exposure.
  • Pregnancy and lactation: use only if clearly needed and prescribed by a specialist.
  • Store at room temperature: keep in the original container, protect from light and moisture.

Avoid Interactions

Indometacin ophthalmic solution can interact with other medications, requiring attention to avoid adverse outcomes.

Major Interactions (Avoid)

  • Systemic anticoagulants (e.g., warfarin): increased risk of bleeding.
  • Systemic corticosteroids: heightened risk of ocular complications.
  • Other topical NSAIDs: additive toxicity to corneal epithelium.

Moderate Interactions (Monitor Closely)

  • Systemic NSAIDs: potential for cumulative prostaglandin inhibition.
  • Beta‑blocker eye drops: possible additive reduction in intra‑ocular pressure.
  • Anticholinergic eye drops: may affect tear film stability.

Frequently Asked Questions

Indocollyre is an ophthalmic solution containing indometacin, used to treat inflammation and pain in the eye after surgery, in anterior uveitis, and in allergic conjunctivitis. It works locally to reduce prostaglandin‑mediated swelling and discomfort.

Indometacin blocks cyclooxygenase‑1 and cyclooxygenase‑2 enzymes in ocular tissues, preventing the formation of prostaglandins. Lower prostaglandin levels reduce vascular leakage, leukocyte migration, and nerve activation, which together lessen inflammation and pain within the eye.

The dosing regimen for Indocollyre is determined by the prescribing eye‑care professional based on the specific condition, severity, and patient factors. The prescriber will specify the number of drops, frequency, and duration of treatment.

Indocollyre should be used during pregnancy or lactation only if the potential benefit justifies the potential risk. Healthcare providers will evaluate the individual situation and may recommend alternative therapies when safety cannot be assured.

To order Indocollyre, submit an enquiry on the product page at gnhindia.com, indicating the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Indocollyre (indometacin) is a non‑steroidal anti‑inflammatory eye drop, offering rapid pain relief and inflammation control without the steroid‑related rise in intra‑ocular pressure. Compared with corticosteroid drops, it carries a lower risk of steroid‑induced glaucoma but may have higher local irritation potential.

Indocollyre should be stored at room temperature, below 25 °C, in its original container. Keep the bottle tightly closed, protect it from direct light and moisture, and discard any solution that appears discolored or cloudy.

Indocollyre is applied as eye drops. The patient tilts the head back, pulls down the lower eyelid to create a pocket, and instills the prescribed number of drops. The eye should be closed gently for a few seconds to allow absorption, avoiding blinking or rubbing.

Serious risks include corneal epithelial defects or ulceration, significant intra‑ocular pressure elevation, severe allergic reactions such as angio‑edema, and rare cases of vision loss due to corneal toxicity. Prompt medical attention is required if any of these symptoms occur.

Indocollyre should not be used by individuals with known hypersensitivity to indometacin or other NSAIDs, those with active corneal epithelial defects, or patients with uncontrolled glaucoma without specialist advice. It is also contraindicated in eyes with severe infection unless directed by a clinician.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

Disclaimer

At GNH India, we aim to provide information that is expert-reviewed, accurate, and reliable. However, all content on this platform is intended for general informational purposes only and does not constitute professional medical advice, diagnosis, or treatment. While efforts are made to maintain accuracy and currency, the information may contain errors, omissions, or may not reflect the latest developments. Always consult a qualified healthcare professional regarding any medical concerns.

All product names, brand names, trademarks and registered trademarks displayed on this website are the property of their respective owners. This website and its operator are not affiliated with, endorsed by, or authorized by any such trade mark owners unless expressly stated. Any reference to product names or trademarks is made solely for descriptive and informational purposes. No commercial relationship, sponsorship, approval, or association with any trademark owner should be inferred. Information provided herein does not constitute promotion, advertising, or an offer for sale of any medicinal product and is intended solely for general informational purposes.

All trademarks and brand names displayed on this website are used strictly in accordance with the provisions of the Trade Marks Act, 1999, specifically Sections 30 and 30(1) governing fair use. Trademark ownership has been accurately attributed under the "Manufacturer/ TM Owner" section in compliance with statutory requirements.

Related Products

Other formulations containing Indometacin

A

A
A

A
A

A
A

A

Browse all products →

Ordering Process

Simple, Secure, and Seamless

Learn how our streamlined ordering process guarantees fast, compliant, and reliable access to essential medicines worldwide.

Quote request form

01

Submit Quote Request Form

Tell us what medications you need by filling out our simple form and uploading a valid document.

Price estimate review

02

We Review & Send Estimate

Our licensed pharmacists will verify your details and provide you with a detailed cost estimate.

Secure payment

03

Confirm & Make Payment

Discuss any queries, approve the estimate, and complete your payment.

Worldwide delivery

04

Get Delivered

Your medicines, safely packed and delivered to your door or nearest airport — hassle-free.

Regulatory recognitions

Quality You Can Trust

Our internationally recognized certifications underscore our commitment to safety, quality, and excellence.

SGS GSDP Certification

GSDP Compliant from SGS

URS ISO 9001

URS ISO 9001 Certification

FDA Maharashtra

Licensed by FDA Maharashtra

IEC License DGFT

IEC License issued by DGFT